Results 81 to 90 of about 6,390 (207)

Safety of an Intravitreal Bevacizumab Biosimilar (MVASI)

open access: yesClinical &Experimental Ophthalmology, Volume 53, Issue 5, Page 523-528, July 2025.
ABSTRACT Background Intravitreal bevacizumab has been used off‐label to treat multiple ocular conditions for almost two decades. Reference bevacizumab, Avastin, was discontinued in Australia in 2021. A bevacizumab biosimilar, MVASI, was approved by the Therapeutic Goods Administration for the treatment of metastatic cancer in 2020.
Hanru Wang   +8 more
wiley   +1 more source

Optimization and regeneration kinetics of lymphatic-specific photodynamic therapy in the mouse dermis. [PDF]

open access: yes, 2013
Lymphatic vessels transport fluid, antigens, and immune cells to the lymph nodes to orchestrate adaptive immunity and maintain peripheral tolerance. Lymphangiogenesis has been associated with inflammation, cancer metastasis, autoimmunity, tolerance and ...
Golab, J.   +6 more
core   +1 more source

Assistance of Artificial Intelligence in Diagnosis of Vitreoretinal Lymphoma on Optical Coherence Tomography

open access: yesAdvanced Intelligent Systems, Volume 7, Issue 4, April 2025.
The proposed artificial intelligence model, cross‐subject meta‐transfer learning, enables the automatic detection of vitreoretinal lymphoma (VRL) on optical coherence tomography images among 16 retinal diseases and conditions. This study provides an innovative solution to assist in the VRL diagnosis in real‐world clinical implementation, showing ...
Aidi Lin   +23 more
wiley   +1 more source

Elastin Variants in Two Angiographic PCV Subtypes [PDF]

open access: yes, 2021
Objective To compare the association of elastin (ELN) gene variants between two different angiographic phenotypes of polypoidal choroidal vasculopathy (PCV). Methods We included 411 treatment-naïve PCV patients and 350 controls in the present study.
Honda, Shigeru   +5 more
core  

Polypoidal choroidal vasculopathy: a comprehensive clinical update

open access: yesTherapeutic Advances in Ophthalmology, 2019
Polypoidal choroidal vasculopathy as a disease is yet to be comprehended completely. The clinical features consisting of huge serosanguineous retinal pigment epithelial and neurosensory layer detachments, although unique may closely mimick neovascular ...
Atul Kumar   +8 more
doaj   +1 more source

PACHYCHOROID: an inherited condition? [PDF]

open access: yes, 2015
PURPOSE: Thick choroid (pachychoroid) is associated with central serous chorioretinopathy (CSC), but whether pachychoroid is inherited is unknown. METHODS: In a prospective observational study, first- or second-degree relatives (16 individuals) of 5 ...
Behar-Cohen, F.   +3 more
core   +1 more source

Photoreceptor layer elevation due to subretinal fluid: Impact on visual acuity measurements and simulation from biometrics

open access: yesOphthalmic and Physiological Optics, Volume 45, Issue 2, Page 480-493, March 2025.
Abstract Purpose Visual acuity (VA) is a primary outcome measure that defines the success of clinical interventions for retinal diseases such as age‐related macular degeneration (AMD) or diabetic macular oedema (DME). These conditions can lead to the presence of subretinal fluid, causing substantial photoreceptor layer elevation. Hyperopic defocus then
Vamsi Parimi   +5 more
wiley   +1 more source

Novel Retinal Imaging Technologies [PDF]

open access: yes, 2017
Newly-developed imaging techniques show extensive promise and potential to improve early detection, accurate diagnosis, and management of retinal diseases.
Li Y, Xia X, Paulus YM
core   +1 more source

Secondary Angle Closure Glaucoma due to Massive Subretinal and Suprachoroidal Hemorrhage in Neovascular Age–Related Macular Degeneration: Clinical Case and Literature Review

open access: yesCase Reports in Ophthalmological Medicine, Volume 2025, Issue 1, 2025.
Massive subretinal hemorrhage secondary to neovascular age–related macular degeneration (nAMD) is relatively uncommon, and reports of secondary angle closure glaucoma associated with such hemorrhage are even rarer. We report a case of a 93‐year‐old woman with a history of nAMD who developed this condition, along with a review of the relevant literature.
Kosuke Nagaoka   +4 more
wiley   +1 more source

Current management strategy of polypoidal choroidal vasculopathy

open access: yesIndian Journal of Ophthalmology, 2018
Polypoidal choroidal vasculopathy (PCV) is a retinal disorder commonly found in Asians presenting as neovascular age-related macular degeneration and is characterized by serous macular detachment, serous or hemorrhagic pigment epithelial detachment ...
Christine P S Ho, Timothy Y Y Lai
doaj   +1 more source

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