Results 161 to 170 of about 5,816,938 (249)

Genetic variability and associations of Trakehner and other horse populations in Lithuania. [PDF]

Arch Anim Breed
Račkauskaitė A, Šveistienė R, Razmaitė V, Jatkauskienė V, Marašinskienė Š.   +4 more
europepmc   +1 more source

Modelling stem cell differentiation related processes—A practical overview for biologists

FEBS Letters, EarlyView.
Stem cell differentiation is complex and difficult to control experimentally. This review introduces suitable computational modelling approaches that can support stem cell research, from mechanistic ODE and abstract models to multiscale and deep learning methods.
Ricco Zeegelaar, Xinqi Yan, Lucas F. Jansen Klomp, Stefano Schivo, Janine N. Post   +4 more
wiley   +1 more source

Design and analysis strategies for robust microbiome ageing research

FEBS Letters, EarlyView.
The gut microbiome changes with age and associates with age‐related morbidity and mortality, establishing it as a potential biomarker and intervention target for ageing. Realising this potential requires methodological rigour, yet distinguishing biological signals from methodological artefacts remains challenging across cohorts. This review provides an
Mark Olenik, İsmail Güderer, Yi Wang, Tayyaba Alvi, Prasoon Pandey, Handan Melike Dönertaş   +5 more
wiley   +1 more source

Long-Term Cardiometabolic Outcomes in Children With Metabolically Healthy and Unhealthy Obesity.

JAMA Pediatr
Putri RR, Danielsson P, Hagman E, Marcus C.   +3 more
europepmc   +1 more source

Increasing trends in adult obesity in Greenland: a serial cross-sectional study from 1999 through 2018. [PDF]

Int J Circumpolar Health
Nielsen H, Landbo C, Senftleber N, Larsen CVL, Bjerregaard P, Sørensen TIA, Jørgensen ME, Christensen DL, Byberg S.   +8 more
europepmc   +1 more source

Investigating transcription factor dynamics in health and disease using FRAP

FEBS Letters, EarlyView.
FRAP analysis of GFP‐tagged transcription factors reveals how molecular mobility and target engagement change in response to drug treatment. By combining live‐cell imaging, quantitative model fitting, and statistical analysis, this approach uncovers transcription factor dynamics linked to disease mechanisms, providing a powerful framework for ...
Kannan Govindaraj, Carolina Vazquez Garzon, Jose Joaquin Velasco, Janine N. Post   +3 more
wiley   +1 more source

Recent population history in Swedish cattle breeds. [PDF]

Genet Sel Evol
Adepoju D, Ohlsson JI, Klingström T, Rius-Vilarrasa E, Johansson AM, Johnsson M.   +5 more
europepmc   +1 more source

Microbiome‐blood–brain barrier interactions in aging — mechanisms and therapeutic potential

FEBS Letters, EarlyView.
Aging reshapes the gut microbiome (↓SCFA‐producing commensals; ↑pro‐inflammatory outputs), shifting circulating metabolites (↓SCFAs; ↑LPS, ↑TMAO, ↑PAA) that act at the BBB to increase nonspecific transcytosis, alter transport, and promote astrocyte reactivity, heightening brain vulnerability.
Daniel Cuervo‐Zanatta, Hari Baskar Balasubramanian, Amir Pasokh, Marietta Zille   +3 more
wiley   +1 more source

Transcriptomic genotyping elucidates the population structure and demographic history of the endangered poison frog Oophaga vicentei (Anura: Dendrobatidae). [PDF]

BMC Genomics
Cajigas Gandia A, Pröhl H, Oikonomaki VM, Ibáñez R, Rodríguez A.   +4 more
europepmc   +1 more source

Epidemiology and Population Health: By the Population (Community Health Workers) and for the Population

Revista Argentina de Cardiologia, 2016
openaire   +1 more source