Results 141 to 150 of about 6,857,695 (306)
Molecular Oncology, EarlyView.Tumors contain diverse cellular states whose behavior is shaped by context‐dependent gene coordination. By comparing gene–gene relationships across biological contexts, we identify adaptive transcriptional modules that reorganize into distinct vulnerability axes.
Brian Nelson +9 more
wiley +1 more source
Molecular Oncology, EarlyView.Glioma cells mainly express the endothelin receptor EDNRB, while EDNRA is restricted to a perivascular tumor subpopulation. Endothelin signaling reduces glioma cell proliferation while promoting migration and a proneural‐to‐mesenchymal transition associated with poor prognosis. This pathway activates Ca2+, K+, ERK, and STAT3 signalings and is regulated
Donovan Pineau +36 more
wiley +1 more source
[Characteristics of the Gypsy population].
Statisztikai szemle : a Magyar Kozponti Statisztikai Hivatal folyoirata, 1997 "The study sums up the number and socio-economic characteristics of [the] gipsy population in Hungary. The history of gipsy surveys, dating back more than one hundred years, is reviewed.... The present situation is described drawing on the 1990 population census and the data of a special gipsy survey carried out in 1993. In the course of their analysis
A, Meszaros, J, Foti
openaire +1 more source
From SHIW to IT-SILC: Construction and Representativeness of the New CAPP_DYN First-Year Population [PDF]
This paper describes the construction of the initial population in CAPP_DYN and illustrates the degree of representativeness of the Italian population in 2006.
Donatella fresu, Emanuele Ciani
core
Molecular Oncology, EarlyView.Loss of the miR‐214/199a cluster is associated with recurrence in ovarian cancer. Engineered small extracellular vesicles (m214‐sEVs) elevate miR‐214‐3p/miR‐199a‐5p in tumor cells, suppress β‐catenin, TLR4, and YKT6 signaling, reprogram tumor‐derived sEV cargo, reduce chemoresistance and migration, and enhance carboplatin efficacy and survival in ...
Weida Wang +12 more
wiley +1 more source
Interrogating the immune landscape of microsatellite stable RAS‐mutated colon cancer
Molecular Oncology, EarlyView.COLOSSUS project RAS‐mutated MSS colon cancer study explored transcriptomics and immune cell density by immunohistochemistry (IHC), Immunoscore (IS), ISIC/TuLIS scores, mutation counts, and detected different prevalences but similar microenvironment composition across immune markers with clinical relevance for future immunotherapy combination ...
Rodrigo Dienstmann +61 more
wiley +1 more source
Characteristics of populism in France
Govor/SpeechOvim radom nastoji se analizirati obilježja populizma u Francuskoj. Nastoji se dati uvid u pojam, obilježja i vrste populizma, kao i okolnosti koje pogoduju njegovom nastajanju i jačanju posljednja dva desetljeća. Radom se nastoje analizirati sadržajna i stilska obilježja populizma. Radom se, koristeći metodu analize sadržaja, također nastoji dati uvid
openaire +1 more source
Molecular Oncology, EarlyView.Cytarabine is a key therapy for acute myeloid leukaemia (AML), but its efficacy is limited by the dNTPase SAMHD1, which hydrolyses its active metabolite. Screening nucleotide biosynthesis inhibitors revealed that IMPDH inhibitors selectively sensitise SAMHD1‐proficient AML cells to cytarabine.
Miriam Yagüe‐Capilla +9 more
wiley +1 more source
Infantile Haemangioma in the Romanian Paediatric Population-Characteristics and Therapeutic Approaches. [PDF]
Children (Basel), 2023 Raicu AM +4 more
europepmc +1 more source
Somatic mutational landscape in von Hippel–Lindau familial hemangioblastoma
Molecular Oncology, EarlyView.The causes of central nervous system (CNS) hemangioblastoma in Von Hippel–Lindau (vHL) disease are unclear. We used Whole Exome Sequencing (WES) on familial hemangioblastoma to investigate events that underlie tumor development. Our findings suggest that VHL loss creates a permissive environment for tumor formation, while additional alterations ...
Maja Dembic +5 more
wiley +1 more source