Results 41 to 50 of about 6,246,292 (318)
This study reveals how prime editing guide RNA (pegRNA) secondary structure and reverse transcriptase template length affect prime editing efficiency in correcting the phospholamban R14del cardiomyopathy‐associated mutation. Insights support the design of structurally optimized enhanced pegRNAs for precise gene therapy.
Bing Yao+7 more
wiley +1 more source
Single‐cell insights into the role of T cells in B‐cell malignancies
Single‐cell technologies have transformed our understanding of T cell–tumor cell interactions in B‐cell malignancies, revealing new T‐cell subsets, functional states, and immune evasion mechanisms. This Review synthesizes these findings, highlighting the roles of T cells in pathogenesis, progression, and therapy response, and underscoring their ...
Laura Llaó‐Cid
wiley +1 more source
Uploaded by Plazi for TaxoDros. We do not have abstracts.
openaire +4 more sources
Gossip protocols are simple, robust and scalable and have been consistently applied to many (mostly wired) distributed systems. Nevertheless, most validation in this area has been so far empirical and there is a clear lack of a theoretical counterpart to characterize what can and cannot be computed with gossip protocols.
Bertier, Marin+2 more
openaire +3 more sources
Practice Patterns for Acute Ischemic Stroke Workup: A Longitudinal Population‐Based Study
BackgroundWe examined practice patterns of inpatient testing to identify stroke etiologies and treatable risk factors for acute ischemic stroke recurrence.
Matthew C. Loftspring+11 more
doaj +1 more source
Cyclic nucleotide signaling as a drug target in retinitis pigmentosa
Disruptions in cGMP and cAMP signaling can contribute to retinal dysfunction and photoreceptor loss in retinitis pigmentosa. This perspective examines the mechanisms and evaluates emerging evidence on targeting these pathways as a potential therapeutic strategy to slow or prevent retinal degeneration.
Katri Vainionpää+2 more
wiley +1 more source
Contemporary Demographic Characteristics of Municipality of Bela Palanka [PDF]
Favourable geo-traffic position of Bela Palanka and its surroundings has always been attractive for settlement of population. This is witnessed by numerous archaeological sites from prehistoric, Roman and Byzantine periods.
Dušan Živković
doaj
Exposure to common noxious agents (1), including allergens, pollutants, and micro‐nanoplastics, can cause epithelial barrier damage (2) in our body's protective linings. This may trigger an immune response to our microbiome (3). The epithelial barrier theory explains how this process can lead to chronic noncommunicable diseases (4) affecting organs ...
Can Zeyneloglu+17 more
wiley +1 more source
Three‐dimensional (3D) biological systems have become key tools in lymphoma research, offering reliable in vitro and ex vivo platforms to explore pathogenesis and support precision medicine. This review highlights current 3D non‐Hodgkin lymphoma models, detailing their features, advantages, and limitations, and provides a broad perspective on future ...
Carla Faria+3 more
wiley +1 more source
A few years ago, Camus & Lima (2002) wrote an essay to stimulate ecologists to think about how we define and use a fundamental concept in ecology: the population. They concluded, concurring with Berryman (2002), that a population is ‘a group of individuals of the same species that live together in an area of sufficient size to permit normal ...
openaire +6 more sources