Results 51 to 60 of about 37,435 (296)

D‐Mannose Alleviates Type 2 Diabetes and Rescues Multi‐Organ Deteriorations by Controlling Release of Pathological Extracellular Vesicles

Exploration, EarlyView.
In this study, Zhang and colleagues show that drinking‐water supplementation of D‐mannose serves as an effective and potential therapeutic of type 2 diabetes, with improvement of both liver health and bone mass. The effect is exerted through suppressing macrophage release of extracellular vesicles based on metabolic control of CD36 expression.
Sha Zhang, Kai Zhang, Chen‐Xi Zheng, Ying‐Feng Gao, Guo‐Rong Deng, Xu Zhang, Yuan Yuan, Ting Jia, Si‐Yuan Tang, Guang‐Xiang He, Zhen Gong, Na Zhao, Bo Ma, Hua Tian, Hong Zhang, Zhe Li, Yong‐Chang Di‐Wu, Yi‐Han Liu, Liang Kong, Jing Ma, Yan Jin, Bing‐Dong Sui   +21 more
wiley   +1 more source

An unusual case of persistent vomiting

Journal of Medical and Scientific Research, 2017
A 40-year-old female presented with history of persistent vomitings since 6 months. History of constipation and increased frequency of urination present. History of significant weight loss is present (lost 15kgs in 6 months).
Subbarayudu, Srinivas
doaj   +1 more source

Medicine‐Food Plant Polysaccharides Modulate Diabetes and Diabetic Complications Through Maintaining Gut Function: A Review

Food Frontiers, EarlyView.
Polysaccharides derived from medicine‐food plants restore intestinal barrier integrity and microbiota balance while modulating short‐chain fatty acid levels. These modifications significantly alleviate diabetes and its complications, including nephropathy, retinopathy, cardiovascular disease, and neuropathy.
Yi Long, Wanglong Yu, Pingping Yang, Minxuan Xu, Jitao Ling, Yuting Wu, Xiao Liu, Liu Ouyang, Yan Xiong, Jianping Liu, Yiming Gan, Jing Zhang, Peng Yu, Deju Zhang   +13 more
wiley   +1 more source

Nocturnal Urine Production in Women With Global Polyuria [PDF]

International Neurourology Journal, 2020
Purpose Low nocturnal urine production (NUP) may be sufficient to rule out global polyuria (GP) in men. This study determines the sensitivity of indices for nocturnal polyuria (NP), defined as nocturnal polyuria index (NPi; nocturnal urine volume/24-hour
Thomas F. Monaghan, Adriana M. Kavoussi, Christina W. Agudelo, Syed N. Rahman, Kyle P. Michelson, Donald L. Bliwise, Jason M. Lazar, Lori A. Birder, Upeksha S. Alwis, Johan Vande Walle, Alan J. Wein, Jerry G. Blaivas, Jeffrey P. Weiss, Karel Everaert   +13 more
doaj   +1 more source

Continuous Glucose Monitoring‐Guided Self‐Management Leads to Diabetes Remission in a Newly Diagnosed Overweight Patient With Type 2 Diabetes: A Brief Report

Health Care Science, EarlyView.
ABSTRACT We report the case of a newly diagnosed overweight patient with type 2 diabetes mellitus who achieved diabetes remission using continuous glucose monitoring (CGM), which promotes patient engagement in self‐management. Key measures included selection of a patient newly diagnosed with type 2 diabetes mellitus, use of CGM, analysis of glucose ...
Xia Yang, Xiu‐Dong Liu, Yi‐Qi Guo
wiley   +1 more source

Deficiency of Carbonic Anhydrase II Results in a Urinary Concentrating Defect

Frontiers in Physiology, 2018
Carbonic anhydrase II (CAII) is expressed along the nephron where it interacts with a number of transport proteins augmenting their activity. Aquaporin-1 (AQP1) interacts with CAII to increase water flux through the water channel. Both CAII and aquaporin-
Devishree Krishnan, Devishree Krishnan, Wanling Pan, Megan R. Beggs, Megan R. Beggs, Francesco Trepiccione, Régine Chambrey, Régine Chambrey, Dominique Eladari, Dominique Eladari, Emmanuelle Cordat, Emmanuelle Cordat, Henrik Dimke, R. Todd Alexander, R. Todd Alexander, R. Todd Alexander   +15 more
doaj   +1 more source

Pyridostigmine as treatment for chronic gastrointestinal dysmotility in a child with Mowat‐Wilson syndrome: A case report and literature review

JPGN Reports, EarlyView.
Abstract Gastrointestinal dysmotility is commonly reported among patients with Mowat‐Wilson syndrome (MWS) and poses a significant symptomatic burden. Unfortunately, there remains a knowledge gap regarding effective treatment strategies. A 2‐year‐old male with MWS presented with chronic paradoxical abdominal pain, constipation, and progressively ...
Grace J. Lin, Shreya B. Kishore, Sally Samaan, Lisa S. Hackett, Kevan Jacobson, Gabriella Horvath   +5 more
wiley   +1 more source

Systemic calcinosis in a Quarter Horse gelding homozygous for a myosin heavy chain 1 mutation

Journal of Veterinary Internal Medicine, 2022
Case Description A 9‐year‐old Quarter Horse gelding was presented for lethargy, decreased appetite, polyuria and polydipsia (PU/PD), and severe muscle wasting suggestive of immune‐mediated myositis.
Beatrice T. Sponseller, David M. Wong, Rebecca Ruby, Wendy A. Ware, Scott Wilson, Joseph S. Haynes   +5 more
doaj   +1 more source

GATA1 Transcriptionally Upregulates LMCD1, Promoting Ferroptosis in Sepsis‐Associated Acute Kidney Injury Through the Hippo/YAP Pathway

The Kaohsiung Journal of Medical Sciences, EarlyView.
ABSTRACT Sepsis‐associated acute kidney injury (SA‐AKI) is associated with morbidity and mortality. Ferroptosis is associated with the pathophysiology of SA‐AKI. Here, we investigated the role of LIM and cysteine‐rich domain 1 (LMCD1) in the regulation of ferroptosis during SA‐AKI progression.
You‐Qi Zhang, Wei‐Xia Peng, You‐Fu Li, Peng Lu, Hui Liu, Wen‐Guang Liu   +5 more
wiley   +1 more source

A Case of Psychogenic Polydipsia in an Elderly: An Overlooked Diagnosis [PDF]

Journal of Clinical and Diagnostic Research
Primary polydipsia, or psychogenic polydipsia, is characterised by excessive fluid intake without an underlying physiological cause. If left untreated, primary polydipsia may result in life-threatening hyponatremia and can lead to complications such as ...
Bhumika Vaishnav, Harshitha Ummaleti, Saish Mondkar, Bhavin Sanghani, Kshitij   +4 more
doaj   +1 more source