Results 171 to 180 of about 23,346,378 (357)

PARP inhibitors elicit distinct transcriptional programs in homologous recombination competent castration‐resistant prostate cancer

open access: yesMolecular Oncology, EarlyView.
PARP inhibitors are used to treat a small subset of prostate cancer patients. These studies reveal that PARP1 activity and expression are different between European American and African American prostate cancer tissue samples. Additionally, different PARP inhibitors cause unique and overlapping transcriptional changes, notably, p53 pathway upregulation.
Moriah L. Cunningham   +21 more
wiley   +1 more source

Economic Burden of Uncontrolled COPD Under Triple Therapy: A Population-Based Study

open access: yesInternational Journal of COPD
Nicolas Molinari,1 Nicolas Roche,2 Anne-Lise Vataire,3 Stanislas Perrier,3 Nicolas Pagès,4 Arnaud Panes,4 Aurélie Schmidt,4 Arnaud Bourdin,5,6 Laurence Watier7 1IDESP, INSERM, PreMEdical INRIA, Univ Montpellier, CHU Montpellier, Montpellier, France ...
Molinari N   +8 more
doaj  

A population-based study of the stratum corneum moisture

open access: yesClinical, Cosmetic and Investigational Dermatology, 2016
Thiago de Farias Pires,1 Ana Paula Azambuja,2 Andrea Roseli Vançan Russo Horimoto,1 Mary Sanae Nakamura,2 Rafael de Oliveira Alvim,1 José Eduardo Krieger,1 Alexandre Costa Pereira1 1Laboratory of Genetics and Molecular Cardiology, Heart ...
Pires TF   +6 more
doaj  

Prevalence of SARS-CoV-2 in Spain (ENE-COVID): a nationwide, population-based seroepidemiological study

open access: yesThe Lancet, 2020
M. Pollán   +109 more
semanticscholar   +1 more source

An Empirical Study of the Effectiveness of 'Forcing Diversity' Based on a Large Population of Diverse Programs [PDF]

open access: yes, 2012
Use of diverse software components is a viable defence against common-mode failures in redundant softwarebased systems. Various forms of "Diversity-Seeking Decisions" (“DSDs”) can be applied to the process of developing, or procuring, redundant ...
Popov, P. T.   +2 more
core  

Characterizing the salivary RNA landscape to identify potential diagnostic, prognostic, and follow‐up biomarkers for breast cancer

open access: yesMolecular Oncology, EarlyView.
This study explores salivary RNA for breast cancer (BC) diagnosis, prognosis, and follow‐up. High‐throughput RNA sequencing identified distinct salivary RNA signatures, including novel transcripts, that differentiate BC from healthy controls, characterize histological and molecular subtypes, and indicate lymph node involvement.
Nicholas Rajan   +9 more
wiley   +1 more source

Excess Mortality in Individuals with Autism Spectrum Disorder: A Population-Based Cohort Study

open access: yesNeuropsychiatric Disease and Treatment
Yu-Hsin Huang,1,2,* Shu-I Wu,1,2 Min-Jing Lee,3– 5,* Yi-Lung Chen,6,7,* Yao-Hsu Yang,8,9 Ting-Yu Kuo,8 Tai-Hsin Hung,3,4 Michael E Dewey,10 Robert Stewart,11,12 Vincent Chin-Hung Chen3,4 1Department of Medicine, MacKay Medical College, New ...
Huang YH   +9 more
doaj  

Trends in the incidence of deep vein thrombosis and pulmonary embolism: a 25-year population-based study.

open access: yesArchives of Internal Medicine, 1998
M. Silverstein   +5 more
semanticscholar   +1 more source

Bridging the gap: Multi‐stakeholder perspectives of molecular diagnostics in oncology

open access: yesMolecular Oncology, EarlyView.
Although molecular diagnostics is transforming cancer care, implementing novel technologies remains challenging. This study identifies unmet needs and technology requirements through a two‐step stakeholder involvement. Liquid biopsies for monitoring applications and predictive biomarker testing emerge as key unmet needs. Technology requirements vary by
Jorine Arnouts   +8 more
wiley   +1 more source

A nomogram for endoscopic screening in a high esophageal squamous cell cancer risk area: results from a population-based study

open access: yesCancer Management and Research, 2019
Jie Xing,1 Li Min,1 Hao Zhang,2 Peng Li,1 Wei Li,1 Fujin Lv,1 Yongjun Wang,1 Zheng Zhang,1 Hengcun Li,1 Qingdong Guo,1 Siyi Wang,1 Yu Zhao,1 Junmin Wang,3 Xiaoyan Shi,4 Anxin Wang,5 Shengtao Zhu,1 Ming Ji,1 Yongdong Wu,1 Shutian Zhang1 On behalf of the ...
Xing J   +18 more
doaj  

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