Results 91 to 100 of about 368,691 (302)

Reduced vascular leakage correlates with breast carcinoma T regulatory cell infiltration but not with metastatic propensity

open access: yesMolecular Oncology, EarlyView.
A mouse model for vascular normalization and a human breast cancer cohort were studied to understand the relationship between vascular leakage and tumor immune suppression. For this, endothelial and immune cell RNAseq, staining for vascular function, and immune cell profiling were employed.
Liqun He   +8 more
wiley   +1 more source

The Gamma Ray Pulsar Population [PDF]

open access: yes, 1999
We apply a likelihood analysis to pulsar detections, pulsar upper limits, and diffuse background measurements from the OSSE and EGRET instruments on the Compton Gamma Ray Observatory to constrain the luminosity law for gamma-ray pulsars and some ...
Becker W.   +6 more
core   +2 more sources

Cancers in Australia in 2010 attributable to overweight and obesity

open access: yesAustralian and New Zealand Journal of Public Health, 2015
Objectives: To estimate the proportion and number of cancers occurring in Australia in 2010 attributable to overweight/obesity. Methods: We estimated the population attributable fraction (PAF) and number of cancers causally associated with overweight ...
Bradley J. Kendall   +6 more
doaj   +1 more source

Basic parametric analysis for a multi-state model in hospital epidemiology

open access: yesBMC Medical Research Methodology, 2017
Background The extended illness-death model is a useful tool to study the risks and consequences of hospital-acquired infections (HAIs). The statistical quantities of interest are the transition-specific hazard rates and the transition probabilities as ...
Maja von Cube   +2 more
doaj   +1 more source

In vitro models of cancer‐associated fibroblast heterogeneity uncover subtype‐specific effects of CRISPR perturbations

open access: yesMolecular Oncology, EarlyView.
Development of therapies targeting cancer‐associated fibroblasts (CAFs) necessitates preclinical model systems that faithfully represent CAF–tumor biology. We established an in vitro coculture system of patient‐derived pancreatic CAFs and tumor cell lines and demonstrated its recapitulation of primary CAF–tumor biology with single‐cell transcriptomics ...
Elysia Saputra   +10 more
wiley   +1 more source

Cancers in Australia in 2010 attributable to insufficient physical activity

open access: yesAustralian and New Zealand Journal of Public Health, 2015
Objectives: To estimate the proportion and numbers of cancers occurring in Australia in 2010 attributable to insufficient levels of physical activity. Methods: We estimated the population attributable fraction (PAF) of cancers causally associated with ...
Catherine M. Olsen   +7 more
doaj   +1 more source

Association of Hypertension According to New American College of Cardiology/American Heart Association Blood Pressure Guidelines With Incident Dementia in the ARIC Study Cohort

open access: yesJournal of the American Heart Association: Cardiovascular and Cerebrovascular Disease, 2020
Background The impact of the new 2017 American College of Cardiology/American Heart Association (ACC/AHA) hypertension guideline on dementia risk at the population level has not been evaluated. Methods and Results We studied dementia‐free participants in
Jeffrey D. Hodis   +6 more
doaj   +1 more source

Developing evidence‐based, cost‐effective P4 cancer medicine for driving innovation in prevention, therapeutics, patient care and reducing healthcare inequalities

open access: yesMolecular Oncology, EarlyView.
The cancer problem is increasing globally with projections up to the year 2050 showing unfavourable outcomes in terms of incidence and cancer‐related deaths. The main challenges are prevention, improved therapeutics resulting in increased cure rates and enhanced health‐related quality of life.
Ulrik Ringborg   +43 more
wiley   +1 more source

Cancers in Australia in 2010 attributable to inadequate consumption of fruit, non‐starchy vegetables and dietary fibre

open access: yesAustralian and New Zealand Journal of Public Health, 2015
Objectives: To estimate the number and proportion of cancers occurring in Australia in 2010 attributable to consumption deficits in fruit, non‐starchy vegetables and dietary fibre.
Christina M. Nagle   +7 more
doaj   +1 more source

Preventable cancer cases and deaths attributable to deficit of physical activity in Korea from 2015 to 2030 [PDF]

open access: yesEpidemiology and Health
OBJECTIVES This study aimed to determine the population-attributable fractions (PAFs) of cancers using various calculation methods and to estimate the PAFs of cancer incidence and mortality resulting from deficit in physical activity (DPA) from 2015 to ...
Soseul Sung   +27 more
doaj   +1 more source

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