Results 91 to 100 of about 249,399 (261)

Artificial Intelligence in Systemic Sclerosis: Clinical Applications, Challenges, and Future Directions

Arthritis Care &Research, EarlyView.
Systemic sclerosis (SSc) is a rare autoimmune disease defined by immune dysregulation, vasculopathy, and progressive fibrosis of the skin and internal organs. Despite advances in care, major complications such as interstitial lung disease (ILD) and myocardial involvement remain the leading causes of morbidity and mortality.
Cristiana Sieiro Santos, José Miguel Sequí‐Sabater, Diego Benavent   +2 more
wiley   +1 more source

Transient receptor potential channel polymorphisms are associated with the somatosensory function in neuropathic pain patients. [PDF]

, 2011
Transient receptor potential channels are important mediators of thermal and mechanical stimuli and play an important role in neuropathic pain. The contribution of hereditary variants in the genes of transient receptor potential channels to neuropathic ...
Maihöfner Christian, Magerl Walter, Zhu, Jihong, Cascorbi Ingolf, Roman Rolke, Maihöfner, Christian, Binder Andreas, Treede, Rolf-Detlef, Faltraco, Frank, Flor, Herta, Rolf-Detlef Treede, Richter Helmut, Thomas R. Tölle, Nurcan Uçeyler, Huge, Volker, Mike Ufer, Christian Maihöfner, May, Denisa, Andrea Scherens, Uçeyler, Nurcan, Ralf Baron, May Denisa, Huge Volker, Cascorbi, Ingolf, Scherens, Andrea, Ufer, Mike, Gunnar Wasner, Binder, Andreas, Jihong Zhu, Herta Flor, Volker Huge, Helmut Richter, Tölle, Thomas R., Maier Christoph, Maier, Christoph, Thomas R Tölle, Tölle Thomas R., Zhu Jihong, Achim Berthele, Gierthmühlen Janne, Baron Ralf, Faltraco Frank, Magerl, Walter, Andreas Binder, Gierthmühlen, Janne, Christoph Maier, Richter, Helmut, Flor Herta, Wasner Gunnar, Denisa May, Scherens Andrea, Baron, Ralf, Üçeyler Nurcan, Haenisch Sierk, Rolke, Roman, Berthele Achim, Frank Faltraco, Ingolf Cascorbi, Berthele, Achim, Treede Rolf-Detlef, Ufer Mike, Haenisch, Sierk, Wasner, Gunnar, Janne Gierthmühlen, Sierk Haenisch, Rolke Roman, Walter Magerl, Binder, A;May, D;Baron, R;Maier, C;Tölle, TR;Treede, RD;Berthele, A;Faltraco, F;Flor, H;Gierthmühlen, J;Haenisch, S;Huge, V;Magerl, W;Maihöfner, C;Richter, H;Rolke, R;Scherens, A;Üçeyler, N;Ufer, M;Wasner, G;Zhu, J;Cascorbi, I   +67 more
core   +1 more source

Germline PDCDL1 Gene Variants Are Associated with Increased Primary Melanoma Thickness

Biomolecules
Background: The incidence of malignant melanoma (MM) continues to increase annually, and tumour invasiveness is a main prognostic factor. Single-nucleotide polymorphisms (SNPs) have become key tools in the study of cancer genetics, influencing ...
Elizabeth Córdoba-Lanús, Omar García-Pérez, Leticia Melgar-Vilaplana, Angélica Domínguez-de-Barros, Ricardo Fernández-de-Misa   +4 more
doaj   +1 more source

From Adult to Adolescent: Alignment in Clinical Trials and Outcomes in Axial Spondyloarthritis

Arthritis Care &Research, EarlyView.
Spondyloarthritis (SpA) is a group of chronic inflammatory diseases encompassing axial and peripheral forms, with up to 20% of patients developing symptoms before age 16. Despite this substantial pediatric burden, treatment options for juvenile‐onset SpA (JSpA), particularly those with axial disease (axJSpA), remain limited.
Pamela F. Weiss, Judith A. Smith, Robert A. Colbert, Erin Treemarcki, Michael H. Weisman, Walter P. Maksymowych, Hermine I. Brunner, for the Childhood Arthritis and Rheumatology Research Alliance, Spondyloarthritis Research and Treatment Network, and Pediatric Rheumatology Collaborative Study Group Advisory Council   +9 more
wiley   +1 more source

Unifying candidate gene and GWAS Approaches in Asthma. [PDF]

