Promiscuous stimulation of HSP70 ATPase activity by parasite‐derived J‐domains
The malaria parasite Plasmodium falciparum exports three highly homologous yet functionally divergent J‐domain proteins into human erythrocytes. Here, we show that J‐domains isolated from all three proteins effectively stimulate the ATPase activity of both endogenous host and exported parasite HSP70 chaperones.
Julian Barth +6 more
wiley +1 more source
Modifier guided resilient CNN inference enables fault-tolerant edge collaboration for IoT. [PDF]
Jamshidi O +4 more
europepmc +1 more source
Unlocking industrial-scale Quantum Annealing: A novel approach to the pooling and blending problem
Vasileios K. Mappas +4 more
openalex +1 more source
The Aging Blood: Cellular Origins, Circulating Drivers, and Therapeutic Potential
As a conduit linking all organs, the blood system both reflects and actively drives systemic aging. This review highlights how circulating pro‐aging and antiaging factors and age‐associated hematopoietic stem cell dysfunction contribute to immunosenescence and multi‐organ decline, positioning the hematopoietic system as a target for aging intervention.
Hanqing He, Jianwei Wang
wiley +1 more source
Architecture Design of a Convolutional Neural Network Accelerator for Heterogeneous Computing Based on a Fused Systolic Array. [PDF]
Zong Y, Ma Z, Ren J, Cao Y, Li M, Liu B.
europepmc +1 more source
ABSTRACT As global populations age, cancer is increasingly becoming a leading cause of morbidity and mortality among older adults, particularly in low‐ and middle‐income countries (LMICs). Despite accounting for the majority of new cancer cases and deaths, older individuals remain underrepresented in cancer research, clinical guidelines, and health ...
Ibrahim Bidemi Abdullateef +2 more
wiley +1 more source
Measured multi-source semi-supervised working condition recognition based on curvelet pooling and attention mechanism learning. [PDF]
Yang S, Zhou B, Wang Y, Liu W.
europepmc +1 more source
Visual Recovery Reflects Cortical MeCP2 Sensitivity in Rett Syndrome
ABSTRACT Objective Rett syndrome (RTT) is a devastating neurodevelopmental disorder with developmental regression affecting motor, sensory, and cognitive functions. Sensory disruptions contribute to the complex behavioral and cognitive difficulties and represent an important target for therapeutic interventions.
Alex Joseph Simon +12 more
wiley +1 more source
SleepMFormer: An Efficient Attention Framework with Contrastive Learning for Single-Channel EEG Sleep Staging. [PDF]
Li M +6 more
europepmc +1 more source
Review 1: "Personalised Risk Prediction Tools for Cryptococcal Meningitis Mortality to Guide Treatment Stratification; A Pooled Analysis of Two Randomised-controlled Trials" [PDF]
Tihana Bicanic
openalex +1 more source

