Results 31 to 40 of about 487,860 (287)
Cryptochrome and PAS/LOV proteins play intricate roles in circadian clocks where they act as both sensors and mediators of protein–protein interactions. Their ubiquitous presence in signaling networks has positioned them as targets for small‐molecule therapeutics. This review provides a structural introduction to these protein families.
Eric D. Brinckman +2 more
wiley +1 more source
Effects of Pop Culture for Improving Student- Teachers' Writing Skill (a Case Study at Galuh University) [PDF]
Writing, one of the four skills which have to be taught by educators in language learning. Starting from classroom observation implied that students confronted the difficulties in writing involving generating ideas, organizing words, and making ...
Ratnawati, R. (Ratnawati)
core
Aggressive prostate cancer is associated with pericyte dysfunction
Tumor‐produced TGF‐β drives pericyte dysfunction in prostate cancer. This dysfunction is characterized by downregulation of some canonical pericyte markers (i.e., DES, CSPG4, and ACTA2) while maintaining the expression of others (i.e., PDGFRB, NOTCH3, and RGS5).
Anabel Martinez‐Romero +11 more
wiley +1 more source
Intein‐based modular chimeric antigen receptor platform for specific CD19/CD20 co‐targeting
CARtein is a modular CAR platform that uses split inteins to splice antigen‐recognition modules onto a universal signaling backbone, enabling precise, scarless assembly without re‐engineering signaling domains. Deployed here against CD19 and CD20 in B‐cell malignancies, the design supports flexible multi‐antigen targeting to boost T‐cell activation and
Pablo Gonzalez‐Garcia +9 more
wiley +1 more source
The Role of Interior Design Elements in Attracting K-pop Lovers at Mujigae Restaurants in Bandung [PDF]
The existence of Korean culture has become increasingly well-known by Indonesian people, it has become a venue for restaurant entrepreneurs to compete hard to win the hearts of consumers.
Hadiansyah, M. N. (Mahendra ) +2 more
core
Potential therapeutic targeting of BKCa channels in glioblastoma treatment
This review summarizes current insights into the role of BKCa and mitoBKCa channels in glioblastoma biology, their potential classification as oncochannels, and the emerging pharmacological strategies targeting these channels, emphasizing the translational challenges in developing BKCa‐directed therapies for glioblastoma treatment.
Kamila Maliszewska‐Olejniczak +4 more
wiley +1 more source
No shame to play: Ludic prosumption on Brazilian fanvideos [PDF]
Purpose – Fans are proactive consumers of pop culture products, who can be seen as prosumers. Fanvideo production is one of their most widespread practices in the participatory culture scenario.
André Luiz Maranhão de Souza-Leão +4 more
doaj +1 more source
Songs of the Factory: Pop Music, Culture, and Resistance [PDF]
Having made the case for an ethnographic study of how workers hear and use music, I now turn to connect the topic to bigger questions within industrial sociology, musicology, and cultural studies—questions regarding the nature of popular music in ...
Korczynski, Marek
core +1 more source
Come to Daddy? Claiming Chris Cunningham for British Art Cinema [PDF]
Twenty years after he came to prominence via a series of provocative, ground-breaking music videos, Chris Cunningham remains a troubling, elusive figure within British visual culture.
Adams R. +23 more
core +1 more source
Plecstatin inhibits hepatocellular carcinoma tumorigenesis and invasion through cytolinker plectin
The ruthenium‐based metallodrug plecstatin exerts its anticancer effect in hepatocellular carcinoma (HCC) primarily through selective targeting of plectin. By disrupting plectin‐mediated cytoskeletal organization, plecstatin inhibits anchorage‐dependent growth, cell polarization, and tumor cell dissemination.
Zuzana Outla +10 more
wiley +1 more source

