Advanced Science, EarlyView.This work introduces a multimodal multi‐OoC platform that overcomes current limitations in liver‐tumor interaction studies and prodrug screening. By integrating dynamic microfluidic circuits, electrochemical sensing, and mass analysis, this platform enables non‐invasive, longitudinal monitoring of drug metabolism and hepatotoxicity, offering a ...
Dan Wang +10 more
wiley +1 more source
BDNF genetic variants modulate the impact of childhood trauma on symptom dimensions in first-episode schizophrenia. [PDF]
Front PsychiatryPing J +5 more
europepmc +1 more source
Heterointerface‑Enabled Electrocatalysis for Efficient Energy Conversion
Advanced Science, EarlyView.Functionally distinct A/B materials can be integrated at the nanoscale to create customized heterointerfaces with tunable band alignment and charge redistribution, providing fast electron and ion transport channels as well as cooperative dual active sites.
Liuru Fang +3 more
wiley +1 more source
Distribution of Thrombophilia-Related Genetic Polymorphisms in Women with Reproductive Disorders. [PDF]
BiomedicinesKurmanova A +9 more
europepmc +1 more source
A paraoxonase gene polymorphism, PON 1 (55), as an independent risk factor for increased carotid intima-media tickness in middle-aged women. [PDF]
, 2003 DE MICHELE M +10 more
core
SDS‐CRISPR for Single‐Nucleotide Variant Detection
Advanced Science, EarlyView.Structure‐disruption‐sensitive CRISPR (SDS‐CRISPR) converts structural instability into single‐nucleotide precision, thereby overcoming mismatch tolerance in canonical Cas12a and enabling versatile diagnostics across DNA, RNA, and microRNA targets. When applied to rapid IDH1 mutation detection for glioma genotyping and integrated with lateral‐flow ...
Xin Guan +12 more
wiley +1 more source
Role of IL-6 gene polymorphisms in children with autism spectrum disorders. [PDF]
Ital J PediatrAbdullah NM +5 more
europepmc +1 more source
Nanoplastics and Neurodegeneration: A Roadmap From Mechanism to Causation
Advanced Science, EarlyView.Nanoplastics are pervasive environmental contaminants with potentially profound implications for human health. Emerging evidence suggests a possible link between nanoplastic exposure and neurodegeneration, a key driver of ageing and dementia, yet causality remains unresolved.
Yuhuan Li +5 more
wiley +1 more source
Vitamin D and melanoma: an umbrella meta-analysis of serum levels, dietary intake, and VDR polymorphisms. [PDF]
J Transl MedJiang B +5 more
europepmc +1 more source
Advanced Science, EarlyView.This review systematically explores the recent advances in in situ polymerized composite polymer electrolytes (CPEs) for solid‐state lithium batteries. It covers the fundamentals of reaction mechanisms, monomer chemistry, and their impact on interfacial stability, ionic conductivity, and electrochemical performance.
Jialin Li +9 more
wiley +1 more source