Results 121 to 130 of about 11,142,294 (286)

Pan Trapping and Malaise Trapping: A Comparison of Bee Collection Techniques in Subalpine Meadows

Diversity
Public lands, managed for multiple uses such as logging, mining, grazing, and recreation, also support vital environmental services like wild bee pollination. A trending decline in wild bees has heightened interest in documenting these key pollinators in
Nicholas Anderson, Steven Petersen, Robert Johnson, Tyson Terry, Jacqueline Kunzelman, David Lariviere, Val Anderson   +6 more
doaj   +1 more source

Engineering peptides into antibodies—opportunities and strategies for therapeutic innovation

FEBS Letters, EarlyView.
Peptides and antibodies occupy complementary therapeutic niches. Peptides recognize difficult targets in a compact format, while antibodies add specificity, long half‐life, and effector functions. This review examines strategies that merge both modalities—peptide grafting into loops, terminal and Fc fusions, and bioconjugation—highlighting how ...
Jinling Wang, Ruslana Romaniuk, Hristo L. Svilenov   +2 more
wiley   +1 more source

Use of Guideline-Recommended Heart Failure Drugs in High-, Middle-, and Low-Income Countries: A Systematic Review and Meta-Analysis

Global Heart
Optimal use of guideline-directed medical therapy (GDMT) can prevent hospitalization and mortality among patients with heart failure (HF). We aimed to assess the prevalence of GDMT use for HF across geographic regions and country-income levels.
Gautam Satheesh, Rupasvi Dhurjati, Laura Alston, Fisaha Tesfay, Rashmi Pant, Ehete Bahiru, Claudia Bambs, Anubha Agarwal, Sanne A. E. Peters, Abdul Salam, Isabelle Johansson   +10 more
doaj   +1 more source

Liver organoids: modelling complexity in homeostasis and disease

FEBS Letters, EarlyView.
Studying liver in vitro has been challenging because simple 2D cell cultures fail to capture liver's cellular and architectural complexity. To bridge this gap, scientists increasingly use organoids, 3D liver models which better mimic liver composition and function. This review examines recent advances in liver organoid complexity and realism, discusses
Anna M. Dowbaj, Meritxell Huch
wiley   +1 more source

AZERBAYCAN NÜFUSUNUN EĞİTİM AÇISINDAN ANALİZİ

Selçuk Üniversitesi Sosyal Bilimler Enstitüsü Dergisi, 2005
Azerbaycan nüfusunun eğitim durumu tarihsel süreç içerisinde çok fazla değişime uğramıştır. Ülke nüfusunun eğitim durumu özellikle Sovyet Döneminden günümüze kadar geçen sürede büyük değişime uğramıştır. Örneğin, 1926 yılında ülke nüfusunun yaklaşık % 30’
Rehman Seferov, Akif Akkuş
doaj  

The microbiome in human skin aging

FEBS Letters, EarlyView.
Age‐related skin changes encompass the well‐known visible phenotypic alterations, together with microbiome dysbiosis and a series of molecular aging hallmarks. These hallmarks characterize not only a fully stablished aged phenotype but also the skin aging process itself.
Manuel Huerta Arana, Cornelia Wiegand, Omid Omrani, Mario Fabri   +3 more
wiley   +1 more source

SALİHLİ’NİN MANİSA NÜFUS ÖZELLİKLERİ

Selçuk Üniversitesi Sosyal Bilimler Enstitüsü Dergisi, 2008
Araştırma sahasınıoluşturan Salihli, Manisa iline bağlıbir ilçe olup Ege Bölgesi’nin Asıl Ege Bölümü’nde yer alır. Saha 28o10ıve 28o40ıdoğu boylamlarıile 38o20ıve 38o45ıkuzey enlemleri arasında konumlanmıştır.
Ayhan Akış, Hasan Ozan Başkan
doaj  

From populism to population healthcare [PDF]

Journal of the Royal Society of Medicine, 2016
openaire   +2 more sources

Partial depletion of plasminogen activator inhibitor‐1 decreases subcutaneous fat cell hypertrophy and liver cholesterol in high‐fat‐fed female mice

FEBS Letters, EarlyView.
Obesity raises blood levels of PAI‐1, a protein linked to metabolic dysfunction‐associated steatotic liver disease in people with obesity. In female mice fed a high‐fat diet, partially lowering PAI‐1 led to smaller subcutaneous fat cells and lower liver cholesterol, without changing body weight or insulin sensitivity.
Claudia E. Ramirez Bustamante, Robert Sharp, Pradip K. Saha, Elizabeth S. Anaya, Elizabeth L. Lieu, Evelyn L. de Groot, Pooja Patel, Mi Jeong Heo, Aaron R. Cox, Kang Ho Kim, Sean M. Hartig   +10 more
wiley   +1 more source

Ligand‐dependent transcriptional heterogeneity in cell cycle gene expression delays G1/S entry

FEBS Letters, EarlyView.
EGF and HRG induce distinct G1/S progression programs in ErbB2‐amplified BT474 breast cancer cells. Despite activating the potent ErbB2–ErbB3 heterodimer, HRG does not accelerate cell‐cycle entry. Instead, EGF promotes earlier restriction‐point passage via ERK–FOS signaling, whereas HRG activates the AKT–MYC axis, driving transcriptional heterogeneity ...
Ririn Rahmala Febri, Ayaka Nagasato‐Ichikawa, Keita Iida, Shuhei Kimura, Akira Imamoto, Mariko Okada   +5 more
wiley   +1 more source