Results 91 to 100 of about 27,010 (226)
Cutaneous lesions, polyuria, polydipsia, and adenopathies in a pediatric patient [PDF]
Lucía García Sirvent
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Type 1 Diabetes and Other Autoimmune Diseases—Epidemiology, Pathophysiology and Screening
Individuals with type 1 diabetes exhibit significantly increased prevalence of additional autoimmune diseases. Epidemiological, familial and mechanistic evidence indicates frequent polyautoimmunity and shared genetic and environmental drivers. Coexistence complicates clinical management, and autoantibody‐based detection often identifies preclinical ...
George J. Kahaly +6 more
wiley +1 more source
EJE AWARD 2019: New diagnostic approaches for patients with polyuria polydipsia syndrome [PDF]
Mirjam Christ‐Crain
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The eNOS G894T polymorphism is a significant genetic risk factor for type 2 diabetes in the studied Tunisian population. The T allele appears to confer susceptibility, likely through mechanisms involving impaired eNOS function, reduced NO production and subsequent endothelial dysfunction.
Afif Ba +5 more
wiley +1 more source
Graphical Abstract ABSTRACT Objective Diabetic retinopathy (DR) is characterised by chronic neuroinflammation where the NLRP3 inflammasome plays a pivotal role. This study investigated the therapeutic potential and underlying mechanism of combining systemic metformin (MET) with intravitreal MCC950, a specific NLRP3 inhibitor, in a rodent model of DR ...
Kexuan Ren, Xiaofeng Li
wiley +1 more source
Nanoparticle‐driven nose‐to‐brain drug delivery offers a noninvasive approach to bypass the blood–brain barrier (BBB) and directly modulate reactive astrocytes in CNS disorders. This review highlights biodegradable nanoparticles for astrocyte modulation, enhancing drug bioavailability, sustained release, and neuroinflammation control.
Senamile M. Dlamini +3 more
wiley +1 more source
Noncardiogenic pulmonary oedema (suspected uraemic pneumonitis) secondary to acute kidney injury in a dog. This case suggests that noncardiogenic pulmonary oedema may have been triggered by uraemia and systemic inflammation, and that haemodialysis may have contributed to pulmonary recovery by alleviating the uraemic condition.
Se‐Hoon Kim +7 more
wiley +1 more source
The retinal pigment epithelium (RPE) plays a crucial role in retinal function, regulating the flow of metabolites and ions between the choroidal blood supply and the outer retina. Early hyperglycemia induced by streptozotocin results in elevated levels of oxidized proteins and lipid peroxidation.
Elena Morales‐Ramírez +3 more
wiley +1 more source
Rationale, design, and methods of electroencephalography-based investigation of the effects of oral desmopressin on improving slow-wave sleep time in nocturnal polyuria patients (the DISTINCT study): protocol for a single-arm, open-label, single-assignment trial [PDF]
Kazumasa Torimoto +5 more
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Objective This systematic meta‐analysis aimed to assess the effectiveness of triptorelin therapy in reducing lower urinary tract symptoms (LUTS) in men with prostate cancer (PCa).
Ravina Barrett, Brian Birch
doaj +1 more source

