Results 181 to 190 of about 701,410 (306)

KLK7 overexpression promotes an aggressive phenotype and facilitates peritoneal dissemination in colorectal cancer cells

FEBS Open Bio, EarlyView.
KLK7, a tissue kallikrein‐related peptidase, is elevated in advanced colorectal cancer and associated with shorter survival. High KLK7 levels in ascites correlate with peritoneal metastasis. In mice, KLK7 overexpression increases metastasis. In vitro, KLK7 enhances cancer cell proliferation, migration, adhesion, and spheroid formation, driving ...
Yosr Z. Haffani, Tobias Dreyer, Meriem Naim, Rea Lo Dico, Natalia A. Ignatenko, Viktor Magdolen, Dalila Darmoul   +6 more
wiley   +1 more source

Automated Facial Pain Assessment Using Dual-Attention CNN with Clinically Calibrated High-Reliability and Reproducibility Framework. [PDF]

Biomimetics (Basel)
Sankoh AP, Raza A, Parwez K, Shishah W, Alharbi A, Javed M, Bilal M.   +6 more
europepmc   +1 more source

A Pooled Analysis of Gemcitabine Plus Docetaxel Versus Capecitabine Plus Docetaxel in Metastatic Breast Cancer [PDF]

, 2014
Andrew D. Seidman, Stephen Chan, Jin Wang, Chao Zhu, Cong Xu, Binghe Xu   +5 more
openalex   +1 more source

Mycobacterial cell division arrest and smooth‐to‐rough envelope transition using CRISPRi‐mediated genetic repression systems

FEBS Open Bio, EarlyView.
CRISPRI‐mediated gene silencing and phenotypic exploration in nontuberculous mycobacteria. In this Research Protocol, we describe approaches to control, monitor, and quantitatively assess CRISPRI‐mediated gene silencing in M. smegmatis and M. abscessus model organisms.
Vanessa Point, Wafaa Achache, Janïs Laudouze, Eliana Sepulveda Ramos, Mickaël Maziero, Céline Crauste, Stéphane Canaan, Pierre Santucci   +7 more
wiley   +1 more source

Assessing the potential for specimen pooling to streamline nosocomial surveillance of methicillin-resistant <i>Staphylococcus aureus</i> (MRSA). [PDF]

Microbiol Spectr
Pagotto I, Alqahtani M, Joy B, McCracken GR, Davis IR, LeBlanc JJ, Patriquin G.   +6 more
europepmc   +1 more source

dUTPase is essential in zebrafish development and possesses several single‐nucleotide variants with pronounced structural and functional consequences

FEBS Open Bio, EarlyView.
dUTPases are involved in balancing the appropriate nucleotide pools. We showed that dUTPase is essential for normal development in zebrafish. The different zebrafish genomes contain several single‐nucleotide variations (SNPs) of the dut gene. One of the dUTPase variants displayed drastically lower protein stability and catalytic efficiency as compared ...
Viktória Perey‐Simon, Angéla Békesi, Latifa Kazzazy, Jázmin Mihály, Máté Varga, Beáta G. Vértessy, Kinga Nyíri   +6 more
wiley   +1 more source

Struct2GO-Enhanced: Multimodal Graph Attention Improves Protein Function Prediction. [PDF]

J Chem Inf Model
Shi Z, Vo TH, Le NQK, Chua MCH.
europepmc   +1 more source

Differential regulation of ZFAS1 splice variants by endoplasmic reticulum stress in hepatocyte cell lines

FEBS Open Bio, EarlyView.
ZFAS1 is a lncRNA promoting cell proliferation and migration, exhibiting high expression in various cancers. It is conserved, widely expressed, and produces multiple splice variants with unclear roles. We identified several splice variants in hepatocyte models, and found that inhibiting or suppressing regulators of the unfolded protein response (PERK ...
Sébastien Soubeyrand, Paulina Lau, Ruth McPherson   +2 more
wiley   +1 more source

Brain Tumour Classification Model Based on Spatial Block-Residual Block Collaborative Architecture with Strip Pooling Feature Fusion. [PDF]

J Imaging
Tang M, Zhou X, Li Z.
europepmc   +1 more source

COMPARATIVE CHARACTERISTICS OF THE CYTOKINE POOL IN PATIENTS WITH PSORIASIS AND LICHEN PLANUS

Alla M. Bilovol, Оleksandra Havryliuk, Pustova N.O. N.O..   +2 more
openalex   +1 more source