Results 61 to 70 of about 27,010 (226)

Achilles tenocytes from diabetic and non diabetic donors exposed to hyperglycemia respond differentially to inflammatory stimuli and stretch

Journal of Anatomy, EarlyView.
Scheme depicting the experimental set up of the study. Achilles tendons and tenocytes were isolated from heterozygous (fa/+, non diabetic: non DMT2) and homozygous (fa/fa, diabetic: DMT2) Zucker Diabetic Fatty (ZDF) rats. Tendon degeneration, collagen type 1 alpha 1 chain (COL1A1) and alpha smooth muscle actin (αSMA) expression was determined in rat ...
Nils Fleischmann, Sarah Hofmann, Clemens Gögele, Eva Frank, Christian Werner, Maria Kokozidou, Bernd Hoffmann, Jens Konrad, Gundula Schulze‐Tanzil   +8 more
wiley   +1 more source

Differences in the urinary metabolome and proteome between wet and dry nights in children with monosymptomatic nocturnal enuresis and nocturnal polyuria [PDF]

, 2023
Cecilie Siggaard Jørgensen, Konstantinos Kamperis, Jane Hagelskjær Knudsen, Margrethe Kjeldsen, Jane Christensen, Luise Borch, Søren Rittig, Johan Palmfeldt   +7 more
openalex   +1 more source

Effect of a homemade diet compared to a commercial diet on glycaemic variability and glycaemic control assessed by continuous glucose monitoring system in diabetic dogs: a randomised crossover study

Journal of Small Animal Practice, EarlyView.
Objectives To evaluate the effects of a homemade diet and a commercial diet on glycaemic control and glycaemic variability of diabetic dogs monitored with the FreeStyle Libre continuous glucose monitoring system. Materials and Methods Prospective randomised crossover study including ten client‐owned diabetic dogs on insulin treatment with good ...
A. M. Tardo, C. G. Vecchiato, E. Gherlinzoni, A. Corsini, S. Corradini, F. Del Baldo, G. Biagi, F. Fracassi   +7 more
wiley   +1 more source

Electrophoretic patterns of proteinuria in dogs with Cushing’s syndrome

Journal of Small Animal Practice, EarlyView.
Objectives To describe the electrophoretic pattern of proteinuria in dogs with naturally occurring Cushing’s syndrome. We hypothesised that urine protein electrophoresis in dogs with spontaneous Cushing’s syndrome will reveal glomerular proteinuria. We also hypothesised that the severity of proteinuria would decrease during treatment with trilostane ...
J. Milenkovic, T. Francey, A. Schweighauser, J. Howard, S. Kittl, M. Campos   +5 more
wiley   +1 more source

Outcome and Toxicity Profile of Stereotactic Body Radiation Therapy for Adrenal Tumours in Dogs

Veterinary and Comparative Oncology, EarlyView.
ABSTRACT Stereotactic body radiation therapy (SBRT) has become a non‐invasive alternative option for canine adrenal tumours with high surgical risks; however, its clinical benefits and risks are still to be fully understood. The goal of this multi‐institutional retrospective study was to describe the clinical outcome and safety of SBRT for the ...
Lily Thorsen, Kimberley Law, Jillian Walz, Valerie Morales Coll, Ada Naramor, Charles Maitz, Lyndsay Kubicek, Zebulon Thorsen, Jishnu Rao Gutti, Marilia Takada   +9 more
wiley   +1 more source

Central diabetes insipidus in a young dog - case report [PDF]

Arquivo Brasileiro de Medicina Veterinária e Zootecnia
This work reports a case of an 11-month-old spayed, female mongrel with polyuria, polydipsia, polakiuria and nocturia. Serum biochemistry (alkaline phosphatase, ALT, urea, creatinine, GGT, globulins, triglycerides, cholesterol, total proteins), hemogram,
R.R. Ribeiro, T.C. Trentin, P.M.L. Camelo, I.M. Oliveira   +3 more
doaj   +1 more source

A Multi‐Institutional Retrospective Study of 21 Dogs Having Undergone Hypofractionated Radiotherapy for Adrenal Tumours (2017–2024)

Veterinary and Comparative Oncology, EarlyView.
ABSTRACT Radiation therapy (RT) has emerged as a promising non‐surgical approach for treating canine adrenal tumours. This multi‐institutional, retrospective study describes clinical outcomes for 21 dogs having been prescribed a course of hypofractionated image‐guided intensity‐modulated RT (IMRT) entailing delivery of 25–35 Gy total in 5 fractions ...
Yen‐Hao Erik Lai, Michael S. Kent, Michael W. Nolan, Dah‐Renn Fu, Jayme S. Looper   +4 more
wiley   +1 more source

Efficacy of Der f 2/Zen 1‐LAMP1 Plasmid‐Based Vaccine Immunotherapy in Dogs With Atopic Dermatitis: A Proof‐of‐Concept Study

Veterinary Dermatology, EarlyView.
Background: DNA‐based vaccination rapidly induces strong cellular and humoral immune responses, which may be enhanced by inclusion of lysosomal‐associated membrane protein‐1 (LAMP). Objectives: This proof‐of‐concept study evaluated the efficacy and safety of a Der f 2/Zen 1‐LAMP‐based DNA vaccine immunotherapy in client‐owned dogs with nonseasonal AD ...
Petra Bizikova, Chigusa Matsumoto, Shoji Ogino, Toshihiro Tsukui, Kim Love, Marcy Murphy, Ina Herrmann   +6 more
wiley   +1 more source

Oxidative stress-induced NCC activation in the development of nocturnal polyuria in mice: Therapeutic potential of a sustained hydrogen-releasing silicon-based agent

Biochemistry and Biophysics Reports
Nocturnal polyuria is a prevalent condition associated with significant deterioration in quality of life and increased risk of mortality. Despite its clinical relevance, the underlying pathogenesis is poorly understood, and existing therapies have ...
Yosuke Sekii, Hiroshi Kiuchi, Kentaro Takezawa, Norichika Ueda, Takahiro Imanaka, Sohei Kuribayashi, Koichi Okada, Shinichiro Fukuhara, Ryoichi Imamura, Hiromistu Negoro, Yuki Kobayashi, Hikaru Kobayashi, Norio Nonomura   +12 more
doaj   +1 more source

Empagliflozin does not prevent progression of Dent's disease type 1 in a mouse model

Experimental Physiology, EarlyView.
Abstract Dent's disease is a rare inherited renal disorder characterized by generalized proximal tubule dysfunction with low molecular weight proteinuria, hypercalciuria, and urinary loss of other solutes. The disease is progressive and leads to chronic kidney disease.
Elise de Combiens, Nadia Frachon, Yohan Bignon, Marc Fila, Clément Brossard, Perrine Frère, Stéphane Lourdel   +6 more
wiley   +1 more source