Results 111 to 120 of about 828,217 (183)

MeCP2 Lactylation Protects against Ischemic Brain Injury by Transcriptionally Regulating Neuronal Apoptosis

Advanced Science, EarlyView.
MeCP2 lactylation protects against ischemic stroke by reducing brain infarct volume and improving neurological outcomes. Lactylation at K210/K249 exerts neuroprotective effects by repressing the transcription of apoptosis‐associated genes, including Pdcd4 and Pla2g6. HDAC3 and p300 serve as key regulatory enzymes for MeCP2 lactylation following stroke.
Min Sun, Yuxin Zhang, Rui Mao, Yan Chen, Pinyi Liu, Lei Ye, Siyi Xu, Junqiu Jia, Shu Shu, Huiya Li, Yanping Yin, Shengnan Xia, Yanting Chen, Yun Xu   +13 more
wiley   +1 more source

The evolutionary cost of homophily: Social stratification facilitates stable variant coexistence and increased rates of evolution in host-associated pathogens. [PDF]

PLoS Comput Biol
Li S, Gulisija D, Carja O.
europepmc   +1 more source

RAB3B Dictates mTORC1/S6 Signaling in Chordoma and Predicts Response to mTORC1‐Targeted Therapy

Advanced Science, EarlyView.
RAB3B is unveiled as a prominent oncogenic regulator in chordoma, which can block the DUSP12‐mediated dephosphorylation of p‐S6 (S235/236). The combination of RAB3B and p‐S6 indicates a good prognostic value and predicts mTORC1 inhibitors response for chordoma patients.
Jianxuan Gao, Jiali Jin, Runzhi Huang, Siqiao Wang, Sihui Song, Yu Zhang, Yongai Li, Jun Lin, Zhengyan Chang, Zongqiang Huang, Wei Sun, Huabin Yin, Dianwen Song, Jianru Xiao, Ping Wang, Tong Meng   +15 more
wiley   +1 more source

Genome-wide DNA polymorphisms in two peatland adapted Coffea liberica varieties. [PDF]

BMC Genom Data
Melia T, Fatayat, Wahibah NN, Fatonah S, Roslim DI, Adnan A.   +5 more
europepmc   +1 more source

Silicon Carbide Photonic Crystal Photoelectrode

Advanced Science, EarlyView.
A 3C‐SiC photoelectrode with a slanted parabolic pore photonic crystal architecture enhances photogeneration for efficient photoelectrochemical water splitting through the remarkable light‐trapping capabilities of photonic crystal slow‐light modes.
Xiwen Zhang, Sajeev John
wiley   +1 more source

Unexpected absence of a multiple-queen supergene haplotype from supercolonial populations of Formica ants. [PDF]

J Evol Biol
Lagunas-Robles G, Alam Z, Brelsford A.
europepmc   +1 more source

A Solution‐Based Deposition Method Enabling Pigment Blue Edible Electrochemical Transistors

Advanced Science, EarlyView.
A novel solution‐based method is presented to produce Copper Phthalocyanine fibrous films displaying effective ion permeability and enhanced transconductance in electrolyte‐gated transistors architectures. Using these films, the first instance of a fully edible electrolyte‐gated transistor with volumetric capacitance, targeting in‐body applications, is
Alessandro Luzio, Fabrizio M. Ferrarese, Matteo Butti, Alberto D. Scaccabarozzi, Bojan Petrović, Sanja Kojić, Goran Stojanović, Simone Fiorini Granieri, Shubham Tanwar, Adrica Kyndiah, Mario Caironi   +10 more
wiley   +1 more source

Causal relationship between educational attainment and the occurrence of venous thromboembolism. [PDF]

BMC Med Genomics
Guo S, Tan S, Qin S, Xu D, Su H, Chen X.
europepmc   +1 more source

Tuning Aggregation in Liquid‐Crystalline Squaraine Chromophores

Advanced Science, EarlyView.
A novel squaraine dye (SQ) forming columnar liquid crystal (LC) phase is synthesized, whose aggregate state can be tuned without disturbing the columnar structures. The liquid crystallization not only offers a rich spectrum and tuning method of optical property but also a novel path for the prescriptive functionalization of LC SQ materials.
Tianyi Tan, Yu Cao, Changlong Chen, Sanliang Ling, Gaolei Hou, Martin J. Paterson, Xin Wang, Ying Chen, Kai Jiang, Gang He, Goran Ungar, Georg H. Mehl, Feng Liu   +12 more
wiley   +1 more source

Comprehensive systematic review and meta-analysis of the TGF-β1 T869C gene polymorphism and autoimmune disease susceptibility. [PDF]

Front Genet
Zhu Y, Qian A, Cheng Y, Li M, Huang C.
europepmc   +1 more source