Results 181 to 190 of about 3,539,255 (350)

Genetic predisposition to neuroblastoma mediated by a LMO1 super-enhancer polymorphism

open access: yesNature, 2015
D. Oldridge   +27 more
semanticscholar   +1 more source

Nanocrystalline Cellulose from the Solitary Tunicate Phallusia Mammillata, a Valuable Nanocellulose Precursor

open access: yesAdvanced Sustainable Systems, EarlyView.
This study explores the potential of locally harvested Phallusia mammillata, a tunicate usually discarded as waste from mussles farming as a viable source for producing various high‐grade cellulose derivatives in the form of nanofibrils (NFC) and nanocrystals (CNC). Abstract Ascidians are ubiquitous filter‐feeding marine invertebrates, the only animals
Andrea Riccioni   +6 more
wiley   +1 more source

Reinforcing the Strategy: Enhanced Efficiency of Electrospun PVDF Hybrid Nanocomposites‐Based Triboelectric Nanogenerators with p‐NiO/n‐ZnO Interfaces for Energy Harvesting

open access: yesAdvanced Sustainable Systems, EarlyView.
This study presents high‐performance PVDF‐based triboelectric nanogenerators (TENGs) enhanced with NiO–ZnO bimetallic nanoparticles. The optimized PN7/Z‐0.5 composite achieves remarkable energy harvesting efficiency, significantly outperforming pristine PVDF.
Hema Malini Venkatesan   +6 more
wiley   +1 more source

Digital droplet PCR versus quantitative PCR for lipoprotein (a) kringle IV type 2 repeat polymorphism genetic characterization. [PDF]

open access: yesJ Clin Lab Anal
Barbieri G   +11 more
europepmc   +1 more source

Presbycusis: Pathology, Signal Pathways, and Therapeutic Strategy

open access: yesAdvanced Science, EarlyView.
In ARHL, the stria vascularis, acting as a cochlear battery, gradually loses its ability to maintain the endocochlear potential, leading to impaired hair cell function and progressive hearing loss. Single‐cell sequencing reveals age‐related cellular changes in the cochlea, providing insights into the underlying mechanisms of aging and potential ...
Xiaoxu Zhao   +12 more
wiley   +1 more source

Genetic Variant BDNF (Val66Met) Polymorphism Alters Anxiety-Related Behavior

open access: yesScience, 2006
Zhe-yu Chen   +11 more
semanticscholar   +1 more source

Development and Validation of Machine Learning‐Based Marker for Early Detection and Prognosis Stratification of Nonalcoholic Fatty Liver Disease

open access: yesAdvanced Science, EarlyView.
This study constructs a stacked multimodal machine learning model for nonalcoholic fattly liver disease (NAFLD) by integrating genetic and clinical features, and synthesize an in‐silico quantitative marker (ISNLD) that enables personalized risk stratification for intrahepatic and extrahepatic outcomes of high‐risk individuals of NAFLD.
Lushan Xiao   +14 more
wiley   +1 more source

Acod1 Promotes PAD4 Ubiquitination via UBR5 Alkylation to Modulate NETosis and Exert Protective Effects in Sepsis

open access: yesAdvanced Science, EarlyView.
In this study, Acod1 knockout in CLP mice significantly increases peripheral blood NET levels, exacerbating inflammation, organ damage, and reducing survival. Further research shows that UBR5 interacts with PAD4, a key NET formation protein. Acod1/itaconate (ITA) enhances the enzymatic activity of UBR5 by alkylating the Cys2768 site, promoting the K48 ...
Huifan Liu   +10 more
wiley   +1 more source

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