Revisiting Hyaluronan Catabolism in Bacteroides: Pathway Conservation, Overlooked Proteins, and Predictive Accuracy. [PDF]
MicrobiologyopenHyaluronan degradation in Bacteroides cannot be reliably predicted from canonical PL8/GH88 enzymes alone. Experimental validation reveals coordinated induction of noncanonical accessory proteins (BT4410/BT4411), highlighting pathway plasticity and context‐dependent glycosaminoglycan utilization. ABSTRACT The ability of gut microbes to degrade host‐ and
Sindelar M +6 more
europepmc +2 more sources
Biochemical, kinetic, and spectroscopic characterization of Ruegeria pomeroyi DddW - A mononuclear iron-dependent DMSP lyase [PDF]
, 2015 The osmolyte dimethylsulfoniopropionate (DMSP) is a key nutrient in marine environments and its catabolism by bacteria through enzymes known as DMSP lyases generates dimethylsulfide (DMS), a gas of importance in climate regulation, the sulfur cycle, and ...
Brummett, Adam E +4 more
core +11 more sources
Biotechnology for Biofuels, 2020 Background As the most abundant polysaccharide in brown algae, alginate has become a promising economical material for bioethanol production. Recently, exo-type alginate lyases have received extensive attention because the unsaturated monosaccharides ...
Luyao Tang +6 more
doaj +1 more source
Degradation of Alginate by a Newly Isolated Marine Bacterium Agarivorans sp. B2Z047
Marine Drugs, 2022 Alginate is the main component of brown algae, which is an important primary production in marine ecosystems and represents a huge marine biomass. The efficient utilization of alginate depends on alginate lyases to catalyze the degradation, and remains ...
Xun-Ke Sun +5 more
doaj +1 more source
Genome-Wide Analysis of PL7 Alginate Lyases in the Genus Zobellia
Molecules, 2021 We carried out a detailed investigation of PL7 alginate lyases across the Zobellia genus. The main findings were obtained using the methods of comparative genomics and spatial structure modeling, as well as a phylogenomic approach. Initially, in order to
Nadezhda Chernysheva +4 more
doaj +1 more source
Analysis of a conserved cellulase transcriptional regulator reveals inducer-independent production of cellulolytic enzymes in Neurospora crassa. [PDF]
, 2013 Cellulose is recalcitrant to deconstruction to glucose for use in fermentation strategies for biofuels and chemicals derived from lignocellulose. In Neurospora crassa, the transcriptional regulator, CLR-2, is required for cellulolytic gene expression and
Coradetti, Samuel +2 more
core +2 more sources
Bioinformatic characterisation of genes encoding cell wall degrading enzymes in the Phytophthora parasitica genome [PDF]
, 2014 BACKGROUND: A critical aspect of plant infection by the majority of pathogens is penetration of the plant cell wall. This process requires the production and secretion of a broad spectrum of pathogen enzymes that target and degrade the many complex ...
Adrienne R Hardham +2 more
core +2 more sources
Molecules, 2023 Alginate oligosaccharides (AOs) prepared through enzymatic reaction by diverse alginate lyases under relatively controllable and moderate conditions possess versatile biological activities. But widely used commercial alginate lyases are still rather rare
Hai-Ying Wang +5 more
doaj +1 more source
Characterization of a Novel Alginate Lyase from Marine Bacterium Vibrio furnissii H1
Marine Drugs, 2018 Alginate lyases show great potential for industrial and medicinal applications, especially as an attractive biocatalyst for the production of oligosaccharides with special bioactivities.
Xiaoyan Zhu +7 more
doaj +1 more source
Polysaccharide utilization loci and nutritional specialization in a dominant group of butyrate-producing human colonic Firmicutes [PDF]
, 2015 Acknowledgements The Rowett Institute of Nutrition and Health (University of Aberdeen) receives financial support from the Scottish Government Rural and Environmental Sciences and Analytical Services (RESAS).
Bernalier-Donadille, Annick +9 more
core +3 more sources