Results 161 to 170 of about 3,200,406 (285)

Association of angiotensin I converting enzyme gene I/D polymorphism and coronary artery disease in the Pakistani population. [PDF]

Sci Prog
Saba N, Rehman S, Munir S, Noor A.
europepmc   +1 more source

Genetic variation in IL28B predicts hepatitis C treatment-induced viral clearance

Nature, 2009
D. Ge, J. Fellay, A. Thompson, J. Simon, K. Shianna, T. Urban, E. Heinzen, P. Qiu, A. Bertelsen, A. Muir, M. Sulkowski, J. Mchutchison, D. Goldstein   +12 more
semanticscholar   +1 more source

Assessment and Mitigation of CRISPR‐Cas9‐Induced Nontargeted Translocations

Advanced Science, EarlyView.
Various inverted repeat elements are dispersed throughout genomes. This study reveals that these elements can cause significant chromosomal rearrangements when CRISPR editing occurs in their proximity. The risk can be mitigated by incorporating inverted repeat‐homologous segments into the CRISPR system, which represents a promising strategy for ...
Zhiyang Hou, Qiyi Yi, Mengying Wu, Lijun Wu, Fanghua Li, Ting Wang, Po Bian   +6 more
wiley   +1 more source

Effects of Methylenetetrahydrofolate Reductase Polymorphism on Clinical Features of High-Risk Psychosis Before Schizophrenia. [PDF]

Psychiatry Investig
Wan L, Han X.
europepmc   +1 more source

MeCP2 Lactylation Protects against Ischemic Brain Injury by Transcriptionally Regulating Neuronal Apoptosis

Advanced Science, EarlyView.
MeCP2 lactylation protects against ischemic stroke by reducing brain infarct volume and improving neurological outcomes. Lactylation at K210/K249 exerts neuroprotective effects by repressing the transcription of apoptosis‐associated genes, including Pdcd4 and Pla2g6. HDAC3 and p300 serve as key regulatory enzymes for MeCP2 lactylation following stroke.
Min Sun, Yuxin Zhang, Rui Mao, Yan Chen, Pinyi Liu, Lei Ye, Siyi Xu, Junqiu Jia, Shu Shu, Huiya Li, Yanping Yin, Shengnan Xia, Yanting Chen, Yun Xu   +13 more
wiley   +1 more source

The development of ideal insertion and deletion (InDel) markers and initial indel map variation in cucumber using re-sequenced data. [PDF]

BMC Genomics
Yang J, Meng P, Mi H, Wang X, Yang J, Fu S, Gong W, Bao R, Deng W, Wu H, Liu Z, Yang S, Ni J, Liu J, Shi H.   +14 more
europepmc   +1 more source

RAB3B Dictates mTORC1/S6 Signaling in Chordoma and Predicts Response to mTORC1‐Targeted Therapy

Advanced Science, EarlyView.
RAB3B is unveiled as a prominent oncogenic regulator in chordoma, which can block the DUSP12‐mediated dephosphorylation of p‐S6 (S235/236). The combination of RAB3B and p‐S6 indicates a good prognostic value and predicts mTORC1 inhibitors response for chordoma patients.
Jianxuan Gao, Jiali Jin, Runzhi Huang, Siqiao Wang, Sihui Song, Yu Zhang, Yongai Li, Jun Lin, Zhengyan Chang, Zongqiang Huang, Wei Sun, Huabin Yin, Dianwen Song, Jianru Xiao, Ping Wang, Tong Meng   +15 more
wiley   +1 more source

Psychosocial and genetic determinants of tobacco smoking as an addictive disease [PDF]

Vojnosanitetski Pregled, 2006
Pešut Dragica, Bursuc Bogdana, Ciobanu Laura, Nagorni-Obradović Ljudmila   +3 more
doaj   +1 more source

The frequency of the ACTN3 polymorphism in Brazil: a systematic review and meta-analysis. [PDF]

BMC Med Genomics
Silvino VO, Ferreira CP, Apaza HM, de Souza-Junior VS, Ribeiro SLG, Almeida SS, Dos Santos MAP.   +6 more
europepmc   +1 more source

A Solution‐Based Deposition Method Enabling Pigment Blue Edible Electrochemical Transistors

Advanced Science, EarlyView.
A novel solution‐based method is presented to produce Copper Phthalocyanine fibrous films displaying effective ion permeability and enhanced transconductance in electrolyte‐gated transistors architectures. Using these films, the first instance of a fully edible electrolyte‐gated transistor with volumetric capacitance, targeting in‐body applications, is
Alessandro Luzio, Fabrizio M. Ferrarese, Matteo Butti, Alberto D. Scaccabarozzi, Bojan Petrović, Sanja Kojić, Goran Stojanović, Simone Fiorini Granieri, Shubham Tanwar, Adrica Kyndiah, Mario Caironi   +10 more
wiley   +1 more source