Our study reveals a novel mechanism of a positive regulatory circuit between Cav1.2 and H3K27ac for pancreatic neuroendocrine neoplasms (pNENs) progression. Cav1.2 is identified as a crucial target for promoting disease progression and correlates with malignant behaviors, which are remarkably inhibited by the administration of calcium channel blockers (
Yangyinhui Yu +12 more
wiley +1 more source
Quo vadis? Evolving trends in fine-needle aspiration cytology practice: A personal perspective. [PDF]
Paksoy N.
europepmc +1 more source
Fair Load Balancing under Skewed Popularity Patterns in Heterogeneous DHT-Based P2P Systems
Maha Abdallah, Eliya Buyukkaya
openalex +1 more source
Analyzing X's Web of Influence: Dissecting News Sharing Dynamics through Credibility and Popularity with Transfer Entropy and Multiplex Network Measures [PDF]
Sina Abdidizaji +5 more
openalex +1 more source
All‐PEG‐Like Block Copolymers Self‐Assemble into Stealth Nanocarriers for Drug Delivery
Self‐assembling nanoparticles composed entirely of POEGMA are engineered by exploiting side‐chain–dependent amphiphilicity and tunable thermoresponsive behavior. These single‐material nanocarriers encapsulate diverse hydrophobic drugs with high efficiency, retain therapeutic activity, improve in vivo efficacy, and evade anti‐PEG antibodies.
Parul Sirohi +15 more
wiley +1 more source
An Evaluation of the Popularity of Australian Native Bee Taxa and State of Knowledge of Native Bee Taxonomy Among the Bee-Interested Public. [PDF]
Prendergast K.
europepmc +1 more source
Complexity of popularity and dynamics of within-game achievements in computer games [PDF]
Leonardo R. Cunha +2 more
openalex +1 more source
Linearizing and Forecasting: A Reservoir Computing Route to Digital Twins of the Brain
A new approach uses simple neural networks to create digital twins of brain activity, capturing how different patterns unfold over time. The method generates and recovers key dynamics even from noisy data. When applied to fMRI, it predicts brain signals and reveals distinctive activity patterns across regions and individuals, opening possibilities for ...
Gabriele Di Antonio +3 more
wiley +1 more source
Mapping the political landscape from data traces: Multidimensional opinions of users, politicians and media outlets on X. [PDF]
Vendeville A +11 more
europepmc +1 more source

