Results 121 to 130 of about 72,493 (257)

Kidney Outcomes With GLP‐1 Receptor Agonists and Tirzepatide Versus Finerenone in Type 2 Diabetes and Chronic Kidney Disease: A Real‐World Cohort Study

Diabetes, Obesity and Metabolism, EarlyView.
ABSTRACT Aim To compare kidney outcomes after GLP‐1 receptor agonists (RA) or tirzepatide (GLP‐1/GIP RAs) versus finerenone initiation in adults with Type 2 diabetes (T2D) and moderate chronic kidney disease (CKD). Methods In a retrospective TriNetX global network study (July 2021–November 2025), adults with T2D and CKD stages 3–4 initiating GLP‐1/GIP ...
Dvora R. Sehtman‐Shachar, Alisa Fishkin, Gil Leibowitz, Ofri Mosenzon, Meir Schechter, Genya Aharon‐Hananel   +5 more
wiley   +1 more source

Prevalence and Disability of Peripheral Neuropathy in Patients With Waldenström's Macroglobulinemia

European Journal of Haematology, EarlyView.
ABSTRACT Objectives Peripheral neuropathy (PN) is considered a frequent complication of Waldenström's macroglobulinemia (WM). Establishing a causal relationship between PN and WM is complicated by confounding factors such as age‐related axonal loss and diabetes. This scoping review aims to summarize the current evidence on WM‐associated PN with a focus
Morten Müller Aagaard, Kristoffer Nagy Skaastrup, Louise Sloth Kodal, Britt Stævnsbo Pedersen, Troels Hammer, John Vissing, Tina Dysgaard   +6 more
wiley   +1 more source

Persistent in vitro nociceptor hyperexcitability and axonal retraction produced by repeated paclitaxel doses

The FEBS Journal, EarlyView.
Repeated paclitaxel exposure causes long‐lasting nociceptor hyperexcitability and axonal retraction in adult sensory neurons. Using a long‐term primary nociceptor culture, we show that hyperexcitability is mediated by sequential upregulation of NaV1.8, TRPV1, TRPA1, and TRPM8 channels.
Angela Lamberti, Victor Moreno Lozano, Asia Fernández‐Carvajal, Antonio Ferrer‐Montiel   +3 more
wiley   +1 more source

Vitamin B6: too much, too little, too late? An analysis of sales trends in Australia from 2023 to 2025

Internal Medicine Journal, EarlyView.
Abstract Background Peripheral neuropathy associated with vitamin B6 (pyridoxine) is dose and duration dependent. High‐dose vitamin B6 products associated with adverse neurological effects are available in Australia, prompting recent regulatory action to reschedule products containing ≥50 mg pyridoxine to schedule 3 (pharmacist only).
Wai‐Jo Jocelin Chan, Jennifer Hunter, Vivian Yeukman Lee, Rose Cairns, Slade Mathews, Joanna E. Harnett   +5 more
wiley   +1 more source

Clinical and Neurophysiologic Features in Paraneoplastic Polyneuropathy

, 1988
Three of 8,954 in- patients have been selected as affected by paraneoplastic polyneuropathy. In all of them the polyneuropathy had a steadily progressive course, with symptoms beginning in the lower limbs and spreading to the upper limbs in a few months.
Ornella Strada, Giorgio Valli, Carlo Pirovano   +2 more
core   +1 more source

SGLT2i use and fracture risk compared with DPP4i in patients with T2DM

Journal of Diabetes Investigation, EarlyView.
ABSTRACT Introduction The association between sodium‐glucose cotransporter‐2 inhibitor (SGLT2i) use and fracture risk remains inconclusive. Most previous studies have focused on treatment‐naïve patients, despite many patients in routine clinical practice initiating SGLT2i therapy after prior dipeptidyl peptidase‐4 inhibitor (DPP4i) use.
Sung‐Yen Lin, Shih‐Hao Huang, Ching‐Han Chiang, Cheng‐Jung Ho, Chung‐Hwan Chen, Li‐Nien Chien   +5 more
wiley   +1 more source

Diagnostic Performance of the Strength-Duration Test for Bedside Screening of Critical Illness Polyneuropathy and/or Myopathy: A Prospective, Cross-Sectional Study. [PDF]

Muscle Nerve
ABSTRACT Introduction/Aims Critical illness polyneuropathy and/or myopathy (CIP/CIM) is a major cause of weakness in the intensive care unit (ICU). The availability of conventional electrodiagnostic testing may be limited. Alternative electrophysiologic methods, including the strength‐duration test (SDT) and the stimulus electrodiagnosis test (SET ...
Macedo JRD, Fachin-Martins E, Rodrigues MM, de Carvalho MR, Fernandez RNM, Silva PE.   +5 more
europepmc   +2 more sources

Chlorpyrifos-induced delayed polyneuropathy

, 1991
Chlorpyrifos [0,0-diethyl 0-(3,5,6-trichloro-pyridyl) phosphorothioate] caused delayed polyneuropathy in man. Contrary to previous studies, we report here that it also causes delayed polyneuropathy in the hen, the animal model for this toxicity.
M. Lotti, A. Moretto, S. Caroldi, CAPODICASA E, LOTTI, MARCELLO, SCAPELLATO ML, CAROLDI S, M. L. Scapellato, MORETTO A, E. Capodicasa   +9 more
core   +1 more source

Polyneuropathy - Treatment [PDF]

DMW - Deutsche Medizinische Wochenschrift, 2002
B, Schlotter-Weigel, D E, Pongratz
openaire   +2 more sources

Epidermal necrolysis sequelae: A cohort study on prevalence and risk factors

Journal of the European Academy of Dermatology and Venereology, EarlyView.
Long‐term sequelae after epidermal necrolysis are frequent, multiple and often severe. Cutaneous, ocular and psychological complications are more frequent, with significant socioeconomic impact. Cluster analysis identifies distinct patient profiles, highlighting the need for personalized multidisciplinary follow‐up.
Thanh Vy Nguyen, Thomas Bettuzzi, Karim Zaghbib, Julie Gueudry, Audrey Colin, Kmar Bel Hareth, Narimane Terkmane, Emilie Sbidian, Nicolas de Prost, Saskia Ingen‐Housz‐Oro   +9 more
wiley   +1 more source