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The population attributable fraction and confounding: buyer beware.
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A history of the population attributable fraction and related measures
Annals of Epidemiology, 2015Since Doll published the first PAF in 1951, it has been a mainstay. Confusion in terminology abounds with regard to these measures. The ability to estimate all of them in case-control studies as well as in cohort studies is not widely appreciated.This article reviews and comments on the historical development of the population attributable fraction ...
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The Population Attributable Fraction as a Measure of the Impact of Warfarin Pharmacogenetic Testing
Pharmacogenomics, 2012We aimed to estimate the population impact of warfarin pharmacogenetic testing (WPGT) across multiple populations.We used the expanded International Warfarin Pharmacogenetics Consortium data set and genotype frequencies from HapMap to simulate dose distributions for each CYP2C9/VKORC1 genotype combination in the different races, and calculated the ...
Ks Chia, Chen Suo, Sze Ling Chan
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Population attributable fraction of smoking to low birth weight in Japan
Pediatrics International, 2004Abstract Background : The purpose of this study is to quantify the population attributable fraction of active and passive smoking for low birth weight in Japan. Methods : A population‐based case‐control study was conducted by mailing self‐report questionnaires. The cases were all singleton low birth weight
Toshiyuki, Ojima +5 more
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Cumulative Risk and Population Attributable Fraction in Prevention
Journal of Clinical Child & Adolescent Psychology, 2003Compares the use of relative risk versus population attributable fraction in determining the target population for multirisk prevention programs in psychology. Results show that relative risk generally increases as a function of cumulative risk. Guided by this measure, prevention programs should target populations with the largest cumulative risk ...
Caroline H, Davis +3 more
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Revisiting the Population Attributable Fraction
EpidemiologyBackground: The population attributable fraction corresponds to the reduction of the outcome had individuals (counter-to-fact) not experienced the exposure scaled by the observed incidence. Estimators proposed by Levin and Miettinen implicitly assume the study population is a random sample of the target population, which is not
Mark Klose +2 more
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Decomposition of the population attributable fraction for two exposures
Annals of Epidemiology, 2018The population attributable fraction (AF) is frequently used to quantify disease burden attributable to exposures. AF is interpreted as the fractional reduction of disease events that would occur if exposures were eliminated. This article aims to provide a decomposition of the overall AF for two exposures into AFs for each of two exposures and AF for ...
Masataka, Taguri, Aya, Kuchiba
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Population-attributable fraction for occupation and asthma
2010Here we review the use of the concept of population-attributable risk (PAR) of asthma associated with occupation and give the context for its interpretation. For asthma there is major interest in delineating the “burden of disease”, because such assessments can inform health care priorities, intervention policies, and assessment of impact once such ...
Kjell Torén, Paul D. Blanc
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[Population attributable fraction: a guideline for disease prevention].
Nederlands tijdschrift voor geneeskunde, 2022The improvement of public health relies on effective strategies for disease prevention, but the optimal preventive strategy is often difficult to determine. The population attributable fraction is a tool that allows policy makers to prioritise among different interventions by quantifying the share of disease in the population that is due to one ...
Amber, Yaqub +2 more
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[Making nomogram to estimate the population attributable fraction].
Zhonghua liu xing bing xue za zhi = Zhonghua liuxingbingxue zazhi, 2010Population attributable fraction (PAF) is an important public health parameter that is familiar to epidemiologists. The calculation of PAF is frequently based on the relative risk (RR) of a risk factor for a certain disease and the prevalence of exposure to the risk factor in the total population (Pe). We introduce here the method for making a nomogram
Hong, Qiu, Ignatius Tak-Sun, Yu
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