Results 161 to 170 of about 394,943 (305)

Data‐Independent Acquisition Mass Spectrometry in Tumor Classification and Cancer Biomarker Research

open access: yesMass Spectrometry Reviews, EarlyView.
Abstract Cancer treatment is far from optimal also because current classification systems do not reflect the complex molecular status of the tumor and its phenotype in sufficient detail. To construct molecular tumor classifiers, omics tools provide complex molecular data reflecting many aspects from genotype to phenotype.
Jan Simonik   +3 more
wiley   +1 more source

Ion Activation Methods for Top‐Down Proteomics

open access: yesMass Spectrometry Reviews, EarlyView.
ABSTRACT Mass spectrometry (MS) has emerged as a premier method used to characterize the sequences of proteins. Top‐down proteomics aims to capture the multiple sources of structural diversity reflected in proteins, such as those that arise from alternative RNA splicing events or the addition of post‐translational modifications. Tandem MS (i.e., MS/MS)
Jada N. Walker, Jennifer S. Brodbelt
wiley   +1 more source

Recent Advances (2023–2025) of Capillary Electrophoresis‐Mass Spectrometry (CE‐MS) for Top‐Down Proteomics

open access: yesMass Spectrometry Reviews, EarlyView.
ABSTRACT Top‐down proteomics (TDP) characterizes proteoforms in cells, tissues, and biofluids, in discovery mode and on a global scale, requiring analytical tools with high peak capacity for proteoform separation and high sensitivity for proteoform detection, given the extremely high proteoform complexity and wide proteoform concentration dynamic range.
Guijie Zhu   +5 more
wiley   +1 more source

A Comparison of Classical Constitutive Models for High‐Entropy Alloy Behavior: Effects of Medium Strain Rates and Temperature on Plastic Flow

open access: yesMaterials Genome Engineering Advances, EarlyView.
Four constitutive models are evaluated for FeCoNiCr and Al0.6FeCoNiCr HEAs under wide temperature and strain‐rate conditions. The predictive capabilities and limitations of each model are then critically assessed, with particular emphasis on strain rate sensitivity, temperature dependence, and physically unrealistic responses at extreme loading ...
Yooseob Song   +3 more
wiley   +1 more source

Conditional Generative Modeling for Enhanced Credit Risk Management in Supply Chain Finance

open access: yesNaval Research Logistics (NRL), EarlyView.
ABSTRACT The rapid expansion of cross‐border e‐commerce (CBEC) has created significant opportunities for small‐ and medium‐sized sellers, yet financing remains a critical challenge due to their limited credit histories. Third‐party logistics (3PL)‐led supply chain finance (SCF) has emerged as a promising solution, leveraging in‐transit inventory as ...
Qingkai Zhang, L. Jeff Hong, Houmin Yan
wiley   +1 more source

Large, rugged and remote: The challenge of wolf–livestock coexistence on federal lands in the American West

open access: yesPeople and Nature, EarlyView.
Abstract The expansion of grey wolves (Canis lupus) across the western United States, including on public lands used for extensive livestock grazing, requires tools and techniques for reducing wolf–livestock conflict and supporting coexistence. We examined approaches used on forested lands managed by the U.S.
Robert M. Anderson   +3 more
wiley   +1 more source

A dramaturgy of uncertainty: Transdisciplinary manoeuvres across forestry and theatre

open access: yesPeople and Nature, EarlyView.
Abstract The uncertainties of climate change mean that forestry adaptation strategies are often complex and contested. Research has suggested that there is an interest in the forestry sector for facilitated dialogue about uncertainty (de Pellegrin Llorente et al., 2023).
Rachel Clive   +4 more
wiley   +1 more source

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