Results 11 to 20 of about 13,472,802 (342)

FinnGen provides genetic insights from a well-phenotyped isolated population

open access: yesNature, 2023
Genome-wide association studies of individuals from an isolated population (data from the Finnish biobank study FinnGen) and consequent meta-analyses facilitate the identification of previously unknown coding variant associations for both rare and common
M. Kurki   +167 more
semanticscholar   +1 more source

Impact of COVID-19 pandemic on mental health in the general population: A systematic review

open access: yesJournal of Affective Disorders, 2020
Background As a major virus outbreak in the 21st century, the Coronavirus disease 2019 (COVID-19) pandemic has led to unprecedented hazards to mental health globally.
Jiaqi Xiong   +10 more
semanticscholar   +1 more source

Stellar population synthesis at the resolution of 2003 [PDF]

open access: yes, 2003
We present a new model for computing the spectral evolution of stellar populations at ages between 1 x 10 5 and 2 x 10 1 0 yr at a resolution of 3 A across the whole wavelength range from 3200 to 9500 A for a wide range of metallicities.
G. Bruzual, S. Charlot
semanticscholar   +1 more source

GenAlEx 6.5: genetic analysis in Excel. Population genetic software for teaching and research—an update

open access: yesBioinform., 2012
Summary: GenAlEx: Genetic Analysis in Excel is a cross-platform package for population genetic analyses that runs within Microsoft Excel. GenAlEx offers analysis of diploid codominant, haploid and binary genetic loci and DNA sequences.
R. Peakall, P. Smouse
semanticscholar   +1 more source

A map of human genome variation from population-scale sequencing

open access: yesNature, 2010
The 1000 Genomes Project aims to provide a deep characterization of human genome sequence variation as a foundation for investigating the relationship between genotype and phenotype.
G. Abecasis   +7 more
semanticscholar   +1 more source

Population Structure and Eigenanalysis

open access: yesPLoS Genetics, 2006
Current methods for inferring population structure from genetic data do not provide formal significance tests for population differentiation. We discuss an approach to studying population structure (principal components analysis) that was first applied ...
N. Patterson, A. Price, D. Reich
semanticscholar   +1 more source

Communication and Language Profiles of Children Treated for Posterior Fossa Brain Tumors

open access: yesPediatric Blood &Cancer, EarlyView.
ABSTRACT Background Cognitive and language deficits are frequently reported sequelae of posterior fossa brain tumors (PFBT). Typically, delayed onset impedes prompt assessment and early intervention. This has devastating implications for quality of life.
Zara Sved   +4 more
wiley   +1 more source

The HIT Network for Children and Adolescents With CNS Tumors Facilitates Improvements of Diagnostic Assessments, Multimodal Treatments, Individual Counseling, and Research in Germany, Austria, and Switzerland

open access: yesPediatric Blood &Cancer, EarlyView.
ABSTRACT Background The HIT network was established in 2000 to create a population‐based structure aiming to improve survival rates and reduce late effects for children with central nervous system (CNS) tumors by conducting comprehensive clinical trials.
Stefan Rutkowski   +59 more
wiley   +1 more source

Open-access bacterial population genomics: BIGSdb software, the PubMLST.org website and their applications

open access: yesWellcome Open Research, 2018
The PubMLST.org website hosts a collection of open-access, curated databases that integrate population sequence data with provenance and phenotype information for over 100 different microbial species and genera. Although the PubMLST website was conceived
K. Jolley, J. Bray, M. Maiden
semanticscholar   +1 more source

Stressful Events Reported by Childhood Cancer Survivors and Community Controls From the St. Jude Lifetime (SJLIFE) Cohort: A Mixed Method Study

open access: yesPediatric Blood &Cancer, EarlyView.
ABSTRACT Introduction Characterizing stressful events reported by childhood cancer survivors experienced throughout the lifespan may help improve trauma‐informed care relevant to the survivor experience. Methods Participants included 2552 survivors (54% female; 34 years of age) and 469 community controls (62% female; 33 years of age) from the St.
Megan E. Ware   +13 more
wiley   +1 more source

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