Results 241 to 250 of about 90,812 (270)

High‐Throughput Generation of Tumor Spheroids via Droplet Microfluidics for siRNA‐Loaded Nanomedicine Assessment

Advanced Healthcare Materials, EarlyView.
A droplet microfluidic platform is employed to enable high‐throughput, uniform tumor spheroid generation for evaluating siRNA‐loaded nanomedicines at the protein level. As a proof of concept, breast (MCF‐7) and brain (U87 MG) cancer cell lines are investigated using this platform, revealing penetration profiles and therapeutic responses between the two
Ling Liu, Guoying Wang, Yang Zhang, Bingyang Shi, Ming Li   +4 more
wiley   +1 more source

Smart Catheters for Diagnosis, Monitoring, and Therapy

Advanced Healthcare Materials, EarlyView.
This study presents a comprehensive review of smart catheters, an emerging class of medical devices that integrate embedded sensors, robotics, and communication systems, offering increased functionality and complexity to enable real‐time health monitoring, diagnostics, and treatment. Abstract This review explores smart catheters as an emerging class of
Azra Yaprak Tarman, Samiha Ahmed, Majed Othman Althumayri, Megan Guy, Darlenne Chavez Lugo, Frances S. Ligler, George T. Ligler, Rahmi Oklu, Hiroshi Kawahira, Michael J. McShane, Jun Kameoka, Jonathan Bova, Hatice Ceylan Koydemir   +12 more
wiley   +1 more source

Redefining Therapies for Drug‐Resistant Tuberculosis: Synergistic Effects of Antimicrobial Peptides, Nanotechnology, and Computational Design

Advanced Healthcare Materials, EarlyView.
Antimicrobial peptide (AMP)‐loaded nanocarriers provide a multifunctional strategy to combat drug‐resistant Mycobacterium tuberculosis. By enhancing intracellular delivery, bypassing efflux pumps, and disrupting bacterial membranes, this platform restores phagolysosome fusion and macrophage function.
Christian S. Carnero Canales, Jessica Ingrid Marquez Cazorla, Renzo Marianito Marquez Cazorla, Aline Martins dos Santos, Jonatas Lobato Duarte, Letícia Oliveira Catarin Nunes, Túlio Custódio Reis, Lara Cerazi Salvador, Norival Alves Santos‐Filho, Rafael Miguel Sábio, Hélder A. Santos, Fernando Rogério Pavan   +11 more
wiley   +1 more source

Hybrid Nanofibers for Multimodal Accelerated Wound Healing

Advanced Healthcare Materials, EarlyView.
Fabrication of wound healing scaffolds based on biocompatible nanofibers. Nanofibers offering high surface area, flexibility, and biocompatibility significantly improved the healing outcome in vivo. Histological, immunological, and anti‐inflammatory markers are noticeably better in treated wounds.
Viraj P. Nirwan, Bence Bajusz, Norbert Fabók, Marina Rudan Dimlic, Jelena Budimir, Tshepang Mqatywa, Miklós Gyöngy, Márton Ferencz, Dorottya Kocsis, Olexandr Bondarenko, Mariia Rolduhina, Milena Lengyel, Istvan Antal, Rebecca Hengsbach, Franciska Erdő, Amir Fahmi   +15 more
wiley   +1 more source

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Ethylene‐Coordinative Chain‐Transfer Polymerization‐Induced Self‐Assembly (CCTPISA)

Chemistry – A European Journal, 2022
AbstractBlock copolymers based on ethylene (E) and butadiene (B) were prepared using the ansa‐bis(fluorenyl) complex {Me2Si(C13H8)2Nd(BH4)2Li(THF)}2 in combination with (n‐Bu)(n‐Oct)Mg (BOMAG) as a chain‐transfer agent. The diblock copolymers incorporating a soft poly(ethylene‐co‐butadiene) segment, called ethylene butadiene rubber (EBR), and a hard ...
Nicolas Baulu, Marvin Langlais, Pierre‐Yves Dugas, Julien Thuilliez, François Jean‐Baptiste‐dit‐Dominique, Muriel Lansalot, Christophe Boisson, Franck D'Agosto   +7 more
openaire   +2 more sources

Sequence-Controlled Polymerization-Induced Self-Assembly

ACS Macro Letters, 2019
We herein present sequence-controlled polymerization-induced self-assembly (PISA) via photoswitchable reversible addition-fragmentation chain transfer (RAFT) copolymerization of oppositely-charged monomers using polyethylene glycol chain transfer agent in water at 25 °C.
Lei Wang, Yi Ding, Qizhou Liu, Qingqing Zhao, Xinchao Dai, Xinhua Lu, Yuanli Cai   +6 more
openaire   +2 more sources

Biosurfaces Fabricated by Polymerization-Induced Surface Self-Assembly

Langmuir, 2020
Surface biofunctionalization provides an approach to the fabrication of surfaces with improved biological and clinical performances. Biosurfaces have found increasing applications in many areas such as sensing, cell growth, and disease detection. Efficient synthesis of biosurfaces without damages to the structures and functionalities of biomolecules is
Wen Zhong, Wangmeng Hou, Yingze Liu, Li Liu, Hanying Zhao   +4 more
openaire   +2 more sources

ROMPISA: Ring-Opening Metathesis Polymerization-Induced Self-Assembly

ACS Macro Letters, 2017
Herein we report a polymerization-induced self-assembly (PISA) process with ring-opening metathesis polymerization (ROMP). We utilize a peptide-based norbornenyl monomer as a hydrophobic unit to provide a range of nanostructures at room temperature yet at high solids concentrations of 20 wt % in combination with an oligoethylene glycol based ...
Daniel B. Wright, Mollie A. Touve, Lisa Adamiak, Nathan C. Gianneschi   +3 more
openaire   +2 more sources

Ultrafast Xanthate‐Mediated Photoiniferter Polymerization‐Induced Self‐Assembly (PISA)

Angewandte Chemie International Edition, 2023
AbstractPolymerization‐induced self‐assembly (PISA) is a powerful technique for preparing block copolymer nanostructures. Recently, efforts have been focused on applying photochemistry to promote PISA due to the mild reaction conditions, low cost, and spatiotemporal control that light confers.
Jared I. Bowman, Cabell B. Eades, Maria A. Vratsanos, Nathan C. Gianneschi, Brent S. Sumerlin   +4 more
openaire   +2 more sources

Polymerization-induced self-assembly of random bottlebrush copolymers

Polymer Chemistry, 2022
RAFT-mediated polymerization-induced self-assembly (PISA) was exploited to evaluating the self-assembly behavior of amphiphilic random P[PEGMA-co-(HEMA-g-PS)] bottlebrush copolymers.
Gaohuai Mei, Yinan Zheng, Yeran Fu, Meng Huo   +3 more
openaire   +1 more source