Results 151 to 160 of about 58,959,543 (293)

Health Care Utilization in Adults With Congenital Heart Disease: Population-Based Findings. [PDF]

Birth Defects Res
Crume TL, Khanna AD, Tillman A, Lui GK, Soim AS, Hsu DT, Sommerhalter K, Sullivan A, Li JS, D Ottavio A, Book WM, Raskind-Hood C, Whitehead K, Pinto N, Feldkamp ML, Reeder MR, Krikov S, Botto LD.   +17 more
europepmc   +1 more source

Interpreting the effects of DNA polymerase variants at the structural level

Molecular Oncology, EarlyView.
Using MAVISp and molecular dynamics simulations, we analyzed over 60 000 missense variants in POLE and POLD1 from ClinVar, COSMIC, cBioPortal, and saturation mutagenesis. Identified mechanistic indicators, including stability, binding, and long‐range, enable structural interpretation, providing ACMG‐like evidence for possible reclassification of VUS ...
Matteo Arnaudi, Karolina Krzesińska, Ludovica Beltrame, Pablo Sánchez‐Izquierdo Besora, Matteo Tiberti, Mef Nilbert, Anna Rohlin, Elena Papaleo   +7 more
wiley   +1 more source

Carbon Footprint of Childhood Diets-A Secondary Analysis of Population-Based Studies. [PDF]

Curr Dev Nutr
Odinsdottir T, Gudmannsdottir R, Novotny R, Thorisdottir B, Thorsdottir I.   +4 more
europepmc   +1 more source

Population headliners. No.299, March-April 2004

, 2004
The newsletter is produced with support from the United Nations Population Fund (UNFPA), Project No. RAS5P203 ESCAP's project on population approved ... 2 2004 United Nations Population Award ... 3 ESCAP releases 2004 Population Data Sheet ...
United Nations Population Fund (UNFPA), UN.ESCAP   +1 more
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Proteasome inhibitor, ixazomib prevents topoisomerase‐I degradation and reverses irinotecan resistance in colorectal cancer

Molecular Oncology, EarlyView.
Ixazomib inhibits proteasome‐mediated degradation of topoisomerase I induced by irinotecan, thereby restoring drug sensitivity and promoting tumor cell death in colorectal cancer. Irinotecan, a topoisomerase I (topoI) inhibitor, is widely used for colorectal cancer, but resistance remains a major clinical challenge.
Yuho Ebata, Koji Ando, Hirofumi Hasuda, Koshi Mimori, Elizabeth C. Unan, Siddhartha Pulukuri, Aahana Tiku, Allison Berger, Eiji Oki, Ajit Bharti, Tomoharu Yoshizumi   +10 more
wiley   +1 more source

Incidence of anxiety disorders following Parkinson's disease: a population-based cohort study. [PDF]

Front Psychiatry
Bae Y, Han J, Jeon SR, Shin W, Dong JJ, Jung H, Lee SW.   +6 more
europepmc   +1 more source

What do Bayesian methods offer population forecasters?

, 2010
The Bayesian approach has a number of attractive properties for probabilistic forecasting. In this paper, we apply Bayesian time series models to obtain future population estimates with uncertainty for England and Wales.
Smith, Peter W.F., Raymer, James, Bijak, Jakub, Abel, Guy J., Forster, Jonathan J.   +4 more
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Metastasis on pause: How dormant tumor cells stay hidden within the tumor microenvironment and evade immune surveillance

Molecular Oncology, EarlyView.
Dormant cancer cells can hide in distant organs for years, evading treatment and the immune system. This review highlights how signals from the surrounding tissue and immune environment keep these cells inactive or trigger their reawakening. Understanding these mechanisms may help develop therapies to eliminate or control dormant cells and prevent ...
Kanishka Tiwary, Jose Javier Bravo‐Cordero   +1 more
wiley   +1 more source

Limited penetrance of dominantly inherited AIRE variants in a population-based cohort. [PDF]

Hum Mol Genet
Ramchand SN, Leech JM, Sharp LN, Bonfield G, Luckett AM, Weedon MN, Patel KA, Hawkes G, Johnson MB.   +8 more
europepmc   +1 more source

The Promise of Evidence-Based Policymaking, Final Report and Appendices A-D

, 2017
Final report of the Commission on Evidence-Based Policymaking (CEP) describing their activities and findings regarding evidence access, privacy protections, accountability, and building capacity.
United States. Commission on Evidence-Based Policymaking
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