Results 51 to 60 of about 1,710 (129)

Treatment of relapsed, residual and neglected clubfoot: Adjunctive surgery

Journal of Children's Orthopaedics, 2019
Over the past two decades, the Ponseti ‘conservative’ (non-surgical) method of clubfoot treatment has been almost universally adopted worldwide. As a result, the need for operative treatment for clubfoot has decreased dramatically.
M. Eidelman, P. Kotlarsky, J. E. Herzenberg   +2 more
doaj   +1 more source

CAUSES OF NON-OPTIMAL CONSERVATIVE TREATMENT OF CONGENITAL CLUBFOOT IN CHILDREN

Travmatologiâ i Ortopediâ Rossii, 2017
Introduction. Ponseti method commonly accepted as the optimal approach to management of congenital clubfoot. Continuing with alternative methods should considered as malpractice.
V. M. Kenis, Yu. A. Stepanova
doaj   +1 more source

Rapid Whole Genome Sequencing Uncovers a Triple Diagnosis: X‐Linked Chondrodysplasia Punctata, MECP2‐Related Disorder, and Mosaic Jacobs Syndrome

Molecular Genetics &Genomic Medicine, Volume 13, Issue 2, February 2025.
Neonate was found to have X‐linked chondrodysplasia punctata, MECP2‐related disorder, and mosaic Jacobs syndrome, highlighting the utility of advanced genetic testing in directing neonatal care and the complexity of managing multiple genetic diagnoses, while also adding to our understanding of the MECP2‐related disorder phenotypes in boys.
Megan Samuels, Kathleen Shields, Paul Hillman, Laura Farach   +3 more
wiley   +1 more source

Resultados del tratamiento de pie equinovaro congénito con el método de Ponseti

Revista Colombiana de Ortopedia y Traumatología, 2018
Introducción: El pie equinovaro congénito es la deformidad congénita más frecuente del pie. Actualmente, el método Ponseti es el método de referencia para el tratamiento de esta anomalía, pues provee de una corrección completa de las deformidades con ...
Pablo Rosselli Cock, Jéssica Andrea Suárez, Sebastián Rodríguez   +2 more
doaj   +1 more source

Patient with a heterozygous pathogenic variant in CSNK2A1 gene: A new case to update the Okur–Chung neurodevelopmental syndrome

American Journal of Medical Genetics Part A, Volume 194, Issue 9, September 2024.
Abstract The autosomal dominant Okur–Chung neurodevelopmental syndrome (OCNDS: OMIM #617062) is a rare neurodevelopmental disorder first described in 2016. Features include developmental delay (DD), intellectual disability (ID), behavioral problems, hypotonia, language deficits, congenital heart abnormalities, and non‐specific dysmorphic facial ...
Albin Blanc, Céline Bonnet, Marion Wandzel, Virginie Roth, Yannis Duffourd, Hanna Safraou, Bruno Leheup, Florence Muller, Julie D Colne, François Feillet, Emmanuelle Schmitt, Matheus Castro, Jullian Savatt, Adriano Burcheri, Christophe Nemos, Christophe Philippe, Laëtitia Lambert   +16 more
wiley   +1 more source

New paradigms in the study of the cholinergic system and metabolic diseases: Acetyl‐and‐butyrylcholinesterase

Journal of Cellular Physiology, Volume 239, Issue 8, August 2024.
Abstract Acetylcholinesterase (AChE) and butyrylcholinesterase (BChE) are enzymes that belong to the neuromuscular cholinergic system, their main function is to hydrolyze the neurotransmitter acetylcholine (ACh), through their hydrolysis these enzymes regulate the neuronal and neuromuscular cholinergic system.
Juan David Villeda‐González, José Luis Gómez‐Olivares, Luis Arturo Baiza‐Gutman   +2 more
wiley   +1 more source

Clubfeet and congenital constriction band syndrome

European Journal of Medical Research, 2021
Background Clubfeet and constriction band syndrome is a very rare non-idiopathic condition. Treatment is often difficult and the recurrence deformity rate is high.
Bujar Shabani, Dafina Bytyqi, Cen Bytyqi
doaj   +1 more source

Investigating the association between vitamin D dietary intake during pregnancy and incidence of clubfoot in neonates

Birth Defects Research, Volume 116, Issue 1, January 2024.
Abstract Aims Talipes equinovarus (clubfoot) is a congenital lower foot deformity that results from a neuromuscular deficiency, but the precise etiology remains elusive. Vitamin D is important for fetal neuromuscular development. In this study, we investigated the association between dietary vitamin D intake during pregnancy and incidence of clubfoot ...
Haitham T. Idriss, Martha M. Werler
wiley   +1 more source

COL1A1 regulates the apoptosis of embryonic stem cells by mediating the PITX1/TBX4 signaling

Birth Defects Research, Volume 116, Issue 1, January 2024.
Abstract Purpose The purpose of this study is to explore the regulatory function of COL1A1 against the apoptosis of embryonic stem cells (ESCs) and the potential function in congenital talipes equinovarus (CTEV). Methods Muscle tissues were collected from 20 children with CTEV and 20 children without CTEV, followed by detecting the expression of COL1A1
Xiangping Du, Xinle Wu, Lirong Yu, Wu Min, Gan Chen, Fadi Liu, Jian Li   +6 more
wiley   +1 more source

The Ponseti Method vs. Surgical Treatment for Idiopathic Clubfoot: A Prospective Long-Term Follow-Up

Children
Background: Idiopathic clubfoot is a common skeletal deformity in newborns that can cause functional limitations, pain, and reduced quality of life. The Ponseti method has become the gold standard for clubfoot treatment, replacing previous extensive ...
Martin Svehlik, Bernhard Guggenberger, Michael Stöckler, Sebastian Klim, Tanja Kraus   +4 more
doaj   +1 more source