Results 81 to 90 of about 368,691 (302)

Population attributable fraction of infection-related cancers in Korea

Annals of Oncology, 2011
A number of infectious agents have been classified as human carcinogens. The purpose of the current study was to provide an evidence-based assessment of the burden of infection-related cancers in the Korean population.The population attributable fraction was calculated using infection prevalence data from 1990 or earlier, relative risk estimates from ...
Shin, A., Park, S., Shin, H. R., Park, E. -H., Park, S. K., Oh, J. -K., Lim, M. -K., Choi, B. Y., Boniol, M., Boffetta, P.   +9 more
openaire   +3 more sources

Characterizing Parental Concerns About Lasting Impacts of Treatment in Children With B‐Acute Lymphoblastic Leukemia

Pediatric Blood &Cancer, EarlyView.
ABSTRACT Background B‐acute lymphoblastic leukemia (B‐ALL) is the most common pediatric cancer, and while most children in high‐resource settings are cured, therapy carries risks for long‐term toxicities. Understanding parents’ concerns about these late effects is essential to guide anticipatory support and inform evolving therapeutic approaches ...
Kellee N. Parker, Sarah W. Alexander, Lisa M. Jacola, Kimberly A. Buff, Kyobin Hwang, Elham Hashemi, Gregory Stoddard, Lindsay A. Jibb   +7 more
wiley   +1 more source

Attributable Risk Function in the Proportional Hazards Model [PDF]

, 2005
As an epidemiological parameter, the population attributable fraction is an important measure to quantify the public health attributable risk of an exposure to morbidity and mortality.
Chen, Ying Qing, Hu, Chengcheng, Wang, Yan   +2 more
core   +1 more source

Senescence in vitro and ionising radiations—the human diploid fibroblast model [PDF]

, 1981
The influence of ionising radiations on ageing is still controversial. Since Hayflick established the concept that diploid cells have finite lifespan in vitro, human diploid fibroblast (HDF) cultures have been recognised as a potent experimental model ...
A.F.G. Stevenson, Ban, Beer, Carrel, Cox, Cremer, Cristofalo, Ebeling, Finch, Fukushima, Guichard, Hayflick, Hayflick, Hayflick, Hoehn, Holliday, Holliday, Hopwood, Hug, Kaji, Kirkwood, Kirkwood, Laublin, Lima, Macieira-Coelho, Macieira-Coelho, Macieira-Coelho, Macieira-Coelho, Macieira-Coelho, Maisin, Martin, Namba, Nicholas, Orgel, Orgel, Russ, Schneider, Schneider, Smith, Stevenson, T. Cremer, Walburg, Weismann, Williams, Wilson   +44 more
core   +1 more source

Population Attributable Fraction of Helicobacter pylori Infection–Related Gastric Cancer in Korea: A Meta-Analysis

Cancer research and treatment : official journal of Korean Cancer Association, 2020
Purpose This study aimed to determine the proportion of gastric cancer attributable to Helicobactor pylori in the Korean population. Infection with H. pylori has been recognized as the most significant risk factor for gastric cancer.
Yoon Park, M. Ki
semanticscholar   +1 more source

By dawn or dusk—how circadian timing rewrites bacterial infection outcomes

FEBS Letters, EarlyView.
The circadian clock shapes immune function, yet its influence on infection outcomes is only beginning to be understood. This review highlights how circadian timing alters host responses to the bacterial pathogens Salmonella enterica, Listeria monocytogenes, and Streptococcus pneumoniae revealing that the effectiveness of immune defense depends not only
Devons Mo, Catherine S. Palmer, Jacqueline M. Kimmey   +2 more
wiley   +1 more source

Crosstalk between the ribosome quality control‐associated E3 ubiquitin ligases LTN1 and RNF10

FEBS Letters, EarlyView.
Loss of the E3 ligase LTN1, the ubiquitin‐like modifier UFM1, or the deubiquitinating enzyme UFSP2 disrupts endoplasmic reticulum–ribosome quality control (ER‐RQC), a pathway that removes stalled ribosomes and faulty proteins. This disruption may trigger a compensatory response to ER‐RQC defects, including increased expression of the E3 ligase RNF10 ...
Yuxi Huang, Satoshi Hashimoto, Sota Ito, Chisato Kikuguchi, Miho Hoshi, Kiyoshi Yamaguchi, Yoichi Furukawa, Toru Suzuki, Toshifumi Inada   +8 more
wiley   +1 more source

Diabetes and tuberculosis: the impact of the diabetes epidemic on tuberculosis incidence. [PDF]

, 2007
BACKGROUND: Tuberculosis (TB) remains a major cause of mortality in developing countries, and in these countries diabetes prevalence is increasing rapidly. Diabetes increases the risk of TB.
Dye, Chirstopher, Forouhi, Nita G., Lauer, Jeremy A., Roglic, Gojka, Stevenson, Catherine R., Unwin, Nigel, Williams, Brian G.   +6 more
core   +2 more sources

Risk and population attributable fraction of metabolic syndrome and impaired fasting glucose for the incidence of type 2 diabetes mellitus among middle‐aged Japanese individuals: Aichi Worker’s Cohort Study

Journal of Diabetes Investigation, 2020
The Japanese government started a nationwide screening program for metabolic syndrome (MetS) to prevent cardiovascular diseases and diabetes in 2008. Although impaired fasting glucose (IFG) is a strong predictor for type 2 diabetes mellitus, the program ...
Kayo Kaneko, H. Yatsuya, Yuanying Li, M. Uemura, Chifa Chiang, Y. Hirakawa, A. Ota, K. Tamakoshi, A. Aoyama   +8 more
semanticscholar   +1 more source

β‐TrCP overexpression enhances cisplatin sensitivity by depleting BRCA1

Molecular Oncology, EarlyView.
Low levels of β‐TrCP (Panel A) allow the accumulation of BRCA1 and CtIP, which facilitate the repair of cisplatin‐induced DNA damage via homologous recombination (HR) and promote tumor cell survival. In contrast, high β‐TrCP expression (Panel B) leads to BRCA1 and CtIP degradation, impairing HR repair, resulting in persistent DNA damage and apoptosis ...
Rocío Jiménez‐Guerrero, Alejandro Belmonte‐Fernández, Mónica González‐Moreno, Laura Rodríguez‐Cordero, Begoña Pérez‐Valderrama, Joaquín Herrero‐Ruíz, Francisco Romero, Carmen Sáez, Miguel Á. Japón   +8 more
wiley   +1 more source