Results 71 to 80 of about 16,231 (238)
Design of the Tocilizumab in Giant Cell Arteritis Trial [PDF]
, 2013 Overview. The GiACTA trial is a multicenter, randomized, double-blind, and placebo-controlled study designed to test the ability of tocilizumab (TCZ), an interleukin (IL)-6 receptor antagonist, to maintain disease remission in patients with giant cell ...
Dasgupta, Bhaskar +8 more
core +3 more sources
Expert Perspective: Hematologic Malignancies and Vasculitis
Arthritis &Rheumatology, EarlyView.
Michelle L. Robinette, Hetty E. Carraway
wiley +1 more source
The Journal of Clinical Pharmacology, Volume 65, Issue 7, Page 895-908, July 2025.Abstract Compared to traditional small molecule drugs, monoclonal antibodies (mAbs) often display more complex pharmacokinetic (PK) and pharmacodynamic (PD) properties that may be impacted by disease‐specific factors. For mAbs in non‐oncology indications, where the same drug might be used for conditions involving different organ systems and/or having ...
Sherouk M. Tawfik, Fei Tang
wiley +1 more source
Journal of the American Heart Association: Cardiovascular and Cerebrovascular DiseaseBackground Autoimmune diseases are closely linked to cardiovascular diseases. This study aimed to assess the relationship between cardiovascular health (CVH) defined by Life's Essential 8 (LE8), genetic predisposition, and the risk of 19 autoimmune ...
Lijin Lin +8 more
doaj +1 more source
Prevalence of Frailty and Associated Factors in a US‐Wide Cohort of Rheumatic Diseases
ACR Open Rheumatology, Volume 7, Issue 6, June 2025.Objective We quantified the prevalence of self‐reported frailty and identified associated factors in a US‐wide cohort of people with rheumatic and musculoskeletal diseases (RMDs). Methods Frailty was measured using the FRAIL scale, a patient‐reported frailty instrument, in FORWARD, The US‐based National Databank for Rheumatic Diseases.
Katherine D. Wysham +10 more
wiley +1 more source
Musculoskeletal Care, Volume 23, Issue 2, June 2025.ABSTRACT Objective To evaluate the impact of home working on the psychological well‐being of European patients with Rheumatic and Musculoskeletal Diseases (RMDs) during the COVID‐19 pandemic. Methods REUMAVID is a cross‐sectional study that collected data through an online survey in seven European countries during the COVID‐19 pandemic: Phase 1 (April ...
Marco Garrido‐Cumbrera +4 more
wiley +1 more source
Induction of Remission is Difficult due to Frequent Relapse during Tapering Steroids in Korean Patients with Polymyalgia Rheumatica [PDF]
, 2012 Polymyalgia rheumatica is an inflammatory disease affecting elderly and involving the shoulder and pelvic girdles. No epidemiological study of polymyalgia rheumatica was conducted in Korea.
Bird +43 more
core +2 more sources
Pediatric Blood &Cancer, Volume 72, Issue 6, June 2025.ABSTRACT Background Hematopoietic stem cell transplantation (HCT) is a potentially curative treatment for children with hematological or immunological disorders. However, treatment‐related morbidity and mortality remain concerning. Various comorbidity indices are currently used to assess the risk of complications following pediatric HCT.
Roos Lotte Alexandra Bukman +4 more
wiley +1 more source
SAGE Open Medical Case ReportsMessenger ribonucleic acid-based vaccines that target severe acute respiratory syndrome coronavirus 2 have shown high effectiveness. While these Coronavirus Disease 2019 vaccines have a favorable safety profile, there can be rare adverse drug reactions ...
Kosuke Matsuzono, Shigeru Fujimoto
doaj +1 more source
Alendronate or alfacalcidol in glucocorticoid-induced osteoporosis [PDF]
, 2006 BACKGROUND: Treatment with glucocorticoids is associated with bone loss starting soon after therapy is initiated and an increased risk of fracture. METHODS: We performed a randomized, double-placebo, double-blind clinical trial of 18 months' duration ...
Ale Algra +14 more
core +4 more sources