MetaboSense is a first‐of‐its‐kind microfluidic platform enabling continuous, in‐line monitoring of glucose and lactate during ex vivo lung perfusion. Combining a quantum dot–mediated aptamer assay with mixing, depletion, and optofluidic detection modules, it achieves 60–s temporal resolution and shows strong agreement with standard blood gas analyzers,
Sanjana Srikant +14 more
wiley +1 more source
Time-Optimal Trajectory Planning Method for Servo PMSM Based on Short-Term Dynamic Feasible Region Constraint. [PDF]
Li H +5 more
europepmc +1 more source
Polynomial time approximation schemes for Euclidean traveling salesman and other geometric problems
Sanjeev Arora
semanticscholar +1 more source
D-optimal Design for Polynomial Regression: Choice of Degree and Robustness [PDF]
In this paper we show that for D-optimal design, departures from the design are much less important than a depar-ture from a model. As a consequence, we propose, based on D-optimality, a rule for choosing the regression degree.
Weinberg Allen, Anna, Antille, Gerard
core
Inverse Design of Pre‐Strain via a Predictive Electromechanical Model for Enhanced Strain Sensing
An analytical electromechanical model rooted in microcrack evolution mechanics is globally calibrated from only eight pre‐strain datasets, enabling prediction of the complete sensing response at untested pre‐strain values within the calibrated design space (R2 > 0.99).
Jia‐Chen Shang +10 more
wiley +1 more source
Virtual-patient nonlinear mixed-effects modelling for data-driven optimisation of single-time-point dosimetry: a proof-of-concept study in [<sup>177</sup>Lu]Lu-PSMA-617 therapy. [PDF]
Pertiwi Y +7 more
europepmc +1 more source
Canonical Antibodies Adopt Distinct Binding Modes to Recognize Viral Glycan Shields
Canonical Y‐shaped antibodies recognize viral glycan shields through adaptive Fab assembly states shaped by glycan organization and somatic hypermutation. Structural analyses ofbroadly neutralizing antibodies VRC35 and VRC36 across glycoproteins of HIV‐1, influenza, SARS‐CoV‐2, and Lassa viruses reveal distinct Fab assembly states, spanning monovalent,
Jiaxuan Cheng +71 more
wiley +1 more source
Simulation-informed kernel-based regression models for predicting temperature distribution in microwave hyperthermia. [PDF]
Alazwari MA, Abu-Hamdeh NH, Almitani KH.
europepmc +1 more source
Fzd7 Restrains Pink1‐Dependent Mitophagy in Suture Stem Cells to Maintain Cranial Suture Patency
How suture stem cells fail to preserve cranial suture patency remains incompletely understood. Integrated single‐cell and high‐resolution spatial transcriptomic analyses identify reduced Fzd7 expression in Prrx1+ suture stem cells as an early feature of craniosynostosis.
Xinyan Chen +10 more
wiley +1 more source

