Evaluating Performance of Machine Learning Models for Diabetic Sensorimotor Polyneuropathy Severity Classification using Biomechanical Signals during Gait [PDF]
arXiv, 2022 Diabetic sensorimotor polyneuropathy (DSPN) is one of the prevalent forms of neuropathy affected by diabetic patients that involves alterations in biomechanical changes in human gait. In literature, for the last 50 years, researchers are trying to observe the biomechanical changes due to DSPN by studying muscle electromyography (EMG), and ground ...
arxiv
Polyneuropathy: A Rare and Challenging Presentation of Essential Mixed Cryoglobulinemia
Journal of Investigative Medicine High Impact Case Reports, 2021 A 49-year-old male presented with acute chronic sensory motor bilateral lower extremity polyneuropathy. Electromyography showed bilateral acute sensory motor axonal polyneuropathy.
Ahmed Taha MD +5 more
doaj +1 more source
Study of the Parent-of-origin effect in monogenic diseases with variable age of onset. Application on ATTRv [PDF]
arXiv, 2021 In genetic diseases with variable age of onset, an accurate estimation of the survival function for the mutation carriers and also modifying factors effects estimations are important for the management of asymptomatic gene carriers across life. Among the modifying factors, the gender of the parent transmitting the mutation (i.e.
arxiv
Guillain-Barré syndrome: a century of progress [PDF]
, 2016 In 1916, Guillain, Barré and Strohl reported on two cases of acute flaccid paralysis with high cerebrospinal fluid protein levels and normal cell counts — novel findings that identified the disease we now know as Guillain–Barré syndrome (GBS).
A Campbell +91 more
core +1 more source
Journal of Rehabilitation Medicine, 2022 Patients with COVID-19 may develop a range of neurological disorders. We report here 4 COVID-19 subjects with intensive care unit-acquired weakness and their functional outcome.
Domenico Intiso +5 more
doaj +1 more source
A novel hotspot of gelsolin instability and aggregation propensity triggers a new mechanism of amyloidosis [PDF]
arXiv, 2021 The multidomain protein gelsolin (GSN) is composed of six homologous modules, sequentially named G1 to G6. Single point substitutions in this protein are responsible for AGel amyloidosis, a hereditary disease characterized by progressive corneal lattice dystrophy, cutis laxa, and polyneuropathy. Several different amyloidogenic variants of GSN have been
arxiv
Canine NAPEPLD-associated models of human myelin disorders [PDF]
, 2018 Canine leukoencephalomyelopathy (LEMP) is a juvenile-onset neurodegenerative disorder of the CNS white matter currently described in Rottweiler and Leonberger dogs. Genome-wide association study (GWAS) allowed us to map LEMP in a Leonberger cohort to dog
Bannasch, D L +28 more
core +5 more sources
NGX-4010, a capsaicin 8% patch, for the treatment of painful HIV-associated distal sensory polyneuropathy: integrated analysis of two phase III, randomized, controlled trials [PDF]
, 2013 BACKGROUND HIV-associated distal sensory polyneuropathy (HIV-DSP) is the most frequently reported neurologic complication associated with HIV infection.
Brew, Bruce J +9 more
core +1 more source
Neuromodulation: Technology at the Neural Interface, EarlyView., 2021 Abstract Background Refractory chronic migraine (rCM) is a highly disabling condition for which novel safe and effective treatments are needed. Safety and long‐term efficacy of paresthesia‐free high cervical 10 kHz spinal cord stimulation (SCS) were here prospectively evaluated for the treatment of rCM.
Adnan Al‐Kaisy +7 more
wiley +1 more source
Correlates of diabetic polyneuropathy of the elderly in Sub-Saharan Africa.
PLoS ONE, 2020 BackgroundDiabetic polyneuropathy is associated with significant physical disability among older adults. However, their frequency and correlates are not well known in the older adults in Sub-Saharan-Africa.
Nadine Simo +8 more
doaj +1 more source