Results 71 to 80 of about 153,986 (278)

Growing Polymer Vesicles Generated by Polymerization Induced Self-Assembly Coupled With a Living Chemical Reactor

Frontiers in Bioengineering and Biotechnology, 2020
Chemical oscillatory reactions have attracted intensive attention due to their autonomous, continuous, and periodic features. Herein, the radicals generated in Belousov-Zhabotinsky (BZ) oscillator was used to initiate RAFT (reversible addition ...
Zhihui Lu, Jinshan Guo
doaj   +1 more source

Translating whole‐genome doubling into precision medicine in cancer

Molecular Oncology, EarlyView.
Whole‐genome doubling creates a WGD‐positive tumor state characterized by persistent chromosomal instability, karyotypic diversification, and cellular stress. These same biological pressures drive aggressive tumor evolution while exposing therapeutic vulnerabilities, providing a rationale for WGD‐informed precision medicine. Whole‐genome doubling (WGD)
Sejung Lee, Junghyeok Lim, Jinhyuk Bhin
wiley   +1 more source

Tyrosinase Driven‐Intracellular Polymerization of a Porphyrin Derivative Induced Immunogenic Death of Melanoma Cells and Strengthened Photodynamic Therapy

Advanced Science
Therapeutic agents usually must reach diseased tissue and then exert biological effects. While numerous targeted and stimuli‐responsive delivery systems have been developed, their therapeutic outcomes have been limited due to the lack of “precision”.
Mian Tang, Junteng Qiu, Yunfeng Lu, Yahui Song, Xinyu Zhou, Tianshun Duan, Xuanqi Peng, Caixia Yin, Cheng Gao, Ruibing Wang   +9 more
doaj   +1 more source

Targeting transcription factors associated with hemoglobinopathies: Lessons from successful interventions and implications for cancer

Molecular Oncology, EarlyView.
This review summarizes the transcription factors, repressive chromatin‐modifying complexes, and epigenetic mechanisms that control fetal hemoglobin repression. Notably, many regulators of γ‐globin silencing also function in transcriptional and epigenetic networks that drive cancer, highlighting opportunities to translate advances in hemoglobinopathy ...
Meigen Yu, Puspa Das, Xing Zhang, Xiaodong Cheng   +3 more
wiley   +1 more source

Large‐scale bidirectional arrayed genetic screens identify OXR1 and EMC4 as modifiers of αSynuclein aggregation

FEBS Open Bio, EarlyView.
Activation of the mitochondrial protein OXR1 increases pSyn129 αSynuclein aggregation by lowering ATP levels and altering mitochondrial membrane potential, particularly in response to MSA‐derived fibrils. In contrast, ablation of the ER protein EMC4 enhances autophagic flux and lysosomal clearance, broadly reducing α‐synuclein aggregates.
Sandesh Neupane, Lea Nikolić, Lorenzo Maraio, Thomas Goiran, Nathan Karpilovsky, Stefano Sellitto, Vangelis Bouris, Jiang‐An Yin, Ronald Melki, Edward A Fon, Adriano Aguzzi, Elena De Cecco   +11 more
wiley   +1 more source

Modelling Polymerization-Induced Self Assembly (PISA)

, 2019
12 pages, 10 ...
Shupanov, Ruslan, Kos, Pavel, Gavrilov, Alexei, Chertovich, Alexander   +3 more
openaire   +2 more sources

Polymer-inorganic hybrid nanoparticles via polymerization-induced self-assembly [PDF]

, 2019
Silica nanoparticles are commonly integrated within polymeric matrices to form composite materials, due to their non-toxic nature, chemical resistance and physical properties.
Teo, GH (15933944)
core   +1 more source

Light‐Assisted 3D Printing Techniques and Photocrosslinking Strategies: Recent Advances in Musculoskeletal Tissue Engineering

Advanced Engineering Materials, EarlyView.
In this review, the current state of light‐assisted 3D printing as it pertains to engineering musculoskeletal tissues including bone, cartilage, skeletal muscle, tendon, and ligaments is summarized. Common printing techniques, photoreactive materials, and study design choices are compiled and reviewed.
Meagan Morgan, Bin Zhang, Roger Narayan
wiley   +1 more source

A Novel Fabrication of Single Electron Transistor from Patterned Gold Nanoparticle Array Template-Prepared by Polystyrene Nanospheres

Nanomaterials, 2022
In this paper, polystyrene microspheres were firstly prepared by seeded emulsion polymerization, and the uniform monolayer of polystyrene microspheres was prepared on the substrate by the dipping method.
Jingyue Fang, Xinxing Li, Wenke Xie, Kehui Sun   +3 more
doaj   +1 more source

Methacrylate-based amphiphilic block copolymers in solution and at surfaces : synthesis, characterization and self-assembly [PDF]

, 2008
Part 1. Introduction General concept of polymer self-assembly, synthesis of amphiphilic block copolymers and their application in biotechnology are briefly presented.
Rakhmatullina, Ekaterina
core   +1 more source