Advanced Science, EarlyView.Aldosterone‐producing adenomas (APAs) develop via two distinct paths: directly from adrenal zona glomerulosa (zG) cells, or stepwise from zG cells through aldosterone‐producing micronodules (APMs) before progressing to APAs. Advanced single‐cell and spatial analyses identified distinct cell states linked to oxidative stress and cell–cell interactions ...
Zhuolun Sun +7 more
wiley +1 more source
Tracking karyotype dynamics by flow cytometry reveals de novo chromosome duplications in laboratory cultures of Macrostomum lignano. [PDF]
Biol OpenMouton S, Glazenburg L, Berezikov E.
europepmc +1 more source
Nicotine oxidation by genetic variants of CYP2B6 and in human brain microsomes [PDF]
, 2019 Bloom, Adam Joseph +2 more
core +2 more sources
Hyperelastic Starch Hydrogel Configures Edible and Biodegradable All‐Components for Soft Robots
Advanced Science, EarlyView.Hyperelastic starch hydrogel is tailored via a phase separation strategy of solvent‐antisolvent co‐modulation. The mechanical performance of starch hydrogel is widely tuned with maximum strains: 194.4–361.4%; maximum tensile stresses: 34–192 kPa; and Young's moduli: 36.0–205.8 kPa. Notably, the hydrogel achieves complete soil degradation within 24 days
Siyu Yao +7 more
wiley +1 more source
Top‐Down Fabricated Wood‐Derived Pressure and Strain Sensors: A Review
Advanced Science, EarlyView.This review focuses on wood‐derived pressure/strain sensors fabricated via top‐down strategies. It analyzes wood's structural composition, examines processing techniques, discusses sensor types and sensing mechanisms, and reviews existing research. The article concludes with future directions for enhancing performance and scalability.
Yi Ren +8 more
wiley +1 more source
Advanced Science, EarlyView.Researchers have developed a patient‐derived organ‐on‐a‐chip model for pancreatic cancer by integrating cancer cells with supportive stromal and immune cells inside a microfluidic device. This system mimics the tumor microenvironment, enabling personalized testing of chemotherapy and immunotherapy, and offering new insights into how targeting ...
Darbaz Adnan +11 more
wiley +1 more source
The potential of cytokine polymorphisms as biomarkers for oral squamous cell carcinoma: a systematic review. [PDF]
Discov OncolMfengu MOM +3 more
europepmc +1 more source
Genomics Insights Into High‐Latitude Adaptation of Tibetan Macaques
Advanced Science, EarlyView.Tibetan macaques exhibit unique adaptations to cold, high‐latitude environments, including shortened tails and enhanced fat storage. Genomic analyses reveal a species‐specific TBX6 mutation linked to tail reduction and selection on lipid metabolism genes.
Rusong Zhang +12 more
wiley +1 more source
Leptin receptor rs1137101 polymorphism and altered leptin-sOb-R axis contribute to type 2 diabetes risk in Gujarat population. [PDF]
Front Endocrinol (Lausanne)Parmar N +8 more
europepmc +1 more source
A paraoxonase gene polymorphism, PON 1 (55), as an independent risk factor for increased carotid intima-media tickness in middle-aged women. [PDF]
, 2003 DE MICHELE M +10 more
core