Results 51 to 60 of about 99,456 (209)
Copy Number Variants and Their Association With Intracerebral Hemorrhage Risk: A Case–Control Study
ABSTRACT Introduction Intracerebral Hemorrhage (ICH) is a leading cause of morbidity and mortality worldwide and lacks effective therapeutic interventions. Despite previous studies, the genetic underpinnings of ICH remain poorly understood. We sought to investigate the role of copy number variants (CNVs) in ICH pathophysiology to identify novel ...
Savvina Prapiadou +12 more
wiley +1 more source
One of the most fundamental mathematical contributions of Garrett Birkhoff is the HSP theorem, which implies that a finite algebra B satisfies all equations that hold in a finite algebra A of the same signature if and only if B is a homomorphic image of ...
Bodirsky, Manuel, Pinsker, Michael
core +1 more source
LIN28B Promotes Cancer Cell Dissemination and Angiogenesis
Children diagnosed with high‐risk neuroblastoma have a 5‐year event‐free survival rate of less than 50% and poor outcomes after recurrence. Deregulation of the LIN28B oncogene can be addressed in these patients. Upregulation of LIN28B is shown to support the metastatic cascade.
Diana Corallo +8 more
wiley +1 more source
On the Scope of the Universal-Algebraic Approach to Constraint Satisfaction
The universal-algebraic approach has proved a powerful tool in the study of the complexity of CSPs. This approach has previously been applied to the study of CSPs with finite or (infinite) omega-categorical templates, and relies on two facts.
Bodirsky, Manuel +2 more
core +2 more sources
The novelty of this study showed that the injection of exosomes produced from ADMSCs in combination with Roflumilast poses a more favorable therapeutic outcome for CKD induced by Adriamycin, compared to therapy with exosomes or Roflumilast alone. Roflumilast and exosomes treatment lowered the expression of the apoptotic, fibrotic, and inflammatory ...
Mohamed Ali +5 more
wiley +1 more source
The Complexity of Phylogeny Constraint Satisfaction Problems
We systematically study the computational complexity of a broad class of computational problems in phylogenetic reconstruction. The class contains for example the rooted triple consistency problem, forbidden subtree problems, the quartet consistency ...
Bodirsky, Manuel +2 more
core +1 more source
The stability criteria affecting the formation of high‐entropy alloys, particularly focusing in supersaturated solid solutions produced by mechanical alloying, are analyzed. Criteria based on Hume–Rothery rules are distinguished from those derived from thermodynamic relations. The formers are generally applicable to mechanically alloyed samples.
Javier S. Blázquez +5 more
wiley +1 more source
Molecular dynamics simulations are advancing the study of ribonucleic acid (RNA) and RNA‐conjugated molecules. These developments include improvements in force fields, long‐timescale dynamics, and coarse‐grained models, addressing limitations and refining methods.
Kanchan Yadav, Iksoo Jang, Jong Bum Lee
wiley +1 more source
Experiments for reinforcing the diffusion bonding plane by the oxide dispersion strengthening effect are presented. Small ceramic particles (0.5 and 50 μm, respectively) are incorporated. Furthermore, ceramic particles help to penetrate stable passivation layers, enabling atomic diffusion across bonding planes. Since a ceramic–metallic interface cannot
Thomas Gietzelt +4 more
wiley +1 more source
List homomorphism problems for signed graphs
We consider homomorphisms of signed graphs from a computational perspective. In particular, we study the list homomorphism problem seeking a homomorphism of an input signed graph $(G,\sigma)$, equipped with lists $L(v) \subseteq V(H), v \in V(G)$, of ...
Bok, Jan +4 more
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