Results 161 to 170 of about 6,612 (269)

TrkA abundance is increased in cutaneous nerves in bortezomib‐induced neuropathy

Brain Pathology, Volume 36, Issue 4, July 2026.
Cutaneous nerves in bortezomib‐induced peripheral neuropathy (BIPN) show reduced nerve fiber density, increased TrkA expression, and enhanced dermal angiogenesis, highlighting a pathological switch in NGF/TrkA signaling that may contribute to nerve damage and pain. Abstract Tropomyosin receptor kinase A (TrkA), a high‐affinity receptor for nerve growth
Yuying Jin, Nadine Cebulla, Daniel Schirmer, Eva Runau, Leon Flamm, Calvin Terhorst, Laura Jähnel, Johanna Güse, Nicola Giordani, Annett Wieser, Julian Brennecke, Annemarie Sodmann, Martin Kortüm, Robert Blum, Claudia Sommer   +14 more
wiley   +1 more source

Genome-wide meta-analysis identifies genetic risk loci for mono- and polyneuropathies in 983 477 individuals. [PDF]

Hum Mol Genet
Broberg M, Gen F, Kalso E, Ollila HM.
europepmc   +1 more source

Optimising the Therapeutic Window: A Systematic Review and Network Meta‐Analysis of Pregabalin Dosing Strategies for Painful Diabetic Neuropathy

Diabetes, Obesity and Metabolism, Volume 28, Issue 7, Page 5637-5648, July 2026.
ABSTRACT Aims Although pregabalin is a first‐line therapy for painful diabetic polyneuropathy (PDPN), its optimal dose–response relationship remains unclear. We conducted a network meta‐analysis to evaluate the efficacy and safety of fixed pregabalin dosages in PDPN patients.
Doyun Kwon, Hee‐Jae Jung, Junho Nam, Jonghae Kim, Eonju Jeon, Sanggyu Kwak   +5 more
wiley   +1 more source

Neuropsychiatric adverse events of SGLT2 inhibitors: a pharmacovigilance analysis of the FDA adverse event reporting system database. [PDF]

Front Med (Lausanne)
Yin M, Tan H, Xie S, Kuang Y, Wu Q, Ma J, Guo C.   +6 more
europepmc   +1 more source

Bifidobacterium bifidum G9‐1 Intake Improves Gastrointestinal Symptoms in Type 2 Diabetes Mellitus: An Open‐Label, Randomized Controlled Trial (Binary STAR Study)

Diabetes, Obesity and Metabolism, Volume 28, Issue 7, Page 5952-5967, July 2026.
ABSTRACT Aims To evaluate the effects of probiotics Bifidobacterium bifidum G9‐1 (BBG9‐1) on gastrointestinal symptoms in patients with Type 2 diabetes mellitus (T2DM) with diarrhoea or constipation. Materials and Methods In a 12‐week open‐label randomised controlled trial, 100 participants were randomized 1:1 to a control or BBG9‐1 group, with 12 mg ...
Genki Kobayashi, Yoshitaka Hashimoto, Tomoyuki Matsuyama, Noriyuki Kitagawa, Saori Majima, Takafumi Senmaru, Emi Ushigome, Hiroshi Okada, Naoko Nakanishi, Masahide Hamaguchi, Michiaki Fukui   +10 more
wiley   +1 more source

Electrophysiological-based automatic subgroups diagnosis of patients with chronic dysimmune polyneuropathies. [PDF]

J Neuroeng Rehabil
Ballanti S, Liuzzi P, Mattiolo PL, Scarpino M, Matà S, Hakiki B, Cecchi F, Oddo CM, Mannini A, Grippo A.   +9 more
europepmc   +1 more source

FREQUENCY AND DIAGNOSTIC FEATURES OF CRANIAL POLYNEUROPATHIES ASSOCIATED WITH COVID-19

Currently, 45% of patients who have recovered from COVID-19 face neurological disorders. These complications range from neurasthenia to severe conditions such as brain ischemia, encephalomyelitis, encephalopathy, and polyneuropathies (damage to the ...
Kamolov G. K., Khonnazarov U. Kh.
core  

Plantar fascia thickness in type 1 diabetes mellitus patients: Clinical associations and metabolic correlates

Journal of Diabetes Investigation, Volume 17, Issue 7, Page 1210-1217, July 2026.
Ultrasound‐measured plantar fascia thickness is associated with microvascular complications and glycemic control in individuals with type 1 diabetes, suggesting PFT as a potential non‐invasive tool for clinical assessment. In addition, improved thickness values were observed in patients using automated insulin delivery systems.
Giulia Casadei, Michele Baldari, Lorenzo Brognara, Enrico Saudelli, Simona Moscatiello, Sara Flamigni, Francesco Traina, Alexandro Paccapelo, Uberto Pagotto, Guido Di Dalmazi   +9 more
wiley   +1 more source

Hereditary Polyneuropathies in the Era of Precision Medicine: Genetic Complexity and Emerging Strategies. [PDF]

Genes (Basel)
Chrysostomaki M, Chatzi D, Kyriakoudi SA, Meditskou S, Manthou ME, Gargani S, Theotokis P, Dermitzakis I.   +7 more
europepmc   +1 more source

Body mass index and peripheral neuropathy across the glucose tolerance spectrum in Japanese adults

Journal of Diabetes Investigation, Volume 17, Issue 7, Page 1142-1153, July 2026.
Graphical illustration of participant classification by metabolic status (normoglycemic, IGT, type 2 diabetes mellitus) and BMI with key neurological and metabolic assessments. In Japanese adults, obesity at the Japanese BMI threshold (≥25 kg/m2) is associated with adverse metabolic profiles across all glycemic states but exacerbates peripheral ...
Fukashi Ishibashi, Aiko Kosaka, Harumi Uetake, Darren C. Greenwood, Laura Güdemann, Hassan Fadavi, Mitra Tavakoli   +6 more
wiley   +1 more source