Results 131 to 140 of about 24,758 (179)

Isolated Non-Progressive Hemidystonia in a Patient Homozygous for H63D Variant of Hereditary Hemochromatosis: A Case Report and Systematic Literature Review of Movement Disorders in Hereditary Hemochromatosis. [PDF]

Diagnostics (Basel)
Kalampokini S, Plaitakis A, Spanaki C, Xiromerisiou G.   +3 more
europepmc   +1 more source

Atomistic Insights into the Electrochemical Oxygen Evolution Activity of Hollandite IrO2 Surfaces

Advanced Science, EarlyView.
Lattice distortions at tunnel‐structured hollandite IrO2 surfaces reshape Ir‐O bonding: they weaken the σ‐bond contribution in the Ir‐*OH bond while enhancing the π contribution of the Ir‐*O bond. This orbital reorganization in hollandite surfaces stabilizes *O, facilitates the *OH → O step, and lowers the oxygen‐evolution reaction overpotential ...
Sangseob Lee, Kisung Kang, Taehun Lee, Aloysius Soon   +3 more
wiley   +1 more source

Rethinking DeepVariant: Efficient Neural Architectures for Intelligent Variant Calling. [PDF]

Int J Mol Sci
Gurianova A, Pestruilova A, Beliaeva A, Kasianov A, Mikhailova L, Guguchkin E, Karpulevich E.   +6 more
europepmc   +1 more source

Reference‐Guided Chromosome‐by‐Chromosome de novo Assembly at Scale Using Low‐Coverage High‐Fidelity Long‐Reads with HiFiCCL

Advanced Science, EarlyView.
HiFiCCL, as the first assembly framework specifically designed for low‐coverage high‐fidelity reads, improves the assembly quality of existing assemblers and also enhances downstream applications such as large structural variant (SV) detection (>10 000 bp), synteny analysis, pangenome graph construction, and graph‐based individual‐specific germline SVs
Zhongjun Jiang, Weihua Pan, Runtian Gao, Heng Hu, Wentao Gao, Murong Zhou, Yu‐Hang Yin, Zhipeng Qian, Shuilin Jin, Guohua Wang   +9 more
wiley   +1 more source

The therapeutic potential of targeting LYAR in gastric cancer. [PDF]

Future Sci OA
Qin K, Chen GQ, Ling JW, Li YF, Li Q, Li DM, Li B, Li JD, Wu KJ, He RQ, Qin DY, Dang YW, Chen G, Tang YL.   +13 more
europepmc   +1 more source

Soft‐Drug‐Inspired MnSTF Nano‐Adjuvant for Safe and Synergistic cGAS–STING Activation in Tumor Immunotherapy

Advanced Science, EarlyView.
This study introduces MnSTF, a soft‐drug‐inspired nanoadjuvant that overcomes the systemic toxicity of STING agonists. Through Mn2+ coordination with an ENPP1 inhibitor, it enables safe cGAS‐STING activation, remodels the tumor immune microenvironment, and synergizes with radiotherapy or vaccines to elicit robust antitumor immunity.
Guangfei Sun, Jiancheng Pan, Rui Li, Ruoxi Li, Ziyan Liu, Jinhui Wu, Tingsheng Lin, Yiqiao Hu, Ahu Yuan   +8 more
wiley   +1 more source

Chloroplast genome analysis and phylogenetic position of Polygonatum sinopubescens and comparison with related species. [PDF]

PLoS One
Mo ZM, Wei CM, Yu HY, Yang CD.
europepmc   +1 more source

Mendelian Randomization and Double Machine Learning Modeling Reveal Brain Imaging‐Derived Phenotypes as Functional Contributors to 18 Autoimmune Inflammatory Diseases

Advanced Science, EarlyView.
This schematic integrates the eight statistically significant causal relationships identified between 1,366 brain imaging‐derived phenotypes (IDPs) and 18 autoimmune inflammatory diseases (AIDs). Arrows indicate the direction of causality inferred from bidirectional two‐sample MR analyses.
Jinbin Chen, Xin Wang, Haifeng Ding, Bosheng Zheng, Keni Zeng, Chuying Hu, Jiayi Liu, Xiao Zhu, Haibing Yu   +8 more
wiley   +1 more source

Novel SNP Combination for Predictive Osteoporotic Diagnosis. [PDF]

Int J Mol Sci
Sopova JV, Krasnova OA, Semenova PI, Kryukova JD, Vasileva GV, Zhuk AS, Lesnyak OM, Karelkin VV, Neganova IE.   +8 more
europepmc   +1 more source

TOGR3, a Proteasome β4 Subunit, Orchestrates Sugar Homeostasis to Trade Off Growth and Thermotolerance in Rice

Advanced Science, EarlyView.
This study identifies a novel thermoregulatory mechanism in rice: TOGR3 partners with 26S proteasome subunits, including TT1, to drive thermoresponsive ubiquitin–proteasome activity, maintaining sugar homeostasis in stomatal regulation to balance growth and stress resistance.
Biyao Zhang, Xiaoyan Wu, Ting Xu, Feifei Guo, Xiaolu Shen, Cuiping Meng, Yanan Wang, Xue Han, Hong Zhao, Yongbiao Xue   +9 more
wiley   +1 more source