Results 91 to 100 of about 44,873 (216)

Empagliflozin does not prevent progression of Dent's disease type 1 in a mouse model

Experimental Physiology, EarlyView.
Abstract Dent's disease is a rare inherited renal disorder characterized by generalized proximal tubule dysfunction with low molecular weight proteinuria, hypercalciuria, and urinary loss of other solutes. The disease is progressive and leads to chronic kidney disease.
Elise de Combiens, Nadia Frachon, Yohan Bignon, Marc Fila, Clément Brossard, Perrine Frère, Stéphane Lourdel   +6 more
wiley   +1 more source

Heart failure is common in diabetic cats : findings from a retrospective case-controlled study in first-opinionpractice [PDF]

, 2007
Diabetes mellitus is common in the cat and the prevalence of this condition appears to be increasing (Peterson 1998,Rand and Marshall 2004, Rand and others 2004). The prognosis for cats with diabetes mellitus in first opinion practice has received little
Blue Skies Research Grant - RCVS Trust (Funder), Gettinby, G., Little, C.J.L.   +2 more
core   +1 more source

Revisiting the Incidence of Hypercalcemia in Contemporary Diagnoses of Pediatric Patients With Solid Tumors

Pediatric Blood &Cancer, Volume 72, Issue 12, December 2025.
ABSTRACT Background Hypercalcemia is rarely observed in pediatric patients with cancer. However, rare cases of renal insufficiency and osteoporosis have been reported as severe consequences. Published literature focuses predominantly on hypercalcemia in pediatric hematologic malignancies, precluding causative associations with solid tumor disease ...
Felicia Y. Ho, Dajana Alku, Chalinee Monsereenusorn, Nan Chen, Wendy B. London, Allison F. O'Neill   +5 more
wiley   +1 more source

Oxidative stress-induced NCC activation in the development of nocturnal polyuria in mice: Therapeutic potential of a sustained hydrogen-releasing silicon-based agent. [PDF]

Biochem Biophys Rep
Nocturnal polyuria is a prevalent condition associated with significant deterioration in quality of life and increased risk of mortality. Despite its clinical relevance, the underlying pathogenesis is poorly understood, and existing therapies have ...
Sekii Y, Kiuchi H, Takezawa K, Ueda N, Imanaka T, Kuribayashi S, Okada K, Fukuhara S, Imamura R, Negoro H, Kobayashi Y, Kobayashi H, Nonomura N.   +12 more
europepmc   +2 more sources

Investigating the polyuria-polydipsia syndrome: the ‘PP’ Shiny App [PDF]

, 2023
Kay Weng Choy
openalex   +1 more source

World Association for Veterinary Dermatology Consensus Statement for Diagnosis, and Evidence‐Based Clinical Practice Guidelines for Treatment and Prevention of Canine Leishmaniosis

Veterinary Dermatology, Volume 36, Issue 6, Page 723-787, December 2025.
Hyperkeratosis of (a) the footpads and (b) the nasal planum. ABSTRACT Background Canine leishmaniosis (CanL) due to Leishmania infantum remains common, and veterinarians do not always follow scientifically sound approaches for diagnosis, treatment and prevention. Objectives To provide consensus guidelines for diagnosis and evidence‐based guidelines for
Manolis N. Saridomichelakis, Gad Baneth, Silvia Colombo, Filipe Dantas‐Torres, Lluís Ferrer, Alessandra Fondati, Guadalupe Miró, Laura Ordeix, Domenico Otranto, Chiara Noli   +9 more
wiley   +1 more source

The role of zinc in renal pathological changes in diabetic status [PDF]

, 2015
Diabetes mellitus (DM) was the 8th leading cause of death in 2011, resulting in 1.4 million deaths worldwide. One of the complications of DM is chronic kidney disease, which accounts for nearly 44% of all new cases of kidney failure in the US in 2011 ...
Fernando, Julie, Zhou, Shaobo
core   +1 more source

Australian and New Zealand joint society consensus statement on genetic testing for monogenic diabetes in adults

Medical Journal of Australia, Volume 223, Issue 9, Page 484-491, November 2025.
Abstract Introduction Monogenic diabetes accounts for 2–5% of diabetes. Although its identification has substantial therapeutic implications, more than 80% of affected individuals are undiagnosed or misdiagnosed as having type 1 or 2 diabetes. This consensus statement reviews genetic testing for monogenic diabetes in adults and provides evidence‐based ...
Sunita MC De Sousa, Timothy ME Davis, James Harraway, Mark Greenslade, Kathy HC Wu, Ryan G Paul, Juliet Taylor, Aleena S Ali, Elif I Ekinci, Rinki Murphy, Jerry R Greenfield   +10 more
wiley   +1 more source

COX-2 activity transiently contributes to increased water and NaCl excretion in the polyuric phase after release of ureteral obstruction [PDF]

, 2007
  Udgivelsesdato: 2007-MayRelease of bilateral ureteral obstruction (BUO) is associated with reduced expression of renal aquaporins (AQPs), polyuria, and impairment of urine-concentrating capacity. Recently, we demonstrated that 24 h of BUO is associated
Diget, Maria, Frøkiaer, Jørgen, Jensen, Boye L, Knepper, Mark A, Nielsen, Søren, Nørregaard, Rikke, Schweer, Horst, Topcu, Sukru Oguzkan   +7 more
core   +1 more source

1H NMR Spectroscopy-Based Metabolomic Assessment of Uremic Toxicity, with Toxicological Outcomes, in Male Rats Following an Acute, Mid-Life Insult from Ochratoxin A

Toxins, 2011
Overt response to a single 6.25 mg dose of ochratoxin A (OTA) by oral gavage to 15 months male rats was progressive loss of weight during the following four days.
John P. Shockcor, Peter G. Mantle, Andrew W. Nicholls   +2 more
doaj   +1 more source