Repurposing a Small Molecule Plant Hormone as a Tunable ON‐Switch for CAR‐T Cell Immunotherapy
By engineering a receptor system integrating the plant auxin receptor AFB1 with its co‐receptor IAA7, we enable ligand‐dependent interactions triggered by the plant hormone auxins. This design allows rapid, reversible, and dose‐dependent T cell activation, resulting in potent cytotoxicity against B‐cell lymphoma in vitro and in vivo.
Hongxiang Zeng +16 more
wiley +1 more source
Advancements in Flexible Nanogenerators: Polyvinylidene Fluoride-Based Nanofiber Utilizing Electrospinning. [PDF]
Yoo JU +6 more
europepmc +1 more source
In human oral keratinocytes, OTUD6A promoted cell migration by deubiquitinating and stabilizing PRDX1. Conversely, OTUD6A deficiency reduced PRDX1 stability, triggering mitochondrial dysfunction and aggravating OU progression. ABSTRACT Oral ulcers (OU), as the most highly prevalent and recurrent oral mucosal lesion, have an unclear pathogenesis that ...
Xiaoyu Sun +15 more
wiley +1 more source
Percolation-Triggered Negative Permittivity in Nano Carbon Powder/Polyvinylidene Fluoride Composites. [PDF]
Shi G, Sun X, Liu Y.
europepmc +1 more source
Bio‐Based Polyurethanes for Sustainable and Multifunctional Applications
Bio‐based polyurethanes prepared from vegetable oils, lignin, and polysaccharides have attracted increasing interest as alternatives to fossil‐derived polyurethanes. This review summarizes recent progress in their chemistry, structural engineering, and advanced applications, highlighting the roles of feedstocks, chain‐segment design, dynamic covalent ...
Xin Li +6 more
wiley +1 more source
Electro-Conductive Modification of Polyvinylidene Fluoride Membrane for Electrified Wastewater Treatment: Optimization and Antifouling Performance. [PDF]
Shi J, Hu Y, Li S, Xiao W, Yang Y, Ji J.
europepmc +1 more source
Androgenetic alopecia (AGA) is a common form of hair loss with limited treatment options. Silencing of WNT5A signaling, which is widely known as the trigger of the ncWNT signaling pathway, happens in hair follicle stem cells from balding areas. It leads to downregulation of ATF3 and its target FOSB.
Ruiyu Luo +10 more
wiley +1 more source
Antibiofilm Effects of Modifying Polyvinylidene Fluoride Membranes with Polyethylenimine, Poly(acrylic acid) and Graphene Oxide. [PDF]
Castillo-Ruiz M +6 more
europepmc +1 more source
Piezo‐Coupling Effects in Smart Polymers: Toward Ultrasensitive Sensing and Biomedical Applications
Piezo‐coupling effects are the foundational factors for the development of multifunctional and self‐powered platforms. Central to this advancement is the use of stimuli‐responsive smart polymers, which offer mechanical flexibility, biocompatibility, and simplified structural complexity with improved sensitivity and energy efficiency.
Duc Khanh Tran +6 more
wiley +1 more source
Balsam-Pear-Skin-Like-Structure Polyvinylidene Fluoride/Ethylene-Vinyl Alcohol Fibrous Membrane for Highly Efficient Oil/Water Separation Through One-Step Electrospinning. [PDF]
Jiang Q +7 more
europepmc +1 more source

