Habitation Altitude and Left Ventricular Diastolic Function: A Population‐Based Study
Background Although numerous studies have been published evaluating the positive or negative effects of altitude on cardiovascular disease, many of them are conflicting.
Congyi Zheng+10 more
doaj +1 more source
Population and Regulation [PDF]
We present a model of efficient regulation along the lines of Demsetz (1967). In this model, setting up and running regulatory institutions takes a fixed cost, and therefore jurisdictions with larger populations affected by a given regulation are more likely to have them. Consistent with the model, we find that higher population U.S.
Casey B. Mulligan+3 more
openaire +4 more sources
Dendritic cells steering antigen and leukocyte traffic in lymph nodes
Dendritic cells are key players in the activation of T cells and their commitment to effector function. In this In a Nutshell Review, we will discuss how dendritic cells guide the trafficking of antigen and leukocytes in the lymph node, thus influencing T‐cell activation processes. Dendritic cells (DCs) play a central role in initiating and shaping the
Enrico Dotta+3 more
wiley +1 more source
A dynamical trichotomy for structured populations experiencing positive density-dependence in stochastic environments [PDF]
Positive density-dependence occurs when individuals experience increased survivorship, growth, or reproduction with increased population densities. Mechanisms leading to these positive relationships include mate limitation, saturating predation risk, and cooperative breeding and foraging. Individuals within these populations may differ in age, size, or
arxiv +1 more source
The dual nature of TDC – bridging dendritic and T cells in immunity
TDC are hematopoietic cells combining dendritic and T cell features. They reach secondary lymphoid organs (SLOs) and peripheral organs (liver and lungs) after FLT3‐dependent development in the bone marrow and maturation in the thymus. TDC are activated and enriched in SLOs upon viral infection, suggesting that they might play unique immune roles, since
Maria Nelli, Mirela Kuka
wiley +1 more source
On the Three Properties of Stationary Populations and knotting with Non-Stationary Populations [PDF]
A population is considered stationary if the growth rate is zero and the age structure is constant. It thus follows that a population is considered non-stationary if either its growth rate is non-zero and/or its age structure is non-constant. We propose three properties that are related to the stationary population identity (SPI) of population biology ...
arxiv +1 more source
In vivo IL‐10 produced by tissue‐resident tolDC is involved in maintaining/inducing tolerance. Depending on the agent used for ex vivo tolDC generation, cells acquire common features but prime T cells towards anergy, FOXP3+ Tregs, or Tr1 cells according to the levels of IL‐10 produced. Ex vivo‐induced tolDC were administered to patients to re‐establish/
Konstantina Morali+3 more
wiley +1 more source
Tailored inference for finite populations: conditional validity and transfer across distributions [PDF]
Parameters of sub-populations can be more relevant than super-population ones. For example, a healthcare provider may be interested in the effect of a treatment plan for a specific subset of their patients; policymakers may be concerned with the impact of a policy in a particular state within a given population.
arxiv
Contemporary changes in the ethnic structure of the population in the Autonomous Province of Kosovo and Metohija [PDF]
Twenty years (1999 - 2019) after the end of the conflict in the Autonomous Province of Kosovo and Metohija, it can be stated that nowhere in Europe is there such ethnic segregation of the population as is the case with the AP of Kosovo and Metohija ...
Milosavljević Saša, Medojević Jovo
doaj
FoxO1 signaling in B cell malignancies and its therapeutic targeting
FoxO1 has context‐specific tumor suppressor or oncogenic character in myeloid and B cell malignancies. This includes tumor‐promoting properties such as stemness maintenance and DNA damage tolerance in acute leukemias, or regulation of cell proliferation and survival, or migration in mature B cell malignancies.
Krystof Hlavac+3 more
wiley +1 more source