Results 21 to 30 of about 122,799 (164)

Detection of SARS-CoV-2 through pool testing for COVID-19: an integrative review

open access: yesRevista da Sociedade Brasileira de Medicina Tropical, 2021
INTRODUCTION: The pool testing technique optimizes the number of tests performed and reduces the delivery time of results, which is an interesting strategy for the health crisis caused by the COVID-19 pandemic.
Murilo Soares Costa   +13 more
doaj   +1 more source

Synthesis and biological evaluation of Argemone mexicana-inspired antimicrobials

open access: yesBeilstein Journal of Organic Chemistry, 2023
Due to the lack of new antimicrobial drug discovery in recent years and an ever-growing prevalence of multidrug-resistant “superbugs”, there is a pressing need to explore alternative ways to combat pathogenic bacterial and fungal infections.
Jessica Villegas   +8 more
doaj   +1 more source

Interest of exome sequencing trio‐like strategy based on pooled parental DNA for diagnosis and translational research in rare diseases

open access: yesMolecular Genetics & Genomic Medicine, 2021
Background Exome sequencing (ES) has become the most powerful and cost‐effective molecular tool for deciphering rare diseases with a diagnostic yield approaching 30%–40% in solo‐ES and 50% in trio‐ES.
Frederic Tran Mau‐Them   +19 more
doaj   +1 more source

Molecular genetics of neuropsychiatric illness: some musings

open access: yesFrontiers in Genetics, 2023
Research into the genetic underpinnings of neuropsychiatric illness has occurred at many levels. As more information accumulates, it appears that many approaches may each offer their unique perspective.
Meghana Janardhanan   +3 more
doaj   +1 more source

Host selection-producing variations in the genome of hop stunt viroid

open access: yesVirus Research, 2022
A random mutant pool of hop stunt viroid (HSVd) was created by shuffling cDNA fragments prepared from three natural HSVd variants obtained from grapevine, citrus, and plum.
Teruo Sano, Akiko Kashiwagi
doaj   +1 more source

Scale Variant Vehicle Object Recognition by CNN Module of Multi-Pooling-PCA Process

open access: yesJournal of Intelligent and Connected Vehicles, 2023
The moving vehicles present different scales in the image due to the perspective effect of different viewpoint distances. The premise of advanced driver assistance system (ADAS) system for safety surveillance and safe driving is early identification of vehicle targets in front of the ego vehicle.
Yuxiang Guo, Itsuo Kumazawa, Chuyo Kaku
openaire   +2 more sources

Author Correction: Next Generation Sequencing of Pooled Samples: Guideline for Variants’ Filtering [PDF]

open access: yesScientific Reports, 2020
An amendment to this paper has been published and can be accessed via a link at the top of the paper.
Anand, Santosh   +9 more
openaire   +1 more source

Improved detection of artifactual viral minority variants in high-throughput sequencing data

open access: yesFrontiers in Microbiology, 2015
High-throughput sequencing (HTS) of viral samples provides important information on the presence of viral minority variants. However, detection and accurate quantification is limited by the capacity to distinguish biological from artificial variation. In
Matthijs Rudolf Albert Welkers   +6 more
doaj   +1 more source

Molecular classification of blood and bleeding disorder genes

open access: yesnpj Genomic Medicine, 2021
The advances and development of sequencing techniques and data analysis resulted in a pool of informative genetic data, that can be analyzed for informing decision making in designing national screening, prevention programs, and molecular diagnostic ...
Batoul Baz   +5 more
doaj   +1 more source

Design and Statistical Analysis of Pooled Next Generation Sequencing for Rare Variants [PDF]

open access: yesJournal of Probability and Statistics, 2012
Next generation sequencing (NGS) is a revolutionary technology for biomedical research. One highly cost-efficient application of NGS is to detect disease association based on pooled DNA samples. However, several key issues need to be addressed for pooled NGS.
Tao Wang   +4 more
openaire   +2 more sources

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