Results 51 to 60 of about 22,891,697 (383)

On Gossip and Populations

open access: yes, 2010
Gossip protocols are simple, robust and scalable and have been consistently applied to many (mostly wired) distributed systems. Nevertheless, most validation in this area has been so far empirical and there is a clear lack of a theoretical counterpart to characterize what can and cannot be computed with gossip protocols.
Bertier, Marin   +2 more
openaire   +2 more sources

Hematopoietic (stem) cells—The elixir of life?

open access: yesFEBS Letters, EarlyView.
The aging of HSCs (hematopoietic stem cells) and the blood system leads to the decline of other organs. Rejuvenating aged HSCs improves the function of the blood system, slowing the aging of the heart, kidney, brain, and liver, and the occurrence of age‐related diseases.
Emilie L. Cerezo   +4 more
wiley   +1 more source

The role and implications of mammalian cellular circadian entrainment

open access: yesFEBS Letters, EarlyView.
At their most fundamental level, mammalian circadian rhythms occur inside every individual cell. To tell the correct time, cells must align (or ‘entrain’) their circadian rhythm to the external environment. In this review, we highlight how cells entrain to the major circadian cues of light, feeding and temperature, and the implications this has for our
Priya Crosby
wiley   +1 more source

Challenges in Stellar Population Studies [PDF]

open access: yes, 2009
The stellar populations of galaxies contain a wealth of detailed information. From the youngest, most massive stars, to almost invisible remnants, the history of star formation is encoded in the stars that make up a galaxy.
Arnaboldi   +28 more
core   +1 more source

Effective Population Size of Korean Populations [PDF]

open access: yesGenomics & Informatics, 2014
Recently, new methods have been developed for estimating the current and recent changes in effective population sizes. Based on the methods, the effective population sizes of Korean populations were estimated using data from the Korean Association Resource (KARE) project. The overall changes in the population sizes of the total populations were similar
openaire   +3 more sources

The zinc finger domains of PARP‐1 are selectively and potently inhibited by the Au(I)‐based drugs sodium aurothiomalate and aurothioglucose

open access: yesFEBS Letters, EarlyView.
PARP‐1 is a key enzyme in the DNA damage response, and its inhibition induces cancer cell death via synthetic lethality. Au(I)‐based drugs, such as aurothioglucose and sodium aurothiomalate, block PARP‐1's DNA‐dependent activity by targeting its zinc finger domains.
Uliana Bashtanova, Melinda Jane Duer
wiley   +1 more source

A Notes on the Blue-winged Teal (Spatula discors) and the influence of solar irradiance in a wetland from Boyacá State, Colombia

open access: yesRivista Italiana di Ornitologia - Research in Ornithology
The Blue-winged Teal (Spatula discors) is a migratory species that has been observed in El Salitre wetland near Paipa (5° 46’48.47”N, 73°07’1.49”W), Boyacá State, Colombia.
Fernando Ramírez
doaj   +1 more source

Real‐time assay of ribonucleotide reductase activity with a fluorescent RNA aptamer

open access: yesFEBS Letters, EarlyView.
Ribonucleotide reductases (RNR) synthesize DNA building blocks de novo, making them crucial in DNA replication and drug targeting. FLARE introduces the first single‐tube real‐time coupled RNR assay, which enables isothermal tracking of RNR activity at nanomolar enzyme levels and allows the reconstruction of allosteric regulatory patterns and rapid ...
Jacopo De Capitani   +4 more
wiley   +1 more source

Population resources of an endangered species Salix lapponum L. in Polesie Lubelskie Region (eastern Poland)

open access: yesActa Agrobotanica, 2014
This research, carried out in the years 2011–2013, aimed to evaluate Salix lapponum stands in the peat bogs of Polesie Lubelskie Region as well as to determine the condition of the population and the changes that have taken place since the 1950’s.
Magdalena Pogorzelec   +3 more
doaj   +1 more source

Disordered but rhythmic—the role of intrinsic protein disorder in eukaryotic circadian timing

open access: yesFEBS Letters, EarlyView.
Unstructured domains known as intrinsically disordered regions (IDRs) are present in nearly every part of the eukaryotic core circadian oscillator. IDRs enable many diverse inter‐ and intramolecular interactions that support clock function. IDR conformations are highly tunable by post‐translational modifications and environmental conditions, which ...
Emery T. Usher, Jacqueline F. Pelham
wiley   +1 more source

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