Data‐Independent Acquisition Mass Spectrometry in Tumor Classification and Cancer Biomarker Research
Abstract Cancer treatment is far from optimal also because current classification systems do not reflect the complex molecular status of the tumor and its phenotype in sufficient detail. To construct molecular tumor classifiers, omics tools provide complex molecular data reflecting many aspects from genotype to phenotype.
Jan Simonik +3 more
wiley +1 more source
Ion Activation Methods for Top‐Down Proteomics
ABSTRACT Mass spectrometry (MS) has emerged as a premier method used to characterize the sequences of proteins. Top‐down proteomics aims to capture the multiple sources of structural diversity reflected in proteins, such as those that arise from alternative RNA splicing events or the addition of post‐translational modifications. Tandem MS (i.e., MS/MS)
Jada N. Walker, Jennifer S. Brodbelt
wiley +1 more source
ABSTRACT Top‐down proteomics (TDP) characterizes proteoforms in cells, tissues, and biofluids, in discovery mode and on a global scale, requiring analytical tools with high peak capacity for proteoform separation and high sensitivity for proteoform detection, given the extremely high proteoform complexity and wide proteoform concentration dynamic range.
Guijie Zhu +5 more
wiley +1 more source
Four constitutive models are evaluated for FeCoNiCr and Al0.6FeCoNiCr HEAs under wide temperature and strain‐rate conditions. The predictive capabilities and limitations of each model are then critically assessed, with particular emphasis on strain rate sensitivity, temperature dependence, and physically unrealistic responses at extreme loading ...
Yooseob Song +3 more
wiley +1 more source
Treatment differentiation between group music therapy and recreational choir singing for people with dementia and depression living in residential care homes: structured video analysis of the interventions in the MIDDEL trial. [PDF]
Bloska J +8 more
europepmc +1 more source
Conditional Generative Modeling for Enhanced Credit Risk Management in Supply Chain Finance
ABSTRACT The rapid expansion of cross‐border e‐commerce (CBEC) has created significant opportunities for small‐ and medium‐sized sellers, yet financing remains a critical challenge due to their limited credit histories. Third‐party logistics (3PL)‐led supply chain finance (SCF) has emerged as a promising solution, leveraging in‐transit inventory as ...
Qingkai Zhang, L. Jeff Hong, Houmin Yan
wiley +1 more source
Use of headphones for the delivery of music programs for people with dementia in long-term care homes: a scoping review. [PDF]
Huang Y +6 more
europepmc +1 more source
Abstract The expansion of grey wolves (Canis lupus) across the western United States, including on public lands used for extensive livestock grazing, requires tools and techniques for reducing wolf–livestock conflict and supporting coexistence. We examined approaches used on forested lands managed by the U.S.
Robert M. Anderson +3 more
wiley +1 more source
Assessing the Role of Vocal Plasticity in Sociospatial Coordination. [PDF]
Mercado E, Hyland Bruno J.
europepmc +1 more source
A dramaturgy of uncertainty: Transdisciplinary manoeuvres across forestry and theatre
Abstract The uncertainties of climate change mean that forestry adaptation strategies are often complex and contested. Research has suggested that there is an interest in the forestry sector for facilitated dialogue about uncertainty (de Pellegrin Llorente et al., 2023).
Rachel Clive +4 more
wiley +1 more source

