Results 91 to 100 of about 6,192,624 (283)

Potential impact of controlling opium use prevalence on future cancer incidence in IranResearch in context

open access: yesEClinicalMedicine
Summary: Background: The International Agency for Research on Cancer (IARC) recently classified opium consumption as carcinogenic to humans. This study aimed to estimate the potential reduction in incident cancers by 2035 in Iran, which accounts for 42%
Saeed Nemati   +6 more
doaj   +1 more source

Cancers in Australia in 2010 attributable to the consumption of alcohol

open access: yesAustralian and New Zealand Journal of Public Health, 2015
Objective: To estimate the proportion and numbers of cancers occurring in Australia in 2010 that are attributable to alcohol consumption. Methods: We estimated the population attributable fraction (PAF) of cancers causally associated with alcohol ...
Nirmala Pandeya   +5 more
doaj   +1 more source

Population attributable fraction (PAF) among modifiable breast cancer risk factors according to the menopausal status.

open access: yes, 2018
Population attributable fraction (PAF) among modifiable breast cancer risk factors according to the menopausal status.
Kenneth R. Muir (146404)   +3 more
core   +1 more source

Mitochondrial translation and coordinated cytosolic translation in metabolic homeostasis and disease

open access: yesFEBS Letters, EarlyView.
Mitochondrial function depends on coordinated protein production from the nuclear and mitochondrial genomes. This review highlights how cytosolic and mitochondrial translation, mRNA localization, protein import, and respiratory complex assembly are integrated to maintain mitochondrial proteostasis and function.
Boseon Kim   +4 more
wiley   +1 more source

Preventable cancer cases and deaths attributable to deficit of physical activity in Korea from 2015 to 2030 [PDF]

open access: yesEpidemiology and Health
OBJECTIVES This study aimed to determine the population-attributable fractions (PAFs) of cancers using various calculation methods and to estimate the PAFs of cancer incidence and mortality resulting from deficit in physical activity (DPA) from 2015 to ...
Soseul Sung   +27 more
doaj   +1 more source

SAS Macros for Calculation of Population Attributable Fraction in a Cohort Study Design [PDF]

open access: yes
The population attributable fraction (PAF) is a useful measure for quantifying the impact of exposure to certain risk factors on a particular outcome at the population level.
Esa Virtala   +4 more
core  

Tumour–host interactions in Drosophila: mechanisms in the tumour micro‐ and macroenvironment

open access: yesMolecular Oncology, EarlyView.
This review examines how tumour–host crosstalk takes place at multiple levels of biological organisation, from local cell competition and immune crosstalk to organism‐wide metabolic and physiological collapse. Here, we integrate findings from Drosophila melanogaster studies that reveal conserved mechanisms through which tumours hijack host systems to ...
José Teles‐Reis, Tor Erik Rusten
wiley   +1 more source

Spatial and single‐nuclei transcriptomics reveals idiosyncratic and generic patterns in papillary and anaplastic thyroid cancers

open access: yesMolecular Oncology, EarlyView.
Matched spatial transcriptomics and single‐nuclei RNA‐seq were generated for anaplastic and BRAFV600E papillary thyroid cancers revealing generic and tumor‐specific states occurring in cancer cells and in the tumor microenvironment. In this context, cancer dedifferentiation mirrored organoid maturation through ordered thyroid marker gain/loss ...
Adrien Tourneur   +11 more
wiley   +1 more source

Population attributable fraction and number of stunting cases in children aged 2 y in 2011 attributable to risk factor clusters by region.

open access: yes, 2016
Population attributable fraction and number of stunting cases in children aged 2 y in 2011 attributable to risk factor clusters by region.
Goodarz Danaei (251223)   +9 more
core   +1 more source

Profiling neoadjuvant therapy response in rectal cancer using meta‐analysis of publicly available transcriptomic RNA‐seq datasets

open access: yesMolecular Oncology, EarlyView.
This study integrates publicly available transcriptomic datasets to identify molecular signatures associated with response to neoadjuvant chemoradiotherapy in locally advanced rectal cancer. By analyzing a combination of multiple cohorts with bioinformatics approaches, we reveal biological pathways and immune‐related features that may improve ...
Aleksandra Stanojevic   +10 more
wiley   +1 more source

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