Results 141 to 150 of about 11,560,181 (351)
Single‐molecule DNA flow‐stretch assays for high‐throughput DNA–protein interaction studies
FEBS Open Bio, EarlyView.We describe an optimised single‐molecule DNA flow‐stretch assay that visualises DNA–protein interactions in real time. Linear DNA fragments are tethered to a surface and stretched by buffer flow for fluorescence imaging. Using λ and φX174 DNA, this protocol enhances reproducibility and accessibility, providing a versatile approach for studying diverse ...
Ayush Kumar Ganguli +8 more
wiley +1 more source
Improvement of a 1D Population Balance Model for Twin-Screw Wet Granulation by Using Identifiability Analysis. [PDF]
Pharmaceutics, 2021 Barrera Jiménez AA +4 more
europepmc +1 more source
Genetic variation in plasma transferrins of tambaqui, Colossoma macropomum (CUVIER 1818)
, 1985 Blood specimens of tambaqui, Colossoma macropomum, an Amazonian fish of commercial importance, were examined for transferrin variants by treating blood plasma specimens with rivanol before electrophoretic analyses in starch gel media.
Jamieso, A., Teixeira, A.
core
Digital twins to accelerate target identification and drug development for immune‐mediated disorders
FEBS Open Bio, EarlyView.Digital twins integrate patient‐derived molecular and clinical data into personalised computational models that simulate disease mechanisms. They enable rapid identification and validation of therapeutic targets, prediction of drug responses, and prioritisation of candidate interventions.
Anna Niarakis, Philippe Moingeon
wiley +1 more source
Balance Disorders and Their Related Factors Among the Elderly in the Northern Rural Areas of Iran
Caspian Journal of Neurological Sciences, 2019 Background: Aging is a natural and physiological process. Moreover, balance disorders frequently occur in the elderly and cause many morbidities in this population.
Shadman Nemati +7 more
doaj
FEBS Open Bio, EarlyView.Activation of the mitochondrial protein OXR1 increases pSyn129 αSynuclein aggregation by lowering ATP levels and altering mitochondrial membrane potential, particularly in response to MSA‐derived fibrils. In contrast, ablation of the ER protein EMC4 enhances autophagic flux and lysosomal clearance, broadly reducing α‐synuclein aggregates.
Sandesh Neupane +11 more
wiley +1 more source
Optimal control of multidimensional population balance systems for crystal shape manipulation [PDF]
, 2011 Bajcinca, N., Hofmann, S., Menarin, H.
core +2 more sources
FEBS Open Bio, EarlyView.Chemotherapy side effects significantly impact cancer survivors' quality of life. Using protein levels in blood samples from breast cancer patients before and after 12 weeks of taxane treatment, we detected treatment‐dependent changes in calcium signaling and aging pathways associated with cancer recurrence.
Saira Munshani +6 more
wiley +1 more source
The labour force has grown strongly since the mid 2000s due to both a rising participation rate and faster population growth. The increase in participation has been greatest for females and older persons, driven by a range of social and economic factors.
Ellis Connolly +2 more
core
Cutaneous Melanoma Drives Metabolic Changes in the Aged Bone Marrow Immune Microenvironment
Aging and Cancer, EarlyView.Melanoma, the deadliest form of skin cancer, increasingly affects older adults. Our study reveals that melanoma induces changes in iron and lipid levels in the bone marrow, impacting immune cell populations and increasing susceptibility to ferroptosis.
Alexis E. Carey +12 more
wiley +1 more source