Results 161 to 170 of about 659,954 (193)
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Genetic Polymorphisms in Sepsis
Critical Care Nursing Clinics of North America, 2009The number of genetic polymorphisms shown to play a role in sepsis continues to increase. At the same time, platforms for genetic sequencing and expression analysis are being refined, allowing unprecedented data generation. International databases may soon facilitate synchrony of genotypic and phenotypic data using enormous numbers of septic patients ...
Allen Namath, Andrew J. Patterson
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GENETIC POLYMORPHISMS AND SEPSIS
Shock, 2005Sepsis is a polygenic and complex syndrome that is initiated by infection and is characterized by a systemic inflammatory response. Genetic polymorphisms in the immune response to infection have been shown to be associated with clinical outcomes. Functional and association studies involving genetic polymorphisms in essential genes, including Toll-like ...
Michael B. Fessler +2 more
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Endometriosis and Genetic Polymorphisms
Obstetrical & Gynecological Survey, 2007Endometriosis is a benign gynecological disease with an unclear pathophysiology characterized by ectopic endometrium causing endometrium-like inflammatory lesions outside the uterine cavity. Recently, a number of studies have investigated genetic polymorphisms as a possible factor contributing to the development of endometriosis.
Thomas D'Hooghe +2 more
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Proceedings of the Royal Society of London. Series B. Biological Sciences, 1966
The title of this Symposium ‘From Mendel’s factors to the genetic code’ emphasizes a single aspect of genetic research. That is unfortunate in a subject of such wide scope. Even in the most general terms, it naturally involves far more than analysing the fine structure of the genetic material and the physiological paths by which the genes ...
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The title of this Symposium ‘From Mendel’s factors to the genetic code’ emphasizes a single aspect of genetic research. That is unfortunate in a subject of such wide scope. Even in the most general terms, it naturally involves far more than analysing the fine structure of the genetic material and the physiological paths by which the genes ...
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Allergy and ACP1 genetic polymorphism
Allergy and Asthma Proceedings, 2007The ACP1 (acid phosphatase locus 1) gene encodes a highly polymorphic low molecular weight protein tyrosine phosphatase (LMPTP) involved in the modulation of various signal transduction pathways including T-cell receptor. Previous studies suggest an association of this enzyme with allergic disorders.
BOTTINI, EGIDIO +7 more
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Phosphoglucomutase genetic polymorphism of newborns
American Journal of Human Biology, 2001An association of the phosphoglucomutase locus 1 (PGM1) genetic polymorphism with repeated spontaneous abortion (RSA), with intrauterine development in both normal and diabetic pregnancies, and with fertility has been reported in previous studies.
Gloria Bottini, F +7 more
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The Genetics of the Human APOE Polymorphism
Rejuvenation Research, 2011Abstract The genetic origin of the three common variants of the human apolipoprotein E (apoE) protein, known as E2, E3 and E4, was understood in 1981, and since the mid 1980s these are probably the most-studied protein variants in human races. They have been related to a number of age-related diseases, including Alzheimer disease, as well as to ...
Grazia D'Onofrio +5 more
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Aspirin Resistance and Genetic Polymorphisms
Journal of Thrombosis and Thrombolysis, 2002Differences in genetic makeup or polymorphisms can affect individual drug response. Detecting genetic variation may help predict how a patient will respond to a drug and could be used as a tool to select optimal therapy, tailor dosage regimens, and improve clinical outcomes. The data are replete relative to the therapeutic efficacy of aspirin (ASA) for
Pritesh J. Gandhi +1 more
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Genetic Polymorphism of Plasminogen
Pathophysiology of Haemostasis and Thrombosis, 1988By isoelectric focusing in a pH range of pH 3.5 – 9.5 or of pH 5–8, and by using a functional or an immunological detection, a genetic polymorphism of plasminogen can be demonstrated. In Caucasoids, 2 common alleles – PLG*A (frequency 0.67) and PLG*B (frequency 0.30) – as well as several rare variants (sum of their frequencies 0.03) exist.
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