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Single-Strand Conformational Polymorphism Analysis: Basic Principles and Routine Practice
2005Single-strand conformational polymorphism (SSCP) analysis is a simple and sensitive technique for mutation detection and genotyping. The principle of SSCP analysis is based on the fact that single-stranded DNA has a defined conformation. Altered conformation due to a single base change in the sequence can cause single-stranded DNA to migrate ...
Yanbin, Dong, Haidong, Zhu
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High-throughput single-strand conformation polymorphism analysis by capillary electrophoresis
Journal of Chromatography B: Biomedical Sciences and Applications, 2000Mutation detection plays a great role in genetic and medical research and clinical diagnosis of inherited diseases and particular cancers. Single-strand conformation polymorphism (SSCP) analysis is one of the most popular methods for detection of mutations.
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Single-Strand Conformation Polymorphism Analysis
Cold Spring Harbor Protocols, 2006Anne E, Jedlicka, Steven R, Kleeberger
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Single-Strand Conformation Polymorphism Mutation Analysis of the p53 Gene
2003Single-strand conformation polymorphism (SSCP) is a rapid and convenient procedure by which differences in the base composition of short DNA strands may be detected (1, 2). A useful application of this is in the comparison of polymerase chain reaction (PCR) generated products from gene coding sequences of unknown or patient material with a known wild ...
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Conformational Dynamics of Poly(T) Single-Stranded DNA at the Single-Molecule Level
Journal of Physical Chemistry Letters, 2021Tae-Hee Lee
exaly
SSCP (single strand conformation polymorphism)
EMC - Biologie médicale, 2008openaire +1 more source
Single-Strand Conformation Polymorphism (SSCP) Analysis
1998William C. Jordan +2 more
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