Results 131 to 140 of about 90,812 (270)

RNA‐Micelles as Self‐Assembling Structures for Efficient Co‐Delivery of Synergistic siRNA and Nucleoside Analogues to Treat CRC Lung Metastasis

Advanced Functional Materials, EarlyView.
Two kinds of self‐assembled RNA micelles were used to co‐deliver synergistic siRNA and nucleoside analogues for the treatment of colorectal cancer lung metastases. Near‐complete elimination of lung cancer metastases was confirmed in an orthotopic lung metastasis model constructed using human colorectal cancer lung metastases patient surgical samples to
Kai Jin, Piotr Rychahou, Daniel W. Binzel, B. Mark Evers, Peixuan Guo   +4 more
wiley   +1 more source

Photogeneration of Hydrogen in Water via Self‐Assembly‐Induced Colloidal Covalent Organic Framework Particles

Small Science
The synthesis of colloidal imine‐linked Covalent Organic Framework nanoparticles using a polymeric growth‐blocking agent that facilitates both in situ colloidal stabilization and size control. This new surfactant‐free method, called Self‐Assembly‐Induced
Axelle Larrieu, Sabuj Kanti Das, Aurelien Viterisi, Laurent Billon   +3 more
doaj   +1 more source

Bio‐Orthogonally Crosslinked Supramolecular Polymer Bottlebrush Hydrogels for Long‐Term 3D Cell Culture

Advanced Functional Materials, EarlyView.
Fibrous benzenetrispeptide (BTP) hydrogels, fabricated via strain‐promoted azide‐alkyne cycloaddition (SPAAC) crosslinking, form robust, bioinert networks. These hydrogels can support 3D cell culture, where cell viability and colony growth depend on the fiber content.
Ceren C. Pihlamagi, David Pretzel, Peer Nölte, Kourosh Rezaei, Ulrich S. Schubert, Johannes C. Brendel   +5 more
wiley   +1 more source

Controlled Synthesis and Crystallization-Driven Self-Assembly of Poly(ε-caprolactone)-b-polysarcosine Block Copolymers

Molecules
Poly(ε-caprolactone)-b-polysarcosine (PCL-b-PSar) block copolymers (BCPs) emerge as a promising alternative to conventional poly(ε-caprolactone)-b-poly(ethylene oxide) BCPs for biomedical applications, leveraging superior biocompatibility and ...
Zi-Xian Li, Chen Yang, Lei Guo, Jun Ling, Jun-Ting Xu   +4 more
doaj   +1 more source

Liquid Crystalline Inverted Lipid Phases and Reverse Micelles in Drug Delivery: From Molecular Design to Therapeutic Potential

Advanced Functional Materials, EarlyView.
Liquid crystalline inverted lipid phases and reverse micelles are self‐assembled lipid nanostructures that enhance the solubility, stability, and delivery of diverse therapeutics. This review integrates their physicochemical principles, formulation strategies, drug loading mechanisms, and biomedical applications, highlighting their growing ...
Numan Eczacioglu, Mulazim Hussain Asim, Soheil Haddadzadegan, Andreas Bernkop‐Schnürch   +3 more
wiley   +1 more source

Gaining Structural Control by Modification of Polymerization Rate in Ring-Opening Polymerization-Induced Crystallization-Driven Self-Assembly

ACS Polymers Au, 2022
Paul Joshua Hurst, Annissa A. Graham, Joseph P. Patterson   +2 more
doaj   +1 more source

Block Copolymers: Emerging Building Blocks for Additive Manufacturing

Advanced Functional Materials, EarlyView.
This review addresses how block copolymer (BCP) physics and rheology have led to the widespread use of BCPs in advanced additive manufacturing techniques, with particular emphasis on the untapped potential of these nanostructured materials toward achieving multi‐scale architected materials with unique, programmable material properties.
Alice S. Fergerson, Hemish B. Thakkar, Jiaen Wu, Emily C. Davidson   +3 more
wiley   +1 more source

Enhanced precise therapy of ROS-sensitive dual-layer shell nanoparticles loading quercetin on DSS-induced ulcerative colitis mice

APL Materials
Ulcerative colitis (UC) is an intestinal condition, involving inflammatory response, apoptosis, and associated processes. As one of the traditional Chinese medicine treatments for UC, quercetin has received attention because it can attenuate inflammation.
Yang Bai, Danling Jiang, Boda Wu, Jiao Peng, Ji Wang, Yuhui Chen, Xi Li   +6 more
doaj   +1 more source

Self‐Refreshing Bi‐Based Active Sites for Efficient and Durable Electrochemical CO2 Reduction

Advanced Functional Materials, EarlyView.
A self‐refreshing Bi‐based catalyst is developed through the fabrication of a novel basic bismuth nitrate pre‐catalyst, which exhibits differential active sites of Bi2O2CO3 at low potentials and metallic Bi phases at high potentials, self‐repairing capability, and thus wide‐potential‐window efficiency and ultralong durability toward electrochemical CO2
Yuxuan Xiao, Xiaoling Lai, Jinxian Feng, Ziwen Feng, Wendi Zhang, Lun Li, Weng Fai IP, Hui Pan   +7 more
wiley   +1 more source

Proteins, Processing, and Properties of Adhesive Fluid Condensates Purified from Mussels

Advanced Functional Materials, EarlyView.
Mussels exhibit an unmatched proficiency for adhering to wet surfaces in salty environments—a remarkable ability that could inspire new biomedical and technical glues. The fluid protein condensates used to form the underwater mussel glue are extracted, reconstituted and characterized with advanced spectroscopy and nanomechanical analysis, revealing ...
Mathieu D. Rivard, Max Renner‐Rao, Nahid Hassanpour, Franziska Jehle, Chang‐Sheng Wang, Duy Anh Pham, Daniel J. Jackson, Xavier Banquy, Matthew J. Harrington   +8 more
wiley   +1 more source