, 2010
The first genome wide association study (GWAS) for childhood asthma identified a novel major susceptibility locus on chromosome 17q21 harboring the ORMDL3 gene, but the role of previous asthma candidate genes was not specifically analyzed in this GWAS ...
Heinzmann, Andrea, Ruether, Andreas, Otto Laub, Bufe, A., Lathrop, M, Schedel, M., Michel, Sven, Ruether, A., Michel, S., Schreiber, Stefan, von Berg, A., Gut, I.G., Christian Vogelberg, Ernst Rietschel, von Mutius, E., Burkhard Simma, Schreiber, S., Klopp, N., Schedel, Michaela, Depner, Martin, Laub, O., Liang, Liming, Stefan Schreiber, Illig, T., Rietschel, E., Michael Kabesch, Gut, Ivo Glynne, Mutius, Erika von, Frischer, T., Kabesch, Michael, Kabesch, M., Lathrop, Mark, Frischer, Thomas, Ashish Kumar, Jon Genuneit, Gut, Ivo G., Albrecht Bufe, Mark Lathrop, Kumar, A., Rietschel, Ernst, Ivo G. Gut, Illig, Thomas, Martin Depner, Liming Liang, Heinzmann, A., Andrea von Berg, Laub, Otto, Thomas Illig, Andreas Ruether, Simma, B., Vogelberg, Christian, Bufe, Albrecht, Erika von Mutius, Simma, Burkhard, Ivo G Gut, Kumar, Ashish, Sven Michel, Liang, L.M., Depner, M., Berg, Andrea von, Thomas Frischer, Michaela Schedel, Genuneit, J., Genuneit, Jon, Vogelberg, C., Norman Klopp, Klopp, Norman, Andrea Heinzmann, Liang Liming, Schedel Michaela, Schreiber Stefan, Ruether Andreas, Depner Martin, Kabesch Michael, Simma Burkhard, Gut Ivo G., Illig Thomas, von Berg Andrea, Kumar Ashish, Frischer Thomas, Laub Otto, Rietschel Ernst, Heinzmann Andrea, Klopp Norman, Michel Sven, Bufe Albrecht, von Mutius Erika, Genuneit Jon, Lathrop Mark, Vogelberg Christian   +89 more
core   +2 more sources

Effect Modification of Cigarette Smoking on the Relationship Between Posttraumatic Stress Disorder, Other Mental Health Conditions, and Rheumatoid Arthritis Risk: A Large Case‐Control Study in US Veterans

Arthritis Care &Research, EarlyView.
Objective We examined associations of posttraumatic stress disorder (PTSD) and other mental health disorders (OMH) with rheumatoid arthritis (RA), accounting for effects of smoking. Methods We conducted a matched case‐control study, identifying incident RA cases and controls using national Veterans Health Administration data (2006–2019).
Kelsey Coziahr, Harlan Sayles, Tate M. Johnson, Joshua F. Baker, Punyasha Roul, Grant W. Cannon, Gary A. Kunkel, Katherine D. Wysham, Gail S. Kerr, Amir A. Razmjou, Isaac Smith, Jennifer L. Barton, Maria I. Danila, Jonathan S. Richards, Bryant R. England, Ted R. Mikuls   +15 more
wiley   +1 more source

CYP2D6 polymorphisms and their influence on risperidone treatment

, 2016
Apichaya Puangpetch,1 Natchaya Vanwong,1 Nopphadol Nuntamool,2 Yaowaluck Hongkaew,1 Monpat Chamnanphon,1 Chonlaphat Sukasem1 1Division of Pharmacogenomics and Personalized Medicine, Department of Pathology, Faculty of Medicine Ramathibodi Hospital ...
Puangpetch A, Hongkaew Y, Chamnanphon M, Sukasem C, Nuntamool N, Vanwong N   +5 more
core  

A population-based study of glutathione-S-transferase M1, T1 and P1 genotypes [PDF]

, 2008
A retrospective study on healthy, unrelated subjects was conducted in order to estimate population glutathione-S-transferases (GST) genotype frequencies in Slovak population of men and compare our results with already published data (GSEC project)^1^.
Monika Sivoňová, Tatiana Matáková, Iveta Waczulíková, Peter Račay, Dušan Dobrota, Jozef Hatok, Ján Kliment   +6 more
core  

Revisiting Stability Criteria in Ball‐Milled High‐Entropy Alloys: Do Hume–Rothery and Thermodynamic Rules Equally Apply?

Advanced Engineering Materials, Volume 27, Issue 6, March 2025.
The stability criteria affecting the formation of high‐entropy alloys, particularly focusing in supersaturated solid solutions produced by mechanical alloying, are analyzed. Criteria based on Hume–Rothery rules are distinguished from those derived from thermodynamic relations. The formers are generally applicable to mechanically alloyed samples.
Javier S. Blázquez, Alejandro F. Manchón‐Gordón, Antonio Vidal‐Crespo, Rafael Caballero‐Flores, Jhon J. Ipus, Clara F. Conde   +5 more
wiley   +1 more source

Bladder Cancer and Genetic Polymorphisms: A Review [PDF]

, 2015
The aetiology of bladder cancer (BC) is still not fully understood. Genetic factors and many different pathways could be involved in the formation and progression of the BC.
Yavuz Onur Danacıoglu, Turhan Çaşkurlu, Bulent Erol, Ismail Ulus   +3 more
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