Results 151 to 160 of about 22,195 (259)

Roper romps, feeling rules, and the "appropriately inappropriate" management of joy. [PDF]

Front Sociol
Pearce JS.
europepmc   +1 more source

A Novel Pak1 Activator Ameliorates ER Stress for HFpEF Therapy

Advanced Science, EarlyView.
Chronic metabolic stress is a major contributor to HFpEF progression. Under prolonged metabolic stress, Pak1 activity becomes impaired, contributing to disrupted ER proteostasis, cardiomyocyte apoptosis, fibrosis, and diastolic dysfunction. Mechanistically, Pak1 overexpression activates the ERK1/2–MNK1–eIF4E signaling axis, promotes translational ...
Honglin Xu, Hongyuan Zhang, Tayyiba Azam, Susanne S. Hille, Yingjuan Liu, Min Zi, Jiaqing Lang, He Yu, Yujia Cao, Bernard D. Keavney, Tamer M. A. Mohamed, Jessica M. Miller, Riham R. E. Abouleisa, Ming Xu, Elizabeth J. Cartwright, Oliver J. Müller, Ming Lei, Xin Wang   +17 more
wiley   +1 more source

The precision strategy of human genome correction via a set of circular donor DNA and its cleaver. [PDF]

Front Genome Ed
Kusano K, Takizawa K, Kawaguchi J, Hara I, Mori T.   +4 more
europepmc   +1 more source

Bioadhesive‐Integrated 3D‐Printed Multilayer Scaffolds Secure a Mechanically‐Stable Osteoimmune Niche for Enhanced Bone Augmentation

Advanced Science, EarlyView.
A 3D‑printed multilayer adhesive scaffold, firmly anchored to bone defects by simple finger pressing, suppresses micromotion and secures mechanical stability of the osteogenic niche. This stabilization likely contributes to the enhanced bone augmentation by fostering a pro‑regenerative mechano‐immune profile—characterized by M2‑like macrophage ...
Delu Zhao, Qiuyi Li, Lingyun Wang, Chongao Zhang, Yutian Cheng, Shuang Liu, Fulan Wei, Zheqin Dong   +7 more
wiley   +1 more source

The Peripheral(-Muscle) Oxygenation and Perfusion Score (POP-Score): A New Non-Invasive Tool Associated with Elevations in C-Reactive Protein Levels in Neonates. [PDF]

Diagnostics (Basel)
Wolfsberger CH, Schlatzer C, Suppan E, Bruckner M, Hoeller N, Schwaberger B, Pichler G.   +6 more
europepmc   +1 more source

Multimodal Bioinspired Self‐Healing Composites Enabling Durable and High‐Efficiency Wearable Perovskite Light‐Emitting Diodes

Advanced Science, EarlyView.
Butterfly wing–inspired intrinsically self‐healing polymer interlayers enable flexible perovskite optoelectronics with high luminance, strain‐insensitive stability, and environmental resilience. These hierarchically structured films redistribute mechanical stress, suppress defect formation, and maintain performance under repeated bending, paving the ...
Loganathan Veeramuthu, Yu‐Chen Wang, Chun‐Tse Tsai, Yen‐Lin Tseng, Xuan Ting King, Tzu‐Ming Hsu, Zhen‐Li Yan, Fang‐Cheng Liang, Pei‐Yin Chen, Georgy Dosovitskiy, Yehonadav Bekenstein, Hyunjin Lee, Tao Zhou, Chi‐Ching Kuo   +13 more
wiley   +1 more source

The Politics of Pop-culture – Introduction

Praktyka Teoretyczna, 2014
Tomasz Żaglewski,, Piotr Juskowiak
doaj   +1 more source

Are societies becoming more self-centric? Evidence from five decades of popular music spanning three continents. [PDF]

PLoS One
Golubickis M, Jalalian P, Masroujah LS, Selvaraj ES, Sharma Y, Seow SH, Borrego-Guerrero A, Marr S, Macrae CN.   +8 more
europepmc   +1 more source

Polystyrene Nanoplastics Drive β‐Cell Dedifferentiation Through Dendritic Cell‐Intrinsic MHC‐I‐Dependent Inflammatory Crosstalk

Advanced Science, EarlyView.
Polystyrene nanoplastics disrupt pancreatic immune–endocrine homeostasis by promoting MHC‐I‐associated dendritic cell activation and inflammatory crosstalk with β cells. This immune remodeling drives β‐cell dedifferentiation, impairs insulin secretion, and aggravates metabolic dysfunction, revealing a previously unrecognized immunometabolic mechanism ...
Conghui Qiao, Yuqing Song, Fang Yang, Menghui Guo, Libin Jiang, Xiaoyue Quan, Wei Wei, Xinyang Wang, Tianshu Han, Mingyuan Liu, Wenbo Jiang   +10 more
wiley   +1 more source

Impact of a large-scale interactive and immersive science pop-up shop about infection and hygiene on visitors and volunteers. [PDF]

Front Public Health
Tyrrell JM, Abdulgafar A, Sadeghzadeh Rahimi P, Sparling GB, Cox FKA, Maros LB, Lewis J, Stanton N, Hatch S, Smith C, Cuff SM, Aicheler RJ, Eberl M.   +12 more
europepmc   +1 more source