Results 91 to 100 of about 26,759 (219)

Oxidative stress-induced NCC activation in the development of nocturnal polyuria in mice: Therapeutic potential of a sustained hydrogen-releasing silicon-based agent

open access: yesBiochemistry and Biophysics Reports
Nocturnal polyuria is a prevalent condition associated with significant deterioration in quality of life and increased risk of mortality. Despite its clinical relevance, the underlying pathogenesis is poorly understood, and existing therapies have ...
Yosuke Sekii   +12 more
doaj   +1 more source

Laboratory Data Analysis of Hemorrhagic Fever With Renal Syndrome Patients to Predict Disease Severity and Patient Prognosis

open access: yesJournal of Clinical Laboratory Analysis, Volume 39, Issue 23, December 2025.
Prompt access to care with proper treatment is essential for preventing patients from developing renal failure and unfavorable outcomes. This study aimed to elucidate laboratory parameters associated with HFRS severity and prognosis to predict disease course and initiate prompt clinical management.
Hong Shi   +11 more
wiley   +1 more source

Characteristics of Hearing Loss in Type 2 Diabetes Mellitus: A Systematic Review and Meta‐Analysis

open access: yesOtolaryngology–Head and Neck Surgery, Volume 173, Issue 6, Page 1317-1327, December 2025.
Abstract Methods A systematic review of CINAHL, Cochrane Library, PubMed, and SCOPUS databases was conducted according to PRISMA guidelines to identify studies evaluating T2DM and hearing loss. Primary outcome measures included continuous measures (mean), proportions (%), proportional difference (∆), and relative risks (RR) with 95% confidence ...
Cory Hyun‐su Kim   +6 more
wiley   +1 more source

Revisiting the Incidence of Hypercalcemia in Contemporary Diagnoses of Pediatric Patients With Solid Tumors

open access: yesPediatric Blood &Cancer, Volume 72, Issue 12, December 2025.
ABSTRACT Background Hypercalcemia is rarely observed in pediatric patients with cancer. However, rare cases of renal insufficiency and osteoporosis have been reported as severe consequences. Published literature focuses predominantly on hypercalcemia in pediatric hematologic malignancies, precluding causative associations with solid tumor disease ...
Felicia Y. Ho   +5 more
wiley   +1 more source

A persistent hymen resulting in an open cervix but closed pyometra and pyocolpos in a mixed‐breed female domestic dog

open access: yesVeterinary Record Case Reports, Volume 13, Issue 4, December 2025.
Abstract A rescued mixed‐breed (Africanis type), entire, female dog, approximately 2 years old, with an unknown history, presented with a prominent perineal swelling between the anus and vulva. Ultrasound identified it as a fluid‐filled structure, and an aspirate revealed an exudate consisting of degenerate neutrophils, bacterial cocci and rods.
Taylor June Kruger   +4 more
wiley   +1 more source

High‐Dose Ascorbic Acid Combined With Dihydroartemisinin Inhibits Lung Adenocarcinoma Malignancy by Inducing Ferroptosis via SLC7A11/GPX4 Pathway

open access: yesJournal of Cellular and Molecular Medicine, Volume 29, Issue 24, December 2025.
ABSTRACT This study evaluated the effect of ascorbic acid (AA) combined with dihydroartemisinin (DHA) in lung adenocarcinoma (LUAD) and the underlying mechanisms to determine whether this combination therapy provides a new therapeutic direction for the treatment of LUAD. The CCK‐8, colony formation and transwell assays were used to assess the vitality,
Lan Li   +10 more
wiley   +1 more source

Transfer of Aging: Implications for Pediatric Solid Organ Transplantation

open access: yesPediatric Transplantation, Volume 29, Issue 8, December 2025.
ABSTRACT Solid organ transplantation (SOT) is a life‐saving intervention for pediatric patients with end‐stage organ failure. Due to the limited availability of pediatric donor organs, organs from older donors are frequently utilized, increasing the risk of age‐mismatched transplants.
Rosalie Wolff von Gudenberg   +14 more
wiley   +1 more source

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