Results 31 to 40 of about 8,026,083 (260)

Reflection of Helping and Cooperation in the Popular Literature of South Khorasan [PDF]

open access: yesDānishhā-yi būmī-i Īrān
The popular literature of any land is a suitable platform for reflecting its social and cultural issues, which are presented in the form of proverbs, allegories, songs, etc.
tahere mirzaei, mohammad ali talebi
doaj   +1 more source

SOCIAL DRAMATURGY ROLES PERFORMANCE IN BATMAN THE DARK KNIGHT RISES 2012 BY CHRISTOPHER NOLAN

open access: yesSaksama, 2022
This study aims to analyze the social dramaturgy aspect in the film "The Dark Knight Rises" using the qualitative descriptive method. The study is guided by the sociological perspective of Erving Goffman, who proposed the concept of front and backstage ...
Asyraf Sulaeman, Sape'i Sape'i
doaj   +1 more source

Smaller is better: nanobodies meet NMR

open access: yesFEBS Letters, EarlyView.
Nanobodies are single‐domain antigen‐binding fragments derived from camelid heavy chain antibodies. Their small size, high stability, and exceptional specificity make nanobodies uniquely useful probes for NMR studies of protein dynamics, transient conformational states, and protein–protein interactions.
Oleg Y. Dmitriev
wiley   +1 more source

Contemporary Australian Literature [PDF]

open access: yes, 2015
Australia has been seen as a land of both punishment and refuge. Australian literature has explored these controlling alternatives, and vividly rendered the landscape on which they transpire. Twentieth-century writers left Australia to see the world; now
Birns, Nicholas
core   +1 more source

Hijacking emergency granulopoiesis: Neutrophil ontogeny and reprogramming in cancer

open access: yesMolecular Oncology, EarlyView.
Neutrophils are highly plastic innate immune cells; their functions in cancer extend beyond the tumour microenvironment. This Review summarises current understanding of neutrophil maturation and heterogeneity and highlights tumour‐induced granulopoiesis as a systemic programme that expands immature, immunosuppressive neutrophils via tumour‐derived ...
Gabriela Marinescu, Yi Feng
wiley   +1 more source

Spatial and single‐nuclei transcriptomics reveals idiosyncratic and generic patterns in papillary and anaplastic thyroid cancers

open access: yesMolecular Oncology, EarlyView.
Matched spatial transcriptomics and single‐nuclei RNA‐seq were generated for anaplastic and BRAFV600E papillary thyroid cancers revealing generic and tumor‐specific states occurring in cancer cells and in the tumor microenvironment. In this context, cancer dedifferentiation mirrored organoid maturation through ordered thyroid marker gain/loss ...
Adrien Tourneur   +11 more
wiley   +1 more source

Targeting transcription factors associated with hemoglobinopathies: Lessons from successful interventions and implications for cancer

open access: yesMolecular Oncology, EarlyView.
This review summarizes the transcription factors, repressive chromatin‐modifying complexes, and epigenetic mechanisms that control fetal hemoglobin repression. Notably, many regulators of γ‐globin silencing also function in transcriptional and epigenetic networks that drive cancer, highlighting opportunities to translate advances in hemoglobinopathy ...
Meigen Yu   +3 more
wiley   +1 more source

High or popular literature?: John Updike's Rabbit series

open access: yesActa Neophilologica, 2010
The article addresses the issue of the ambivalent relationship between high and popular literature. Relying on the criteria proposed by Ken Gelder, the author seeks to prove those artistic qualities of John Updike's Rabbit sequence that ensure his ...
Jerneja Petrič
doaj   +1 more source

Unraveling 4‐Phenylbutyrate's Therapeutic Role in SLC6A1 Disorders: Pharmacochaperoning Over HDAC Inhibition

open access: yesAnnals of Clinical and Translational Neurology, EarlyView.
ABSTRACT Objective Variants in SLC6A1, encoding the GABA transporter 1 (GAT‐1), cause epilepsy, autism spectrum disorder, and developmental delay via loss of GABA uptake, impaired trafficking, and ER retention. We previously found that 4‐Phenylbutyrate (PBA), an FDA‐approved drug, restores GABA uptake and reduces seizures in SLC6A1‐related disorders ...
Melissa B. DeLeeuw   +5 more
wiley   +1 more source

Underhållning på rätt sätt

open access: yesBarnboken: Tidskrift för Barnlitteraturforskning
Theme: The Children’s Library Saga and the Swedish Teachers’ Magazine’s Publishing House. Logo: The Swedish Institute for Children's Books Entertainment the Right Way: The Book Series Stjärnböckerna and Svensk läraretidnings förlag as Literary ...
Sara Kärrholm
doaj   +1 more source

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