Results 41 to 50 of about 835,152 (295)

Structure‐forward targeting of claudins with synthetic binders

FEBS Letters, EarlyView.
Claudins form the paracellular barriers between epithelial and endothelial tissues at tight junctions and are targets for molecular binders with the goal of modulating barrier permeability. Claudin‐binding molecules are relevant in drug delivery or in altering claudin interactions with disease‐causing proteins.
Alex J. Vecchio
wiley   +1 more source

Translophagy—A potential link between autophagy impairment and translational errors

FEBS Letters, EarlyView.
Neurodegenerative diseases are characterised by the accumulation of abnormal proteins and protein aggregates, but their origin often remains unknown. We propose that selective autophagy removes damaged protein‐making machinery, preventing errors during protein synthesis.
Mykola V. Korolchuk, Gailing Ma, Robin Antrobus, Diego Manni, Marco Trevisan‐Herraz, Mustafa Khwaja, Max Brown, Gavin D. Richardson, Masaaki Komatsu, Daniel Erskine, Viktor I. Korolchuk, Tetsushi Kataura   +11 more
wiley   +1 more source

Thiol-ene click-functionalized polybutadiene elastomers achieve durable and biocompatible polyurethanes for long-term implantable systems

Materials & Design
Conventional polyurethanes for implants suffer from hydrolytic/oxidative degradation due to ester/ether bonds. To overcome this, in this research, we have developed aging-resistant implantable medical polyurethanes to address the issue of their limited ...
Minghui Cui, Yu Liu, Guohui Tian, Junyi Zhou, Fenglong Li, Xiaolin Wang, Jing Chen, Haiming Chen, Jin Zhu, Jing Chen   +9 more
doaj   +1 more source

Comparison between tensile behavior of epoxy and polyester matrix composites reinforced with eucalyptus fibers

Journal of Materials Research and Technology, 2017
Investigations and uses of composites reinforced with natural fibers have been growing over the last decades. These composites offer economical, technical, societal and environmental advantages.
Caroline G. de Oliveira, Frederico M. Margem, Sergio N. Monteiro, Felipe Perissé Duarte Lopes   +3 more
doaj   +1 more source

Leucine‐rich glioma inactivated 1 (LGI1) is a ganglioside‐binding protein

FEBS Letters, EarlyView.
Neuronal hyperexcitability associated with a decrease/absence of the extracellular protein LGI1 has been suggested to be primarily due to the downregulation of Kv1 channel expression. The molecular mechanisms underlying this decrease have not yet been elucidated.
Kévin Debreux, Christian Lévêque, Fodil Azzaz, Marion Sangiardi, Sarosh R Irani, Michael Seagar, Jacques Fantini, Oussama El Far   +7 more
wiley   +1 more source

ABRASIVE WEAR RESISTANCE OF POLYMERS REINFORCED BY SILICON CARBIDE NANOFIBERS [PDF]

Journal of the Egyptian Society of Tribology, 2019
Scratch test was carried out to investigate the abrasion wear resistance gained by the polymeric composites. They were polymethyl methacrylate (PMMA), low density polyethylene (LDPE), high density polyethylene (HDPE), polypropylene (PP) and epoxy epoxy ...
M. E. Marzouk, W. Y. Ali
doaj   +1 more source

The ubiquitin system in normal and infected germinal center B cells

FEBS Letters, EarlyView.
The ubiquitin system plays a central role in germinal center (GC) B cells, influencing differentiation to long‐lived memory B cells. Oncogenic gammaherpesviruses gain access to memory B cells by establishing latency in GC B cells. Mapping ubiquitin mechanisms in normal and infected GC B cells will define specific molecular circuits in B cells germane ...
Destiny Davis, Lesly Mejia, Emily K Moser   +2 more
wiley   +1 more source

Preparation of Polymeric Composites from Polypropylene and Palm Fronds and the Study of Some of Their Physical Properties

مجلة بغداد للعلوم, 2020
:               In this study a type of polymeric composites from melting poly propylene as a basic substance with Palm fronds powder were prepared.
Ebtehag Sulyman, Noaman Sulyman
doaj   +1 more source

Unlocking the potential of cell‐permeable nanobodies for intracellular applications

FEBS Letters, EarlyView.
This review outlines current strategies for delivery of nanobodies into cells and highlights recent examples of functional applications. By addressing and manipulating intracellular targets, these molecules hold great potential for treating cancer, respiratory diseases and neurological disorders, making this a vibrant area of research in the biomedical
Mariona Gené‐Verdés, Luise Franz, Christian P.R. Hackenberger   +2 more
wiley   +1 more source

Effects of Bromelain and Papain in Tooth Whitening and Caries Removal: A Literature Review

Dentistry Journal
Background/Objectives: The objective of this review is to establish a solid base of information regarding the use of proteolytic enzymes to replace hydrogen peroxide/carbamide in teeth whitening products. The use of proteolytic enzymes, such as bromelain
Stanca Cuc, Amalia Moldovan, Marioara Moldovan, Codruta Sarosi, Smaranda Buduru, Cecilia Bacali, Doina Prodan, Viorica Lazar, Sorin Claudiu Man   +8 more
doaj   +1 more source