Results 261 to 270 of about 23,346,378 (357)

Targeted modulation of IGFL2‐AS1 reveals its translational potential in cervical adenocarcinoma

Molecular Oncology, EarlyView.
Cervical adenocarcinoma patients face worse outcomes than squamous cell carcinoma counterparts despite similar treatment. The identification of IGFL2‐AS1's differential expression provides a molecular basis for distinguishing these histotypes, paving the way for personalized therapies and improved survival in vulnerable populations globally.
Ricardo Cesar Cintra, Lucca Paolo Hsu Helmich, Daniel Rodrigues de Bastos, Laura Sichero, Patrícia Savio de Araujo‐Souza, Fabio Passetti, Luisa Lina Villa   +6 more
wiley   +1 more source

Analysis of prognostic factors for advanced pancreatic neuroendocrine carcinoma: A population-based study. [PDF]

Medicine (Baltimore)
Zhang J, Zhang S, Xu Y, Wang X, Cheng J, Leng X.   +5 more
europepmc   +1 more source

RIPK4 function interferes with melanoma cell adhesion and metastasis

Molecular Oncology, EarlyView.
RIPK4 promotes melanoma growth and spread. RIPK4 levels increase as skin lesions progress to melanoma. CRISPR/Cas9‐mediated deletion of RIPK4 causes melanoma cells to form less compact spheroids, reduces their migratory and invasive abilities and limits tumour growth and dissemination in mouse models.
Norbert Wronski, Sławomir Lasota, Ewelina Madej, Anna A. Brożyna, Małgorzata Szczygieł, Agnieszka Harazin‐Lechowska, Jan Czerbniak, Janusz Rys, Jaroslaw Czyz, Agnieszka Wolnicka‐Glubisz   +9 more
wiley   +1 more source

Correction: Survival disparities and predictors in gastric cancer: a population-based study from Kazakhstan (2012-2023). [PDF]

Front Oncol
Rakhmankulova A, Sakko Y, Kerimkulov A, Mamlin M, Shalekenov S, Zharlyganova D, Manatova A, Kuanysh Z, Burkitbayev Z, Gaipov A.   +9 more
europepmc   +1 more source

Engineered extracellular vesicles enriched with the miR‐214/199a cluster enhance the efficacy of chemotherapy in ovarian cancer

Molecular Oncology, EarlyView.
Loss of the miR‐214/199a cluster is associated with recurrence in ovarian cancer. Engineered small extracellular vesicles (m214‐sEVs) elevate miR‐214‐3p/miR‐199a‐5p in tumor cells, suppress β‐catenin, TLR4, and YKT6 signaling, reprogram tumor‐derived sEV cargo, reduce chemoresistance and migration, and enhance carboplatin efficacy and survival in ...
Weida Wang, Ayesha Alvero, Yi Qin, Mingjin Wang, Alexandra Fox, Yanfeng Li, Michael Millman, Amy Kemper, Gil Mor, Xian Shuang Liu, Michael Chopp, Zheng Gang Zhang, Yi Zhang   +12 more
wiley   +1 more source

Pericardial Mesothelioma: Diagnostic and Therapeutic Management, a Population-Based Study in Italy. [PDF]

Cancers (Basel)
Stella S, Consonni D, Ceresoli GL, Dallari B, Perduri R, Storchi C, Migliore E, Gangemi M, Genova C, Benfatto L, Comiati V, Zabeo V, Piro S, Giovannetti L, Grappasonni I, Pascucci C, Larese Filon F, D'Agostin F, Vimercati L, Cozzi I, Calista F, Cascone G, Angelillo IF, Binazzi A, Marinaccio A, Mensi C.   +25 more
europepmc   +1 more source

Overview of molecular signatures of senescence and associated resources: pros and cons

FEBS Open Bio, EarlyView.
Cells can enter a stress response state termed cellular senescence that is involved in various diseases and aging. Detecting these cells is challenging due to the lack of universal biomarkers. This review presents the current state of senescence identification, from biomarkers to molecular signatures, compares tools and approaches, and highlights ...
Orestis A. Ntintas, Sylvia Vagena, Pavlos Pantelis, Giorgos Theocharous, Russel Petty, Konstantinos Evangelou, Vassilis G. Gorgoulis   +6 more
wiley   +1 more source

Association Between Statin Use and Glaucoma Risk: A Population-Based Study. [PDF]

Invest Ophthalmol Vis Sci
Pan SY, Weng CH, Tien PT, Lu YA, Huang YH, Lin HJ, Cheng YD, Hsieh YW, Ho WT, Huang SP, Cho DY, Lin HJ, Wang IJ, Chou CC.   +13 more
europepmc   +1 more source

Day/night variations of myeloid and lymphoid cell subsets in the murine inguinal lymph node

FEBS Open Bio, EarlyView.
The circadian system is involved in the temporal regulation of the immune system. Our study reveals that two innate immune populations, NKT cells and neutrophils, predominate at the beginning of the day in healthy mice, highlighting how the time of day influences immune responses.
Paula M. Wagner, César G. Prucca, Lucia Boffelli, Virginia A. Piqueras, Silvia G. Correa, Mariana Maccioni, Mario E. Guido   +6 more
wiley   +1 more source