Results 191 to 200 of about 27,614 (213)

DNA intercalation of methylene blue and quinacrine: new insights into base and sequence specificity from structural and thermodynamic studies with polynucleotides.

Molecular Biosystems, 2009
The binding of the known DNA intercalators methylene blue and quinacrine with four sequence specific polynucleotides, viz. poly(dG-dC).poly(dG-dC), poly(dG).poly(dC), poly(dA-dT).poly(dA-dT) and poly(dA).poly(dT), have been compared using absorbance ...
Maidul Hossain, G. Suresh Kumar
semanticscholar   +1 more source

Determination of Free Energy Profiles for the Translocation of Polynucleotides through α-Hemolysin Nanopores using Non-Equilibrium Molecular Dynamics Simulations.

Journal of Chemical Theory and Computation, 2009
The translocation of polynucleotides through transmembrane protein pores is a fundamental biological process with important technological and medical relevance.
H. Martin, S. Jha, S. Howorka, P. Coveney   +3 more
semanticscholar   +1 more source

Cyclobutane-Type Pyrimidine Dimers in Polynucleotides

Science, 1966
The formation of cyclobutane-type dimers between adjacent pyrimidine residues in model polynucleotides or DNA may be represented by the general scheme See pdf 379.pdf Whereas the formation of all other known photoproducts follows the irreversible path ...
R. Setlow
semanticscholar   +1 more source

Evaluation of asymmetric liposomal nanoparticles for encapsulation of polynucleotides.

Langmuir, 2008
Conventional lipid bilayer liposomes have similar inner and outer leaflet compositions; asymmetric liposomes have different lipid leaflet compositions.
Jeremiah Whittenton, S. Harendra, R. Pitchumani, K. Mohanty, C. Vipulanandan, S. Thevananther   +5 more
semanticscholar   +1 more source

Absorption spectra of nucleotides, polynucleotides, and nucleic acids in the far ultraviolet

, 1963
Ultaviolet absorption spectra down to 185 mμ are presented for a number of nucleic acids and synthetic polynucleotides in the helical and random forms, and of their constituent mononucleotides, as well as the corresponding nucleosides and free bases.
D. Voet, W. Gratzer, R. A. Cox, P. Doty
semanticscholar   +1 more source

Hypochlorite-induced damage to DNA, RNA, and polynucleotides: formation of chloramines and nitrogen-centered radicals.

Chemical Research in Toxicology, 2002
Stimulated monocytes and neutrophils generate hypochlorite (HOCl) via the release of the enzyme myeloperoxidase and hydrogen peroxide. HOCl is a key bactericidal agent, but can also damage host tissue.
C. Hawkins, M. Davies
semanticscholar   +1 more source

HYPOCHROMISM AND OTHER SPECTRAL PROPERTIES OF HELICAL POLYNUCLEOTIDES

, 1961
Exciton interaction in a double-stranded helical polymer, such as a homogeneous polynucleotide, leads to a splitting of each excited electronic energy level of the monomer into two exciton bands of energy levels.
W. Rhodes
semanticscholar   +1 more source

Stereochemistry of nucleic acids and their constituents. IV. Allowed and preferred conformations of nucleosides, nucleoside mono‐, di‐, tri‐, tetraphosphates, nucleic acids and polynucleotides

, 1969
A uniform notation and convention is suggested to describe the torsional angles in nucleic acids and their derivatives. The torsional angle χ, relating the stereochemistry of the base with respect to the sugar, shows more variation for the β‐purine ...
M. Sundaralingam
semanticscholar   +1 more source

Direct covalent mercuration of nucleotides and polynucleotides.

Biochemistry, 1975
Nucleotides of cytosine and uracil are readily mercurated by heating at 37-50 degrees in buffered aqueous solutions (pH 5.0-8.0) containing mercuric acetate.
R. Dale, E. Martin, D. C. Livingston, D. Ward   +3 more
semanticscholar   +1 more source

Interactions of aromatic residues of proteins with nucleic acids. Fluorescence studies of the binding of oligopeptides containing tryptophan and tyrosine residues to polynucleotides.

Biochemistry, 1975
The binding of oligopeptides of general structure Lys-X-Lys (where X is an aromatic residue) to several polynucleotides has been studied by fluorescence spectroscopy.
F. Brun, J. Toulmé, C. Hélène
semanticscholar   +1 more source