Metastatic niche shaped by host factors influences disseminated cancer cell fate
Metastasis is shaped not only by cancer cells but also by the environments they encounter. This review explores how factors such as aging, diet, the microbiome, lifestyle, and environmental exposures remodel organ‐specific niches in the lung, liver, bone, and brain, influencing where metastatic cells survive, remain dormant, or grow, and ultimately ...
Gwennan Delyth Ward +2 more
wiley +1 more source
Transient oligomers formed by intrinsically disordered proteins may be ‘invisible’ to direct detection yet remain accessible to solution NMR through equilibrium‐exchange measurements and pressure‐jump experiments. Complementary methods report on mass, stoichiometry, selected distance distributions, morphology, and internal packing.
Martin D. Gelenter, Ad Bax
wiley +1 more source
Bibliography of Finnish Population Research, 1965-1968 [PDF]
Institute, Population Research +1 more
core +1 more source
Population ageing and the labour market: Some insights from Australia
This paper summarises the major dimensions of current and impending ageing in Australia and its impact on the workforce. Australia has a more marked “post war baby boom” effect than most OECD countries with baby boomers making up 42 percent of the ...
Hugo, G.
core
The changing Aboriginal and Torres Strait Islander population: evidence from the 2006–11 Australian Census Longitudinal Dataset [PDF]
Populations change and grow through time. Keeping track of this change and associated improvements or worsening in outcomes is a key role for statistical agencies and researchers, and is necessary for an informed and evidence-based policy debate. This is
Nicholas Biddle +3 more
core
DNA ligase LigE increases bacterial transformation with damaged extracellular DNA
The DNA ligase LigE from the naturally competent Gram‐negative bacterium Neisseria gonorrhoaea increases transformation with cut extracellular DNA. This process is ATP‐dependent and relies on the catalytic activity of LigE; it also requires that LigE contains an intact periplasmic localisation sequence, indicating that ligE functions in the periplasm ...
Jolyn Pan +4 more
wiley +1 more source
Going viral − Virus‐targeting nanobodies for research, diagnostics and therapy
The increasing prevalence of viral diseases represents a major threat for global human health. Nanobodies, small binding fragments derived from camelid heavy‐chain antibodies, offer versatile tools for viral research, diagnostics, and antiviral therapy.
Domenic Ebert, Ulrich Rothbauer
wiley +1 more source
Population trends, convictions and imprisonment: Demographic divergence, dichotomy and diversity [PDF]
The links between population patterns and trends, and policy and planning for the justice system is important. The trends in the number of convictions and imprisonments by regional councils are investigated for the period 1986 to 2001. This does not just
Pool, Ian, Baxendine, Sandra
core
Collaborative research: population-based data and validation are necessary
openaire +3 more sources
How structural disorder and polyelectrolyte properties of prothymosin α enable its large interactome
In this review, complexes of the fully disordered and highly negatively charged prothymosin α are collected, described, and discussed. Linked to its poly‐electrostatic character, prothymosin α engages a large interactome through multiple different binding modes ranging from fully disordered complexes to short linear motif (SLiM)‐driven interactions ...
Ketty C. Tamburrini +3 more
wiley +1 more source

